isoconazole-2056 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the isoconazole-2056 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACOX3 acyl-CoA oxidase 3, pristanoyl
AKAP13 A kinase (PRKA) anchor protein 13
ANXA10 annexin A10
ARTN artemin
ATAT1 alpha tubulin acetyltransferase 1
ATP11A ATPase, class VI, type 11A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS9 Bardet-Biedl syndrome 9
C11ORF30 chromosome 11 open reading frame 30
C6ORF10 chromosome 6 open reading frame 10
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASZ1 castor zinc finger 1
CCKAR cholecystokinin A receptor
CEP72 centrosomal protein 72kDa
CLDN8 claudin 8
CSF1R colony stimulating factor 1 receptor
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK3 death-associated protein kinase 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT3 DNA-damage-inducible transcript 3
DHODH dihydroorotate dehydrogenase (quinone)
DSC2 desmocollin 2
DUSP1 dual specificity phosphatase 1
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
ETV1 ets variant 1
ETV5 ets variant 5
EXD3 exonuclease 3'-5' domain containing 3
FBN1 fibrillin 1
FCMR Fc fragment of IgM receptor
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GK3P glycerol kinase 3 pseudogene
GOLGA2 golgin A2
HIST1H4D histone cluster 1, H4d
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HOXC8 homeobox C8
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDI2-AS1 IDI2 antisense RNA 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL33R interleukin 33 receptor
INCENP inner centromere protein antigens 135/155kDa
ING4 inhibitor of growth family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRT17 keratin 17, type I
LIFR leukemia inhibitory factor receptor alpha
LPP LIM domain containing preferred translocation partner in lipoma
MACF1 microtubule-actin crosslinking factor 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4 microtubule-associated protein 4
MAPK11 mitogen-activated protein kinase 11
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MED28 mediator complex subunit 28
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTUS1 microtubule associated tumor suppressor 1
MYOZ3 myozenin 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPFFR1 neuropeptide FF receptor 1
OASL 2'-5'-oligoadenylate synthetase-like
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PF4 platelet factor 4
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTCH1 patched 1
PTGES prostaglandin E synthase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARG retinoic acid receptor, gamma
RGS4 regulator of G-protein signaling 4
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF122 ring finger protein 122
RRAD Ras-related associated with diabetes
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RYR1 ryanodine receptor 1 (skeletal)
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SMC1A structural maintenance of chromosomes 1A
SORBS2 sorbin and SH3 domain containing 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STEAP4 STEAP family member 4
TBX1 T-box 1
TCF15 transcription factor 15 (basic helix-loop-helix)
THBS3 thrombospondin 3
TMEM159 transmembrane protein 159
TMEM50B transmembrane protein 50B
TRIM29 tripartite motif containing 29
TSPAN9 tetraspanin 9
TTC9 tetratricopeptide repeat domain 9
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBED4 zinc finger, BED-type containing 4
ZEB1 zinc finger E-box binding homeobox 1
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ABHD11 abhydrolase domain containing 11
ACAD8 acyl-CoA dehydrogenase family, member 8
ACIN1 apoptotic chromatin condensation inducer 1
AGBL5 ATP/GTP binding protein-like 5
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANAPC2 anaphase promoting complex subunit 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGAP17 Rho GTPase activating protein 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASAP1-IT1 ASAP1 intronic transcript 1
ATP10D ATPase, class V, type 10D
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
ATXN2 ataxin 2
BCAS3 breast carcinoma amplified sequence 3
BCOR BCL6 corepressor
BDNF brain-derived neurotrophic factor
CASC3 cancer susceptibility candidate 3
CHPF chondroitin polymerizing factor
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COCH cochlin
CUL9 cullin 9
DESI1 desumoylating isopeptidase 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNMBP dynamin binding protein
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
ECSIT ECSIT signalling integrator
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EVPL envoplakin
FLCN folliculin
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GAMT guanidinoacetate N-methyltransferase
GLT8D2 glycosyltransferase 8 domain containing 2
GRWD1 glutamate-rich WD repeat containing 1
HAUS6 HAUS augmin-like complex, subunit 6
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IMPACT impact RWD domain protein
IP6K1 inositol hexakisphosphate kinase 1
ITM2C integral membrane protein 2C
JADE1 jade family PHD finger 1
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIF23 kinesin family member 23
KIFC1 kinesin family member C1
KLC2 kinesin light chain 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR6 lysophosphatidic acid receptor 6
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC8E leucine rich repeat containing 8 family, member E
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEH1 melanoma antigen family H1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK7 mitogen-activated protein kinase 7
MCRS1 microspherule protein 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED9 mediator complex subunit 9
MKS1 Meckel syndrome, type 1
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NDRG4 NDRG family member 4
NRSN2 neurensin 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PARD6A par-6 family cell polarity regulator alpha
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G15 phospholipase A2, group XV
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POR P450 (cytochrome) oxidoreductase
RBM14 RNA binding motif protein 14
RBM38 RNA binding motif protein 38
RUSC2 RUN and SH3 domain containing 2
SETMAR SET domain and mariner transposase fusion gene
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMAD7 SMAD family member 7
SNAP29 synaptosomal-associated protein, 29kDa
SNPH syntaphilin
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TACC3 transforming, acidic coiled-coil containing protein 3
TATDN2 TatD DNase domain containing 2
THEM6 thioesterase superfamily member 6
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMC5 transmembrane channel-like 5
TMEM2 transmembrane protein 2
UBQLN4 ubiquilin 4
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB48 zinc finger and BTB domain containing 48
ZC3H12A zinc finger CCCH-type containing 12A
ZNF177 zinc finger protein 177
ZNF324 zinc finger protein 324
ZNF787 zinc finger protein 787