irradiation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

222 genes co-occuring with the biological term irradiation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACTA2 actin, alpha 2, smooth muscle, aorta
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMBP alpha-1-microglobulin/bikunin precursor
ANXA2 annexin A2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
ARRB1 arrestin, beta 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BORA bora, aurora kinase A activator
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CALR calreticulin
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CDC25A cell division cycle 25A
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CEP164 centrosomal protein 164kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COMT catechol-O-methyltransferase
COPS5 COP9 signalosome subunit 5
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUEDC2 CUE domain containing 2
CUL4A cullin 4A
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DCK deoxycytidine kinase
DCLRE1C DNA cross-link repair 1C
DCN decorin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DEFB4A defensin, beta 4A
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DROSHA drosha, ribonuclease type III
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EGFR epidermal growth factor receptor
EI24 etoposide induced 2.4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
FAM168A family with sequence similarity 168, member A
FAS Fas cell surface death receptor
FBXO18 F-box protein, helicase, 18
FBXO5 F-box protein 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLCN folliculin
FMOD fibromodulin
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
GCLM glutamate-cysteine ligase, modifier subunit
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HAL histidine ammonia-lyase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIRA histone cell cycle regulator
HIST2H2AC histone cluster 2, H2ac
HK2 hexokinase 2
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOXB9 homeobox B9
HSF1 heat shock transcription factor 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL33 interleukin 33
IL6 interleukin 6
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGAV integrin, alpha V
JUN jun proto-oncogene
KDR kinase insert domain receptor
KIN Kin17 DNA and RNA binding protein
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LGALS7 lectin, galactoside-binding, soluble, 7
LOC401131 uncharacterized LOC401131
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGMT O-6-methylguanine-DNA methyltransferase
MIR125B1 microRNA 125b-1
MIR155 microRNA 155
MIR15B microRNA 15b
MIR193A microRNA 193a
MIR203A microRNA 203a
MIR340 microRNA 340
MIR34A microRNA 34a
MIR449A microRNA 449a
MIR525 microRNA 525
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MRC2 mannose receptor, C type 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PFN1 profilin 1
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIAS1 protein inhibitor of activated STAT, 1
PIDD1 p53-induced death domain protein 1
PLAUR plasminogen activator, urokinase receptor
PLK3 polo-like kinase 3
POLH polymerase (DNA directed), eta
POLQ polymerase (DNA directed), theta
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRK protein tyrosine phosphatase, receptor type, K
PTTG1 pituitary tumor-transforming 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REC8 REC8 meiotic recombination protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REG4 regenerating islet-derived family, member 4
RHOA ras homolog family member A
RNF113A ring finger protein 113A
RPAIN RPA interacting protein
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RXRA retinoid X receptor, alpha
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT3 sirtuin 3
SMAD7 SMAD family member 7
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAI1 snail family zinc finger 1
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK5 serine peptidase inhibitor, Kazal type 5
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TK1 thymidine kinase 1, soluble
TLR2 toll-like receptor 2
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP2 TNFAIP3 interacting protein 2
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TPX2 TPX2, microtubule-associated
TRIM13 tripartite motif containing 13
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTK TTK protein kinase
TXN thioredoxin
UIMC1 ubiquitin interaction motif containing 1
USP28 ubiquitin specific peptidase 28
UVRAG UV radiation resistance associated
VEGFA vascular endothelial growth factor A
WRNIP1 Werner helicase interacting protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6