| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the isometheptene-3145 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANGPTL2 | angiopoietin-like 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BLVRB | biliverdin reductase B |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CABP2 | calcium binding protein 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC71 | coiled-coil domain containing 71 |
| CD6 | CD6 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLDN3 | claudin 3 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CTSZ | cathepsin Z |
| DCAKD | dephospho-CoA kinase domain containing |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENG | endoglin |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| F12 | coagulation factor XII (Hageman factor) |
| FAM149A | family with sequence similarity 149, member A |
| FGF23 | fibroblast growth factor 23 |
| FOSL2 | FOS-like antigen 2 |
| FRMD8 | FERM domain containing 8 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAP43 | growth associated protein 43 |
| GATA4 | GATA binding protein 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GOLGA8A | golgin A8 family, member A |
| GPR132 | G protein-coupled receptor 132 |
| GPR21 | G protein-coupled receptor 21 |
| GSPT1 | G1 to S phase transition 1 |
| GUCY2F | guanylate cyclase 2F, retinal |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HOXA10 | homeobox A10 |
| HOXC8 | homeobox C8 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTRA1 | HtrA serine peptidase 1 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IL1A | interleukin 1, alpha |
| IL1RN | interleukin 1 receptor antagonist |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| KHK | ketohexokinase (fructokinase) |
| KIAA1024 | KIAA1024 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL22 | kelch-like family member 22 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MMP25 | matrix metallopeptidase 25 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTMR3 | myotubularin related protein 3 |
| MUC8 | mucin 8 |
| MXD1 | MAX dimerization protein 1 |
| MXD4 | MAX dimerization protein 4 |
| MYOZ2 | myozenin 2 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCBP4 | poly(rC) binding protein 4 |
| PDLIM5 | PDZ and LIM domain 5 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIRT3 | sirtuin 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYN3 | synapsin III |
| TGFB1 | transforming growth factor, beta 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLN2 | talin 2 |
| TNC | tenascin C |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM10 | tripartite motif containing 10 |
| UROD | uroporphyrinogen decarboxylase |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF362 | zinc finger protein 362 |
| ZNF407 | zinc finger protein 407 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ANKRD55 | ankyrin repeat domain 55 |
| APH1B | APH1B gamma secretase subunit |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARMC7 | armadillo repeat containing 7 |
| AXIN1 | axin 1 |
| BEST1 | bestrophin 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CD1D | CD1d molecule |
| CD34 | CD34 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLEC2D | C-type lectin domain family 2, member D |
| CNTN1 | contactin 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CPNE1 | copine I |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EHD3 | EH-domain containing 3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM53B | family with sequence similarity 53, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCHO1 | FCH domain only 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXC1 | forkhead box C1 |
| FOXO4 | forkhead box O4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA14 | interferon, alpha 14 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIAA0754 | KIAA0754 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOSPD3 | motile sperm domain containing 3 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCD1 | phospholipase C, delta 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRF1 | perforin 1 (pore forming protein) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF122 | ring finger protein 122 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI1 | snail family zinc finger 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP140 | SP140 nuclear body protein |
| SP4 | Sp4 transcription factor |
| SPATA20 | spermatogenesis associated 20 |
| ST5 | suppression of tumorigenicity 5 |
| SYTL2 | synaptotagmin-like 2 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TMEM212 | transmembrane protein 212 |
| TMEM242 | transmembrane protein 242 |
| TMEM246 | transmembrane protein 246 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRAF1 | TNF receptor-associated factor 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBTD1 | ubiquitin domain containing 1 |
| VEGFC | vascular endothelial growth factor C |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XAB2 | XPA binding protein 2 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF778 | zinc finger protein 778 |
