iris Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The circular pigmented membrane behind the cornea, perforated by the pupil; the most anterior portion of the vascular tunic of the eye, it is made up of a flat bar of circular muscular fibers surrounding the pupil, a thin layer of smooth muscle fibers by which the pupil is dilated, thus regulating the amount of light entering the eye, and posteriorly two layers of pigmented epithelial cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000653)
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Genes

21 genes co-occuring with the biological term iris in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APOE apolipoprotein E
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1QTNF5 C1q and tumor necrosis factor related protein 5
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FLT1 fms-related tyrosine kinase 1
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HPS4 Hermansky-Pudlak syndrome 4
IL6 interleukin 6
LOXL1 lysyl oxidase-like 1
OCA2 oculocutaneous albinism II
PAX6 paired box 6
PLEKHA7 pleckstrin homology domain containing, family A member 7
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TNF tumor necrosis factor
TP53 tumor protein p53