| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the isoconazole-2218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF3 | activating transcription factor 3 |
| BDKRB2 | bradykinin receptor B2 |
| BMP8B | bone morphogenetic protein 8b |
| BTNL3 | butyrophilin-like 3 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD47 | CD47 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| COL1A1 | collagen, type I, alpha 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CTH | cystathionine gamma-lyase |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DLX2 | distal-less homeobox 2 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DUSP4 | dual specificity phosphatase 4 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPM6A | glycoprotein M6A |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INHBE | inhibin, beta E |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JUN | jun proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA1107 | KIAA1107 |
| KIFC3 | kinesin family member C3 |
| KIZ | kizuna centrosomal protein |
| KLHL20 | kelch-like family member 20 |
| KLHL29 | kelch-like family member 29 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LTB4R | leukotriene B4 receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MATN3 | matrilin 3 |
| MLXIP | MLX interacting protein |
| MYCNOS | MYCN opposite strand |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NDNF | neuron-derived neurotrophic factor |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUP188 | nucleoporin 188kDa |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PHF8 | PHD finger protein 8 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB33A | RAB33A, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBM5 | RNA binding motif protein 5 |
| REEP2 | receptor accessory protein 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RND1 | Rho family GTPase 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A8 | S100 calcium binding protein A8 |
| SERHL2 | serine hydrolase-like 2 |
| SH2B1 | SH2B adaptor protein 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TCF12 | transcription factor 12 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM209 | transmembrane protein 209 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALS2CL | ALS2 C-terminal like |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALML5 | calmodulin-like 5 |
| CD80 | CD80 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CLGN | calmegin |
| CORT | cortistatin |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNM1 | dynamin 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPPK1 | epiplakin 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETNK2 | ethanolamine kinase 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLRA1 | glycine receptor, alpha 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRPR | gastrin-releasing peptide receptor |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTM5 | glutathione S-transferase mu 5 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCFC1 | host cell factor C1 |
| HIST1H1D | histone cluster 1, H1d |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KRT15 | keratin 15, type I |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHX6 | LIM homeobox 6 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGEB2 | melanoma antigen family B2 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYOZ1 | myozenin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL10 | nucleolar protein 10 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCAN3 | RCAN family member 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF208 | ring finger protein 208 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| S100A9 | S100 calcium binding protein A9 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SDC3 | syndecan 3 |
| SETD1A | SET domain containing 1A |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRT6 | sirtuin 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STMN3 | stathmin-like 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM121 | transmembrane protein 121 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNS2 | tensin 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZIC3 | Zic family member 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF804A | zinc finger protein 804A |
| ZNF85 | zinc finger protein 85 |