| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the isocarboxazid-3424 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASPH | aspartate beta-hydroxylase |
| ATF6B | activating transcription factor 6 beta |
| ATP9A | ATPase, class II, type 9A |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCDC28B | coiled-coil domain containing 28B |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CFI | complement factor I |
| COMT | catechol-O-methyltransferase |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ETV5 | ets variant 5 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FAM198B | family with sequence similarity 198, member B |
| FGFR4 | fibroblast growth factor receptor 4 |
| FGL1 | fibrinogen-like 1 |
| FH | fumarate hydratase |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXN2 | forkhead box N2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAL | galanin/GMAP prepropeptide |
| GHRHR | growth hormone releasing hormone receptor |
| GLRA1 | glycine receptor, alpha 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HAP1 | huntingtin-associated protein 1 |
| HBS1L | HBS1-like translational GTPase |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPB11 | heat shock protein family B (small), member 11 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KITLG | KIT ligand |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC647070 | uncharacterized LOC647070 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MCC | mutated in colorectal cancers |
| MED25 | mediator complex subunit 25 |
| MMP3 | matrix metallopeptidase 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MXD3 | MAX dimerization protein 3 |
| NPR2 | natriuretic peptide receptor 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARVA | parvin, alpha |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLAU | plasminogen activator, urokinase |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRAMEF11 | PRAME family member 11 |
| PRR5 | proline rich 5 (renal) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB28 | RAB28, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASAL2 | RAS protein activator like 2 |
| RECQL5 | RecQ protein-like 5 |
| RNF39 | ring finger protein 39 |
| RPL10 | ribosomal protein L10 |
| SBF1 | SET binding factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| STK4 | serine/threonine kinase 4 |
| STRN | striatin, calmodulin binding protein |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D22A | TBC1 domain family, member 22A |
| TCF3 | transcription factor 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMOD1 | tropomodulin 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YY1 | YY1 transcription factor |
| ZNF10 | zinc finger protein 10 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| BAG4 | BCL2-associated athanogene 4 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL9 | B-cell CLL/lymphoma 9 |
| CAPRIN2 | caprin family member 2 |
| CCDC9 | coiled-coil domain containing 9 |
| CENPJ | centromere protein J |
| CEP97 | centrosomal protein 97kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CINP | cyclin-dependent kinase 2 interacting protein |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAAH | fatty acid amide hydrolase |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FANCE | Fanconi anemia, complementation group E |
| FGF23 | fibroblast growth factor 23 |
| FOSL1 | FOS-like antigen 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GOLGA8B | golgin A8 family, member B |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| H2AFY2 | H2A histone family, member Y2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIRA | histone cell cycle regulator |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| IPO8 | importin 8 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| LIG1 | ligase I, DNA, ATP-dependent |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINS | lines homolog (Drosophila) |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYO1D | myosin ID |
| MYO1F | myosin IF |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NUPL2 | nucleoporin like 2 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PODXL2 | podocalyxin-like 2 |
| POU2F1 | POU class 2 homeobox 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRPH | peripherin |
| PTK6 | protein tyrosine kinase 6 |
| RAD51AP1 | RAD51 associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SALL2 | spalt-like transcription factor 2 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH2B3 | SH2B adaptor protein 3 |
| SIK1 | salt-inducible kinase 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SREK1IP1 | SREK1-interacting protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNS2 | tensin 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN14 | tetraspanin 14 |
| VEGFC | vascular endothelial growth factor C |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| WDR76 | WD repeat domain 76 |
| XK | X-linked Kx blood group |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| YIPF3 | Yip1 domain family, member 3 |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |
| ZNF552 | zinc finger protein 552 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
| ZNF652 | zinc finger protein 652 |
| ZW10 | zw10 kinetochore protein |