| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the isoetarine-5812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACACB | acetyl-CoA carboxylase beta |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AQP3 | aquaporin 3 (Gill blood group) |
| BCL2A1 | BCL2-related protein A1 |
| BMP2 | bone morphogenetic protein 2 |
| CBX8 | chromobox homolog 8 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDON | cell adhesion associated, oncogene regulated |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHEK2 | checkpoint kinase 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CREM | cAMP responsive element modulator |
| CRYBA2 | crystallin, beta A2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTH | cystathionine gamma-lyase |
| CYHR1 | cysteine/histidine-rich 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOCK9 | dedicator of cytokinesis 9 |
| DSG3 | desmoglein 3 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EGR2 | early growth response 2 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GPATCH3 | G patch domain containing 3 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| IFNA14 | interferon, alpha 14 |
| IFT122 | intraflagellar transport 122 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| IL33R | interleukin 33 receptor |
| ING1 | inhibitor of growth family, member 1 |
| INO80B | INO80 complex subunit B |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRGQ | immunity-related GTPase family, Q |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP1A | microtubule-associated protein 1A |
| MAP7 | microtubule-associated protein 7 |
| MFN2 | mitofusin 2 |
| NBEAL2 | neurobeachin-like 2 |
| NGLY1 | N-glycanase 1 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| NUP160 | nucleoporin 160kDa |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSBP2 | oxysterol binding protein 2 |
| OSMR | oncostatin M receptor |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEX10 | peroxisomal biogenesis factor 10 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PHF7 | PHD finger protein 7 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTGES | prostaglandin E synthase |
| PTHLH | parathyroid hormone-like hormone |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SIRT3 | sirtuin 3 |
| SIRT5 | sirtuin 5 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMOX | spermine oxidase |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| STC1 | stanniocalcin 1 |
| SYN2 | synapsin II |
| TAGLN3 | transgelin 3 |
| TEX40 | testis expressed 40 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TFF1 | trefoil factor 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLE2 | transducin-like enhancer of split 2 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBTD1 | ubiquitin domain containing 1 |
| VGF | VGF nerve growth factor inducible |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZNF324 | zinc finger protein 324 |
| ZNF529 | zinc finger protein 529 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADORA2B | adenosine A2b receptor |
| ADRB2 | adrenoceptor beta 2, surface |
| AFAP1 | actin filament associated protein 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APOL6 | apolipoprotein L, 6 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ATG2B | autophagy related 2B |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC69 | coiled-coil domain containing 69 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEP112 | centrosomal protein 112kDa |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COQ6 | coenzyme Q6 monooxygenase |
| CRIP2 | cysteine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC8 | excision repair cross-complementation group 8 |
| EXOC5 | exocyst complex component 5 |
| FOXC1 | forkhead box C1 |
| G0S2 | G0/G1 switch 2 |
| GALE | UDP-galactose-4-epimerase |
| GBX2 | gastrulation brain homeobox 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BI | histone cluster 1, H2bi |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLX | H2.0-like homeobox |
| HYI | hydroxypyruvate isomerase (putative) |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL15RA | interleukin 15 receptor, alpha |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KIAA0894 | KIAA0894 protein |
| KLF2 | Kruppel-like factor 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL12 | kelch-like family member 12 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHFP | lipoma HMGIC fusion partner |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRC16A | leucine rich repeat containing 16A |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCRS1 | microspherule protein 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYL5 | myosin, light chain 5, regulatory |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PLCD1 | phospholipase C, delta 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRAME | preferentially expressed antigen in melanoma |
| PTX3 | pentraxin 3, long |
| RCOR3 | REST corepressor 3 |
| RFX7 | regulatory factor X, 7 |
| RNF25 | ring finger protein 25 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SNX15 | sorting nexin 15 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| STAC | SH3 and cysteine rich domain |
| STBD1 | starch binding domain 1 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TENM4 | teneurin transmembrane protein 4 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| WDR18 | WD repeat domain 18 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |