| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the isocarboxazid-2562 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADRB1 | adrenoceptor beta 1 |
| AGER | advanced glycosylation end product-specific receptor |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARG1 | arginase 1 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATXN3L | ataxin 3-like |
| BTC | betacellulin |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CCDC92 | coiled-coil domain containing 92 |
| CD59 | CD59 molecule, complement regulatory protein |
| CD6 | CD6 molecule |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CSN2 | casein beta |
| CSNK1E | casein kinase 1, epsilon |
| CXORF56 | chromosome X open reading frame 56 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DICER1 | dicer 1, ribonuclease type III |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EFNA3 | ephrin-A3 |
| EFNA5 | ephrin-A5 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ESR1 | estrogen receptor 1 |
| FHL1 | four and a half LIM domains 1 |
| FN1 | fibronectin 1 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLP1R | glucagon-like peptide 1 receptor |
| GSPT2 | G1 to S phase transition 2 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDC | histidine decarboxylase |
| HRH3 | histamine receptor H3 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFNA1 | interferon, alpha 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INHBA | inhibin, beta A |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL3 | kelch-like family member 3 |
| KSR1 | kinase suppressor of ras 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED14 | mediator complex subunit 14 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MRC2 | mannose receptor, C type 2 |
| MTSS1 | metastasis suppressor 1 |
| MYOZ1 | myozenin 1 |
| NCOR2 | nuclear receptor corepressor 2 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NRG1 | neuregulin 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAX2 | paired box 2 |
| PDE7B | phosphodiesterase 7B |
| PDGFRL | platelet-derived growth factor receptor-like |
| PKP1 | plakophilin 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRM2 | protamine 2 |
| PRSS21 | protease, serine, 21 (testisin) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYGB | phosphorylase, glycogen; brain |
| RAB27B | RAB27B, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RAG2 | recombination activating gene 2 |
| RFPL1 | ret finger protein-like 1 |
| RTN2 | reticulon 2 |
| RXRB | retinoid X receptor, beta |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLAMF7 | SLAM family member 7 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TBC1D16 | TBC1 domain family, member 16 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM257 | transmembrane protein 257 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM58 | tripartite motif containing 58 |
| TRIM62 | tripartite motif containing 62 |
| VEGFC | vascular endothelial growth factor C |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALPK1 | alpha-kinase 1 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEP295 | centrosomal protein 295kDa |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CPNE7 | copine VII |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRYGC | crystallin, gamma C |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM120C | family with sequence similarity 120C |
| FAM127A | family with sequence similarity 127, member A |
| FAM131A | family with sequence similarity 131, member A |
| FAM222B | family with sequence similarity 222, member B |
| FAM50B | family with sequence similarity 50, member B |
| FMO4 | flavin containing monooxygenase 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR68 | G protein-coupled receptor 68 |
| GSDMD | gasdermin D |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HSPA2 | heat shock 70kDa protein 2 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KDM7A | lysine (K)-specific demethylase 7A |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0319L | KIAA0319-like |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC6 | leucine rich repeat containing 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICALL2 | MICAL-like 2 |
| MRAS | muscle RAS oncogene homolog |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYH15 | myosin, heavy chain 15 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NOL10 | nucleolar protein 10 |
| NOL12 | nucleolar protein 12 |
| NOP2 | NOP2 nucleolar protein |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDH12 | protocadherin 12 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAT | plasminogen activator, tissue |
| PORCN | porcupine homolog (Drosophila) |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR7 | proline rich 7 (synaptic) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RETN | resistin |
| RFWD3 | ring finger and WD repeat domain 3 |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SH2D4A | SH2 domain containing 4A |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC2A4RG | SLC2A4 regulator |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPAG1 | sperm associated antigen 1 |
| STX11 | syntaxin 11 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TLR1 | toll-like receptor 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM104 | transmembrane protein 104 |
| TMEM115 | transmembrane protein 115 |
| TSPAN13 | tetraspanin 13 |
| UBQLN4 | ubiquilin 4 |
| UCN | urocortin |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF280A | zinc finger protein 280A |
| ZNF76 | zinc finger protein 76 |
| ZNF816 | zinc finger protein 816 |