irs-1 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description insulin receptor substrate 1|This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 3667)
Similar Terms
Downloads & Tools

Genes

47 proteins co-occuring with the biological term irs-1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARRB1 arrestin, beta 1
BLVRA biliverdin reductase A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELK1 ELK1, member of ETS oncogene family
FBXW8 F-box and WD repeat domain containing 8
FOXO1 forkhead box O1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
IGF1R insulin-like growth factor 1 receptor
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
JUN jun proto-oncogene
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NOS3 nitric oxide synthase 3 (endothelial cell)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PGR progesterone receptor
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPARG peroxisome proliferator-activated receptor gamma
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RET ret proto-oncogene
RICTOR RPTOR independent companion of MTOR, complex 2
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TSC2 tuberous sclerosis 2