| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the isoconazole-7211 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK2 | adenylate kinase 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATF3 | activating transcription factor 3 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTBD7 | BTB (POZ) domain containing 7 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CADM4 | cell adhesion molecule 4 |
| CCKBR | cholecystokinin B receptor |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| CRY2 | cryptochrome circadian clock 2 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DPYS | dihydropyrimidinase |
| DSC3 | desmocollin 3 |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| DUSP1 | dual specificity phosphatase 1 |
| EDNRB | endothelin receptor type B |
| EGR1 | early growth response 1 |
| FAM155A | family with sequence similarity 155, member A |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| FZD9 | frizzled class receptor 9 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HRH2 | histamine receptor H2 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT122 | intraflagellar transport 122 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| ITM2C | integral membrane protein 2C |
| JUN | jun proto-oncogene |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1A | microtubule-associated protein 1A |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble |
| MPZL1 | myelin protein zero-like 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| MZF1 | myeloid zinc finger 1 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NDRG2 | NDRG family member 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PARVB | parvin, beta |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PCGF3 | polycomb group ring finger 3 |
| PDE11A | phosphodiesterase 11A |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNLIPRP2 | pancreatic lipase-related protein 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RUNX1 | runt-related transcription factor 1 |
| SERHL2 | serine hydrolase-like 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBX6 | T-box 6 |
| TEF | thyrotrophic embryonic factor |
| TMEM212 | transmembrane protein 212 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF222 | zinc finger protein 222 |
| ZNF286A | zinc finger protein 286A |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ABHD10 | abhydrolase domain containing 10 |
| ACVR1 | activin A receptor, type I |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AR | androgen receptor |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BCORL1 | BCL6 corepressor-like 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5 | complement component 5 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CENPJ | centromere protein J |
| CHMP6 | charged multivesicular body protein 6 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXO31 | F-box protein 31 |
| FZD2 | frizzled class receptor 2 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| HEATR3 | HEAT repeat containing 3 |
| HIST1H1D | histone cluster 1, H1d |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KRT8P12 | keratin 8 pseudogene 12 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NABP2 | nucleic acid binding protein 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NECAP2 | NECAP endocytosis associated 2 |
| NLK | nemo-like kinase |
| NRBF2 | nuclear receptor binding factor 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLH | polymerase (DNA directed), eta |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTK6 | protein tyrosine kinase 6 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RBL1 | retinoblastoma-like 1 |
| REEP4 | receptor accessory protein 4 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| ROM1 | retinal outer segment membrane protein 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SAMHD1 | SAM domain and HD domain 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGMS1 | sphingomyelin synthase 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SIK1 | salt-inducible kinase 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOAT1 | sterol O-acyltransferase 1 |
| SPANXC | SPANX family, member C |
| SPATA2L | spermatogenesis associated 2-like |
| STXBP1 | syntaxin binding protein 1 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TEP1 | telomerase-associated protein 1 |
| TRAIP | TRAF interacting protein |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UNKL | unkempt family zinc finger-like |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF205 | zinc finger protein 205 |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |
| ZNF813 | zinc finger protein 813 |