| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the isometheptene-5502 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| AFF1 | AF4/FMR2 family, member 1 |
| APC | adenomatous polyposis coli |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARTN | artemin |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP8A | bone morphogenetic protein 8a |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCNT2 | cyclin T2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFAP45 | cilia and flagella associated protein 45 |
| CLDN15 | claudin 15 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CLTA | clathrin, light chain A |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DENND3 | DENN/MADD domain containing 3 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DRD2 | dopamine receptor D2 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| EXOC7 | exocyst complex component 7 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FBXO21 | F-box protein 21 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF13 | fibroblast growth factor 13 |
| FH | fumarate hydratase |
| FKBPL | FK506 binding protein like |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GOLGA8A | golgin A8 family, member A |
| GPC4 | glypican 4 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HAP1 | huntingtin-associated protein 1 |
| HIST1H1D | histone cluster 1, H1d |
| HNMT | histamine N-methyltransferase |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA1644 | KIAA1644 |
| LMF1 | lipase maturation factor 1 |
| LMO7 | LIM domain 7 |
| LOC647070 | uncharacterized LOC647070 |
| LRRC61 | leucine rich repeat containing 61 |
| LUZP1 | leucine zipper protein 1 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYOF | myoferlin |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PCDHB3 | protocadherin beta 3 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POU5F1B | POU class 5 homeobox 1B |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRLR | prolactin receptor |
| PRPF31 | pre-mRNA processing factor 31 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A2 | S100 calcium binding protein A2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNX13 | sorting nexin 13 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STRN3 | striatin, calmodulin binding protein 3 |
| STX2 | syntaxin 2 |
| TBX2 | T-box 2 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TK1 | thymidine kinase 1, soluble |
| TMEM209 | transmembrane protein 209 |
| TRIM21 | tripartite motif containing 21 |
| VNN2 | vanin 2 |
| ZNF286A | zinc finger protein 286A |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AFF4 | AF4/FMR2 family, member 4 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5 | complement component 5 |
| CLEC4E | C-type lectin domain family 4, member E |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRLF1 | cytokine receptor-like factor 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK1 | dedicator of cytokinesis 1 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM155A | family with sequence similarity 155, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOLGA8B | golgin A8 family, member B |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H3B | histone cluster 1, H3b |
| IL17RA | interleukin 17 receptor A |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF1 | interferon regulatory factor 1 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KRT13 | keratin 13, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHX1 | LIM homeobox 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOXL3 | lysyl oxidase-like 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MED15 | mediator complex subunit 15 |
| MUC3A | mucin 3A, cell surface associated |
| NAG18 | NAG18 mRNA |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOL12 | nucleolar protein 12 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| ONECUT2 | one cut homeobox 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RECQL4 | RecQ protein-like 4 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF43 | ring finger protein 43 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SETD1A | SET domain containing 1A |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TLR5 | toll-like receptor 5 |
| TMEM183A | transmembrane protein 183A |
| TMEM51 | transmembrane protein 51 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TWF2 | twinfilin actin binding protein 2 |
| UBXN6 | UBX domain protein 6 |
| UPK3B | uroplakin 3B |
| WDR7 | WD repeat domain 7 |
| WDR91 | WD repeat domain 91 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
| ZNF669 | zinc finger protein 669 |
| ZNF675 | zinc finger protein 675 |
| ZNF701 | zinc finger protein 701 |
