isoetarine-3451 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the isoetarine-3451 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAM28 ADAM metallopeptidase domain 28
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASIC1 acid sensing (proton gated) ion channel 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B9D1 B9 protein domain 1
C14ORF79 chromosome 14 open reading frame 79
C2ORF27A chromosome 2 open reading frame 27A
CABIN1 calcineurin binding protein 1
CABP2 calcium binding protein 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALD1 caldesmon 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD82 CD82 molecule
COL11A2 collagen, type XI, alpha 2
COL5A1 collagen, type V, alpha 1
DCAF15 DDB1 and CUL4 associated factor 15
DSC1 desmocollin 1
DTNA dystrobrevin, alpha
DUSP2 dual specificity phosphatase 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPS8L1 EPS8-like 1
FGF18 fibroblast growth factor 18
FGF5 fibroblast growth factor 5
FLJ11710 uncharacterized protein FLJ11710
FOSL2 FOS-like antigen 2
GCKR glucokinase (hexokinase 4) regulator
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GHRHR growth hormone releasing hormone receptor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GOLGA4 golgin A4
GRK5 G protein-coupled receptor kinase 5
GSTM4 glutathione S-transferase mu 4
GTDC1 glycosyltransferase-like domain containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
JADE2 jade family PHD finger 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLHL1 kelch-like family member 1
KRT17 keratin 17, type I
KSR1 kinase suppressor of ras 1
LAMB3 laminin, beta 3
LOX lysyl oxidase
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MPPE1 metallophosphoesterase 1
MYL10 myosin, light chain 10, regulatory
NKX3-1 NK3 homeobox 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHB13 protocadherin beta 13
PDLIM7 PDZ and LIM domain 7 (enigma)
PICK1 protein interacting with PRKCA 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSIP1 PC4 and SFRS1 interacting protein 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RIMS3 regulating synaptic membrane exocytosis 3
RNFT1 ring finger protein, transmembrane 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SFTPB surfactant protein B
SGSM3 small G protein signaling modulator 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SRSF11 serine/arginine-rich splicing factor 11
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TBX6 T-box 6
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM63A transmembrane protein 63A
TWISTNB TWIST neighbor
UST uronyl-2-sulfotransferase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFB vascular endothelial growth factor B
VLDLR very low density lipoprotein receptor
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNK1 WNK lysine deficient protein kinase 1
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein
ZNF280A zinc finger protein 280A
ZNF350 zinc finger protein 350
ZNF428 zinc finger protein 428
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASPHD1 aspartate beta-hydroxylase domain containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
C2ORF54 chromosome 2 open reading frame 54
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCP110 centriolar coiled coil protein 110kDa
CD151 CD151 molecule (Raph blood group)
CGA glycoprotein hormones, alpha polypeptide
CPTP ceramide-1-phosphate transfer protein
CRY2 cryptochrome circadian clock 2
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DDIT3 DNA-damage-inducible transcript 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EML4 echinoderm microtubule associated protein like 4
F3 coagulation factor III (thromboplastin, tissue factor)
FA2H fatty acid 2-hydroxylase
FAM53B family with sequence similarity 53, member B
FAM86C1 family with sequence similarity 86, member C1
FANCC Fanconi anemia, complementation group C
FRK fyn-related Src family tyrosine kinase
GLCE glucuronic acid epimerase
GPR143 G protein-coupled receptor 143
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
IPO8 importin 8
KATNBL1 katanin p80 subunit B-like 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0430 KIAA0430
KIF13B kinesin family member 13B
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIG4 ligase IV, DNA, ATP-dependent
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
MDN1 MDN1, midasin homolog (yeast)
MRPL44 mitochondrial ribosomal protein L44
MSMB microseminoprotein, beta-
MTM1 myotubularin 1
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
P3H1 prolyl 3-hydroxylase 1
PARD6A par-6 family cell polarity regulator alpha
PGAP1 post-GPI attachment to proteins 1
PGM1 phosphoglucomutase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD3 phospholipase D family, member 3
PODXL podocalyxin-like
POLH polymerase (DNA directed), eta
PRICKLE3 prickle homolog 3 (Drosophila)
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB30 RAB30, member RAS oncogene family
RBM41 RNA binding motif protein 41
REPS2 RALBP1 associated Eps domain containing 2
RNFT2 ring finger protein, transmembrane 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIRT2 sirtuin 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
STK25 serine/threonine kinase 25
STRN striatin, calmodulin binding protein
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SYCP2 synaptonemal complex protein 2
SYNGR3 synaptogyrin 3
TARP TCR gamma alternate reading frame protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBL3 transducin (beta)-like 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM104 transmembrane protein 104
TMOD3 tropomodulin 3 (ubiquitous)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
WDR33 WD repeat domain 33
XYLT2 xylosyltransferase II
YBX2 Y box binding protein 2
YIPF3 Yip1 domain family, member 3
ZFHX3 zinc finger homeobox 3
ZNF211 zinc finger protein 211
ZNF480 zinc finger protein 480