irritable bowel syndrome Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A syndrome that is a functional bowel disorder characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause. (Human Disease Ontology, DOID_9778)
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Genes

23 genes associated with the disease irritable bowel syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
CCK cholecystokinin
FGFR4 fibroblast growth factor receptor 4
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
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