isoflupredone-1832 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the isoflupredone-1832 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AHNAK AHNAK nucleoprotein
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C1 aldo-keto reductase family 1, member C1
ANGPTL4 angiopoietin-like 4
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOL6 apolipoprotein L, 6
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAX BCL2-associated X protein
CA12 carbonic anhydrase XII
CCL20 chemokine (C-C motif) ligand 20
CDV3 CDV3 homolog (mouse)
CHKA choline kinase alpha
CPE carboxypeptidase E
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTBS chitobiase, di-N-acetyl-
CTSZ cathepsin Z
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
DAZAP2 DAZ associated protein 2
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DUSP1 dual specificity phosphatase 1
EFNB2 ephrin-B2
ELF1 E74-like factor 1 (ets domain transcription factor)
ESR1 estrogen receptor 1
FAT4 FAT atypical cadherin 4
FDX1 ferredoxin 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FSCN1 fascin actin-bundling protein 1
GUSBP3 glucuronidase, beta pseudogene 3
H1F0 H1 histone family, member 0
HEATR6 HEAT repeat containing 6
HIRA histone cell cycle regulator
HNMT histamine N-methyltransferase
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IL6R interleukin 6 receptor
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
KIDINS220 kinase D-interacting substrate, 220kDa
KLF6 Kruppel-like factor 6
KLHL9 kelch-like family member 9
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LIN7C lin-7 homolog C (C. elegans)
LMNB1 lamin B1
MAT2A methionine adenosyltransferase II, alpha
MAX MYC associated factor X
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED6 mediator complex subunit 6
MEX3D mex-3 RNA binding family member D
MPDZ multiple PDZ domain protein
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MTAP methylthioadenosine phosphorylase
NAV2 neuron navigator 2
NEBL nebulette
NNMT nicotinamide N-methyltransferase
NNT nicotinamide nucleotide transhydrogenase
NOTCH2 notch 2
NREP neuronal regeneration related protein
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORAI2 ORAI calcium release-activated calcium modulator 2
PAPOLA poly(A) polymerase alpha
PER1 period circadian clock 1
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTGES prostaglandin E synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RDX radixin
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL23AP7 ribosomal protein L23a pseudogene 7
RSRP1 arginine/serine-rich protein 1
SERBP1 SERPINE1 mRNA binding protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNAI2 snail family zinc finger 2
SQLE squalene epoxidase
SRRM2 serine/arginine repetitive matrix 2
STOM stomatin
TAZ tafazzin
TLR2 toll-like receptor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM254 transmembrane protein 254
TNIK TRAF2 and NCK interacting kinase
TSPAN3 tetraspanin 3
TUBA3C tubulin, alpha 3c
USP34 ubiquitin specific peptidase 34
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZFYVE21 zinc finger, FYVE domain containing 21
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF358 zinc finger protein 358
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASTE1 asteroid homolog 1 (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP15 bone morphogenetic protein 15
C6ORF47 chromosome 6 open reading frame 47
C7ORF43 chromosome 7 open reading frame 43
CCDC94 coiled-coil domain containing 94
CCRL2 chemokine (C-C motif) receptor-like 2
CGREF1 cell growth regulator with EF-hand domain 1
CHPF chondroitin polymerizing factor
CLCN6 chloride channel, voltage-sensitive 6
CLDN14 claudin 14
CNTLN centlein, centrosomal protein
CTSF cathepsin F
CTSK cathepsin K
DNMBP dynamin binding protein
EN2 engrailed homeobox 2
ESM1 endothelial cell-specific molecule 1
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GBX2 gastrulation brain homeobox 2
GMIP GEM interacting protein
GPR1 G protein-coupled receptor 1
GRAMD1C GRAM domain containing 1C
HLX H2.0-like homeobox
HOXA2 homeobox A2
HYAL3 hyaluronoglucosaminidase 3
IFI27 interferon, alpha-inducible protein 27
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL24 interleukin 24
IL7R interleukin 7 receptor
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM5C lysine (K)-specific demethylase 5C
KIFC3 kinesin family member C3
KLHL36 kelch-like family member 36
KRT81 keratin 81, type II
LRP5L low density lipoprotein receptor-related protein 5-like
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
MITF microphthalmia-associated transcription factor
MOSPD3 motile sperm domain containing 3
MRPL52 mitochondrial ribosomal protein L52
NT5M 5',3'-nucleotidase, mitochondrial
NUAK1 NUAK family, SNF1-like kinase, 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ODF2 outer dense fiber of sperm tails 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFRL platelet-derived growth factor receptor-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAU plasminogen activator, urokinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTTG3P pituitary tumor-transforming 3, pseudogene
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBMS3 RNA binding motif, single stranded interacting protein 3
RIN1 Ras and Rab interactor 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPL21 ribosomal protein L21
RPL8 ribosomal protein L8
RPS24 ribosomal protein S24
RPS27 ribosomal protein S27
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D2A SH2 domain containing 2A
SMA4 glucuronidase, beta pseudogene
SMAD7 SMAD family member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TKFC triokinase/FMN cyclase
TMC7 transmembrane channel-like 7
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPST1 tyrosylprotein sulfotransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D4 TSC22 domain family, member 4
TUBA1C tubulin, alpha 1c
UNC119 unc-119 homolog (C. elegans)
URM1 ubiquitin related modifier 1
USP19 ubiquitin specific peptidase 19
VEZT vezatin, adherens junctions transmembrane protein
ZBTB22 zinc finger and BTB domain containing 22
ZMAT5 zinc finger, matrin-type 5
ZNF747 zinc finger protein 747
ZNF85 zinc finger protein 85
ZNF862 zinc finger protein 862
ZSCAN16 zinc finger and SCAN domain containing 16