isoetarine-7170 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the isoetarine-7170 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADAM23 ADAM metallopeptidase domain 23
ADCY9 adenylate cyclase 9
AKAP7 A kinase (PRKA) anchor protein 7
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAG4 BCL2-associated athanogene 4
BIRC7 baculoviral IAP repeat containing 7
BLVRA biliverdin reductase A
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CC2D1A coiled-coil and C2 domain containing 1A
CD302 CD302 molecule
CDH8 cadherin 8, type 2
CDK3 cyclin-dependent kinase 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLASP2 cytoplasmic linker associated protein 2
COPE coatomer protein complex, subunit epsilon
CTNNBIP1 catenin, beta interacting protein 1
CTNS cystinosin, lysosomal cystine transporter
DCTN1 dynactin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSTYK dual serine/threonine and tyrosine protein kinase
DVL2 dishevelled segment polarity protein 2
ERCC4 excision repair cross-complementation group 4
EVA1B eva-1 homolog B (C. elegans)
FAM120C family with sequence similarity 120C
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
GADD45G growth arrest and DNA-damage-inducible, gamma
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GPR137 G protein-coupled receptor 137
GPR153 G protein-coupled receptor 153
GSK3A glycogen synthase kinase 3 alpha
HAPLN1 hyaluronan and proteoglycan link protein 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HNMT histamine N-methyltransferase
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFT54 intraflagellar transport 54
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KRIT1 KRIT1, ankyrin repeat containing
LIG4 ligase IV, DNA, ATP-dependent
LOC257152 uncharacterized LOC257152
LOC399491
LYPD1 LY6/PLAUR domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MIIP migration and invasion inhibitory protein
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MPPE1 metallophosphoesterase 1
MRPS18C mitochondrial ribosomal protein S18C
NAV2 neuron navigator 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NIPAL2 NIPA-like domain containing 2
NOP16 NOP16 nucleolar protein
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PGP phosphoglycolate phosphatase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
QKI QKI, KH domain containing, RNA binding
RFTN1 raftlin, lipid raft linker 1
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RHOQ ras homolog family member Q
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAFB2 scaffold attachment factor B2
SAMD9 sterile alpha motif domain containing 9
SFXN3 sideroflexin 3
SKIL SKI-like proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOGA1 suppressor of glucose, autophagy associated 1
SP100 SP100 nuclear antigen
SPRYD7 SPRY domain containing 7
SRI sorcin
TGFA transforming growth factor, alpha
TMEM120B transmembrane protein 120B
TMEM19 transmembrane protein 19
TMEM63A transmembrane protein 63A
TREX1 three prime repair exonuclease 1
TRIO trio Rho guanine nucleotide exchange factor
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TXNL4A thioredoxin-like 4A
WSCD1 WSC domain containing 1
WWOX WW domain containing oxidoreductase
ZBTB7A zinc finger and BTB domain containing 7A
ZNF528 zinc finger protein 528
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
ARL15 ADP-ribosylation factor-like 15
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBC3 BCL2 binding component 3
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
BPGM 2,3-bisphosphoglycerate mutase
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C21ORF91 chromosome 21 open reading frame 91
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CDK9 cyclin-dependent kinase 9
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COCH cochlin
CORO2A coronin, actin binding protein, 2A
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRLF1 cytokine receptor-like factor 1
CUEDC1 CUE domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DSPP dentin sialophosphoprotein
EAF2 ELL associated factor 2
ENO2 enolase 2 (gamma, neuronal)
EPHA2 EPH receptor A2
FAM188A family with sequence similarity 188, member A
FAM57A family with sequence similarity 57, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGGY FGGY carbohydrate kinase domain containing
FKBP10 FK506 binding protein 10, 65 kDa
FOXM1 forkhead box M1
GAN gigaxonin
GLCE glucuronic acid epimerase
GPR87 G protein-coupled receptor 87
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HSPA2 heat shock 70kDa protein 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO8 importin 8
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KREMEN2 kringle containing transmembrane protein 2
KRT86 keratin 86, type II
LOXL1 lysyl oxidase-like 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAST3 microtubule associated serine/threonine kinase 3
MEIS1 Meis homeobox 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NDRG1 N-myc downstream regulated 1
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
PC pyruvate carboxylase
PLA2G15 phospholipase A2, group XV
PODXL podocalyxin-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RPAP1 RNA polymerase II associated protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAV1 salvador family WW domain containing protein 1
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SERTAD3 SERTA domain containing 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35F6 solute carrier family 35, member F6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX3 SRY (sex determining region Y)-box 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3 stromal antigen 3
TESK2 testis-specific kinase 2
TLN1 talin 1
TMEM51 transmembrane protein 51
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS2 tensin 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM25 tripartite motif containing 25
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV1 vav 1 guanine nucleotide exchange factor
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF212 zinc finger protein 212
ZNF35 zinc finger protein 35
ZNF668 zinc finger protein 668
ZNF701 zinc finger protein 701
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2