isoconazole-1372 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the isoconazole-1372 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALAS1 5'-aminolevulinate synthase 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ANKRD12 ankyrin repeat domain 12
ARFRP1 ADP-ribosylation factor related protein 1
ATG12 autophagy related 12
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL7C B-cell CLL/lymphoma 7C
BEX1 brain expressed, X-linked 1
C12ORF29 chromosome 12 open reading frame 29
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCDC94 coiled-coil domain containing 94
CD44 CD44 molecule (Indian blood group)
CHPF2 chondroitin polymerizing factor 2
CPNE3 copine III
CPOX coproporphyrinogen oxidase
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNASE1L1 deoxyribonuclease I-like 1
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DSCR3 Down syndrome critical region 3
DUS2 dihydrouridine synthase 2
DUSP12 dual specificity phosphatase 12
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EIF5 eukaryotic translation initiation factor 5
ELMO2 engulfment and cell motility 2
ENG endoglin
FAM89B family with sequence similarity 89, member B
FANCF Fanconi anemia, complementation group F
FRY furry homolog (Drosophila)
GABPB1 GA binding protein transcription factor, beta subunit 1
GCAT glycine C-acetyltransferase
GRK6 G protein-coupled receptor kinase 6
GSTM4 glutathione S-transferase mu 4
H2BFS H2B histone family, member S (pseudogene)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DMB major histocompatibility complex, class II, DM beta
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KHK ketohexokinase (fructokinase)
KIAA1109 KIAA1109
KIF2A kinesin heavy chain member 2A
KRIT1 KRIT1, ankyrin repeat containing
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC399491
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MCM9 minichromosome maintenance complex component 9
MRPL33 mitochondrial ribosomal protein L33
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTM1 myotubularin 1
MXD4 MAX dimerization protein 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCLN nicalin
NCOA3 nuclear receptor coactivator 3
NCS1 neuronal calcium sensor 1
NMT1 N-myristoyltransferase 1
NPPA natriuretic peptide A
PAPOLA poly(A) polymerase alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFA platelet-derived growth factor alpha polypeptide
PEMT phosphatidylethanolamine N-methyltransferase
PILRB paired immunoglobin-like type 2 receptor beta
PLCD1 phospholipase C, delta 1
POLI polymerase (DNA directed) iota
PTMA prothymosin, alpha
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB4B RAB4B, member RAS oncogene family
RANBP10 RAN binding protein 10
RBL1 retinoblastoma-like 1
RNF121 ring finger protein 121
RRBP1 ribosome binding protein 1
RWDD3 RWD domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG5 SMG5 nonsense mediated mRNA decay factor
STIP1 stress-induced phosphoprotein 1
SUB1 SUB1 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TMEM57 transmembrane protein 57
TPGS2 tubulin polyglutamylase complex subunit 2
TRA T cell receptor alpha locus
TRAC T cell receptor alpha constant
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSSC4 tumor suppressing subtransferable candidate 4
TTLL4 tubulin tyrosine ligase-like family member 4
UNC93B1 unc-93 homolog B1 (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
WDR46 WD repeat domain 46
WDR74 WD repeat domain 74
WSB1 WD repeat and SOCS box containing 1
WWC2 WW and C2 domain containing 2
ZEB2 zinc finger E-box binding homeobox 2
ZNF22 zinc finger protein 22
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD3 abhydrolase domain containing 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM15 ADAM metallopeptidase domain 15
ADAT1 adenosine deaminase, tRNA-specific 1
ADCY7 adenylate cyclase 7
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ALS2CL ALS2 C-terminal like
APOC4 apolipoprotein C-IV
ATAD2B ATPase family, AAA domain containing 2B
ATF3 activating transcription factor 3
ATG14 autophagy related 14
ATXN2 ataxin 2
BFAR bifunctional apoptosis regulator
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C14ORF159 chromosome 14 open reading frame 159
C5ORF22 chromosome 5 open reading frame 22
C8ORF60 chromosome 8 open reading frame 60
C9ORF40 chromosome 9 open reading frame 40
CCNE2 cyclin E2
CDC25B cell division cycle 25B
CEP170B centrosomal protein 170B
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CPA2 carboxypeptidase A2 (pancreatic)
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDIT4 DNA-damage-inducible transcript 4
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DOK2 docking protein 2, 56kDa
DOLPP1 dolichyldiphosphatase 1
DRAM1 DNA-damage regulated autophagy modulator 1
DSN1 DSN1, MIS12 kinetochore complex component
EDAR ectodysplasin A receptor
EVL Enah/Vasp-like
FAM222B family with sequence similarity 222, member B
FANCC Fanconi anemia, complementation group C
FANCE Fanconi anemia, complementation group E
FBXL14 F-box and leucine-rich repeat protein 14
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GABARAPL2 GABA(A) receptor-associated protein-like 2
GPR27 G protein-coupled receptor 27
GTF2A2 general transcription factor IIA, 2, 12kDa
HELLS helicase, lymphoid-specific
IL2RB interleukin 2 receptor, beta
INF2 inverted formin, FH2 and WH2 domain containing
KIAA0196 KIAA0196
KLF10 Kruppel-like factor 10
KLF7 Kruppel-like factor 7 (ubiquitous)
MAPK10 mitogen-activated protein kinase 10
MED23 mediator complex subunit 23
MFSD12 major facilitator superfamily domain containing 12
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR6 myotubularin related protein 6
MYLIP myosin regulatory light chain interacting protein
MYNN myoneurin
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NCF1C neutrophil cytosolic factor 1C pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNRC1 proline-rich nuclear receptor coactivator 1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PTPRE protein tyrosine phosphatase, receptor type, E
RAB20 RAB20, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RBBP5 retinoblastoma binding protein 5
RBM14 RNA binding motif protein 14
RUNX1-IT1 RUNX1 intronic transcript 1
S1PR4 sphingosine-1-phosphate receptor 4
SCAMP5 secretory carrier membrane protein 5
SERTAD3 SERTA domain containing 3
SETD1B SET domain containing 1B
SIRT1 sirtuin 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SREBF1 sterol regulatory element binding transcription factor 1
STAC SH3 and cysteine rich domain
TEX40 testis expressed 40
TRIM66 tripartite motif containing 66
TXLNA taxilin alpha
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC119B unc-119 homolog B (C. elegans)
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
USP6 ubiquitin specific peptidase 6
VAV1 vav 1 guanine nucleotide exchange factor
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
ZNF140 zinc finger protein 140
ZNF654 zinc finger protein 654
ZWINT ZW10 interacting kinetochore protein