isoconazole-5857 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the isoconazole-5857 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADGRL1 adhesion G protein-coupled receptor L1
ANP32A-IT1 ANP32A intronic transcript 1
ARC activity-regulated cytoskeleton-associated protein
ARRB2 arrestin, beta 2
ARTN artemin
ASIC3 acid sensing (proton gated) ion channel 3
ATF3 activating transcription factor 3
B9D1 B9 protein domain 1
BAHCC1 BAH domain and coiled-coil containing 1
BTBD18 BTB (POZ) domain containing 18
BTN3A2 butyrophilin, subfamily 3, member A2
C21ORF2 chromosome 21 open reading frame 2
CCDC85B coiled-coil domain containing 85B
CCNO cyclin O
CCPG1 cell cycle progression 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLSPN claspin
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
CSF1R colony stimulating factor 1 receptor
CXCL2 chemokine (C-X-C motif) ligand 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DBF4B DBF4 zinc finger B
DCTN2 dynactin 2 (p50)
DDIT4 DNA-damage-inducible transcript 4
DNAL4 dynein, axonemal, light chain 4
DST dystonin
EFCAB11 EF-hand calcium binding domain 11
EGR1 early growth response 1
ELMO2 engulfment and cell motility 2
ELN elastin
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPHB2 EPH receptor B2
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FAM214B family with sequence similarity 214, member B
FBXO40 F-box protein 40
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF21 fibroblast growth factor 21
FGF9 fibroblast growth factor 9
FKBP8 FK506 binding protein 8, 38kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GLDC glycine dehydrogenase (decarboxylating)
HDAC5 histone deacetylase 5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL33R interleukin 33 receptor
KLK13 kallikrein-related peptidase 13
KRIT1 KRIT1, ankyrin repeat containing
KRT6A keratin 6A, type II
LAT2 linker for activation of T cells family, member 2
LOC390998 ribosomal protein L10 pseudogene
LOXL3 lysyl oxidase-like 3
LRRK1 leucine-rich repeat kinase 1
MBNL2 muscleblind-like splicing regulator 2
MT1F metallothionein 1F
MUC1 mucin 1, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
MYRF myelin regulatory factor
NCAPH2 non-SMC condensin II complex, subunit H2
NCOA2 nuclear receptor coactivator 2
NEUROD6 neuronal differentiation 6
NRP2 neuropilin 2
NRXN3 neurexin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARM1 prostate androgen-regulated mucin-like protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXND1 plexin D1
PRDM1 PR domain containing 1, with ZNF domain
PTGES prostaglandin E synthase
PTK7 protein tyrosine kinase 7 (inactive)
PVT1 Pvt1 oncogene (non-protein coding)
RBM19 RNA binding motif protein 19
SARM1 sterile alpha and TIR motif containing 1
SHOX2 short stature homeobox 2
SIRT6 sirtuin 6
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
STAG3 stromal antigen 3
STK11 serine/threonine kinase 11
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBCD tubulin folding cofactor D
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TJAP1 tight junction associated protein 1 (peripheral)
TK2 thymidine kinase 2, mitochondrial
TMEM57 transmembrane protein 57
TMEM63A transmembrane protein 63A
TMEM8B transmembrane protein 8B
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZBTB22 zinc finger and BTB domain containing 22
ZMAT5 zinc finger, matrin-type 5
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADGRG2 adhesion G protein-coupled receptor G2
ARHGAP11A Rho GTPase activating protein 11A
BPHL biphenyl hydrolase-like (serine hydrolase)
C1ORF115 chromosome 1 open reading frame 115
C1ORF56 chromosome 1 open reading frame 56
CBR4 carbonyl reductase 4
CCNT1 cyclin T1
CDC45 cell division cycle 45
CGREF1 cell growth regulator with EF-hand domain 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CTNNBIP1 catenin, beta interacting protein 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EIF5A2 eukaryotic translation initiation factor 5A2
EML4 echinoderm microtubule associated protein like 4
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FEM1C fem-1 homolog c (C. elegans)
FOXC1 forkhead box C1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GDE1 glycerophosphodiester phosphodiesterase 1
GLT8D2 glycosyltransferase 8 domain containing 2
GPHN gephyrin
GPR137B G protein-coupled receptor 137B
GSR glutathione reductase
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HHEX hematopoietically expressed homeobox
HIST1H2AJ histone cluster 1, H2aj
HIST1H3G histone cluster 1, H3g
INCENP inner centromere protein antigens 135/155kDa
IP6K2 inositol hexakisphosphate kinase 2
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2C integral membrane protein 2C
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIF23 kinesin family member 23
KLHL26 kelch-like family member 26
KRT75 keratin 75, type II
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LRRC37A3 leucine rich repeat containing 37, member A3
MPP1 membrane protein, palmitoylated 1, 55kDa
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAG18 NAG18 mRNA
NCF2 neutrophil cytosolic factor 2
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PSAT1 phosphoserine aminotransferase 1
RAB23 RAB23, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RGCC regulator of cell cycle
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROGDI rogdi homolog (Drosophila)
SCEL sciellin
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SELENBP1 selenium binding protein 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPAG4 sperm associated antigen 4
SYNPO synaptopodin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TMEM156 transmembrane protein 156
TMEM230 transmembrane protein 230
TMEM8A transmembrane protein 8A
TRAIP TRAF interacting protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBL4A ubiquitin-like 4A
URM1 ubiquitin related modifier 1
UROS uroporphyrinogen III synthase
YIPF5 Yip1 domain family, member 5
ZNF32 zinc finger protein 32
ZNF33B zinc finger protein 33B
ZNF586 zinc finger protein 586
ZWILCH zwilch kinetochore protein