isocorydine-2780 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the isocorydine-2780 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD3A ATPase family, AAA domain containing 3A
ATF7IP activating transcription factor 7 interacting protein
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAX BCL2-associated X protein
BBS9 Bardet-Biedl syndrome 9
C11ORF30 chromosome 11 open reading frame 30
C1ORF61 chromosome 1 open reading frame 61
C1ORF95 chromosome 1 open reading frame 95
CAPN5 calpain 5
CD58 CD58 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLDN17 claudin 17
COL19A1 collagen, type XIX, alpha 1
COL6A1 collagen, type VI, alpha 1
DMRT1 doublesex and mab-3 related transcription factor 1
DPYSL4 dihydropyrimidinase-like 4
EHD1 EH-domain containing 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FADS2 fatty acid desaturase 2
FAM46C family with sequence similarity 46, member C
FGF12 fibroblast growth factor 12
FRMD4A FERM domain containing 4A
GMPR guanosine monophosphate reductase
GNRH2 gonadotropin-releasing hormone 2
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H4E histone cluster 1, H4e
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA10 homeobox A10
HOXA6 homeobox A6
HOXB7 homeobox B7
IL1B interleukin 1, beta
IL23A interleukin 23, alpha subunit p19
IL6R interleukin 6 receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LRRC61 leucine rich repeat containing 61
MAGOH2P mago-nashi homolog 2, pseudogene
MARK4 MAP/microtubule affinity-regulating kinase 4
MMP25 matrix metallopeptidase 25
MPPE1 metallophosphoesterase 1
MST1R macrophage stimulating 1 receptor
NPIPB15 nuclear pore complex interacting protein family, member B15
NR4A1 nuclear receptor subfamily 4, group A, member 1
OBSL1 obscurin-like 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE10A phosphodiesterase 10A
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEAK1 pseudopodium-enriched atypical kinase 1
PGBD5 piggyBac transposable element derived 5
PLAGL2 pleiomorphic adenoma gene-like 2
PLCH1 phospholipase C, eta 1
PLLP plasmolipin
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSD4 pleckstrin and Sec7 domain containing 4
PTOV1 prostate tumor overexpressed 1
RARA retinoic acid receptor, alpha
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRBP1 ribosome binding protein 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SH2D3A SH2 domain containing 3A
SKIL SKI-like proto-oncogene
SLC17A2 solute carrier family 17, member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SRRT serrate, RNA effector molecule
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SUN1 Sad1 and UNC84 domain containing 1
TAPBP TAP binding protein (tapasin)
TBL1Y transducin (beta)-like 1, Y-linked
TFR2 transferrin receptor 2
THBS4 thrombospondin 4
THOC5 THO complex 5
TK2 thymidine kinase 2, mitochondrial
TLE2 transducin-like enhancer of split 2
TOP3B topoisomerase (DNA) III beta
TUBA3D tubulin, alpha 3d
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFA vascular endothelial growth factor A
WDR1 WD repeat domain 1
WDTC1 WD and tetratricopeptide repeats 1
ZER1 zyg-11 related, cell cycle regulator
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFF4 AF4/FMR2 family, member 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMPD1 adenosine monophosphate deaminase 1
AOX1 aldehyde oxidase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
BAG4 BCL2-associated athanogene 4
BTBD7 BTB (POZ) domain containing 7
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC68 coiled-coil domain containing 68
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
CLCN6 chloride channel, voltage-sensitive 6
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP13 dual specificity phosphatase 13
EFNA1 ephrin-A1
EXOC5 exocyst complex component 5
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FAM212B family with sequence similarity 212, member B
FER fer (fps/fes related) tyrosine kinase
FOXC1 forkhead box C1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR87 G protein-coupled receptor 87
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFT22 intraflagellar transport 22
KDM7A lysine (K)-specific demethylase 7A
KIAA1107 KIAA1107
KLF3 Kruppel-like factor 3 (basic)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LRP3 low density lipoprotein receptor-related protein 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MATK megakaryocyte-associated tyrosine kinase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MNX1 motor neuron and pancreas homeobox 1
MPI mannose phosphate isomerase
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
PARPBP PARP1 binding protein
PGPEP1 pyroglutamyl-peptidase I
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPT2 palmitoyl-protein thioesterase 2
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRPF39 pre-mRNA processing factor 39
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QSER1 glutamine and serine rich 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCOR3 REST corepressor 3
RGS19 regulator of G-protein signaling 19
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUNDC3B RUN domain containing 3B
SCML2 sex comb on midleg-like 2 (Drosophila)
SCRN3 secernin 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNIP1 Smad nuclear interacting protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D19 TBC1 domain family, member 19
TIPRL TOR signaling pathway regulator
UBXN6 UBX domain protein 6
VASH2 vasohibin 2
ZBTB44 zinc finger and BTB domain containing 44
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP69B ZFP69 zinc finger protein B
ZNF34 zinc finger protein 34
ZNF532 zinc finger protein 532
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZSCAN2 zinc finger and SCAN domain containing 2
ZSCAN31 zinc finger and SCAN domain containing 31