Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the isometheptene-6524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD2 | abhydrolase domain containing 2 |
ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
AMPD3 | adenosine monophosphate deaminase 3 |
ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
BTF3P11 | basic transcription factor 3 pseudogene 11 |
C5ORF42 | chromosome 5 open reading frame 42 |
CA4 | carbonic anhydrase IV |
CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
CALD1 | caldesmon 1 |
CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
CHRM3 | cholinergic receptor, muscarinic 3 |
CHRND | cholinergic receptor, nicotinic, delta (muscle) |
CIB2 | calcium and integrin binding family member 2 |
CNTNAP1 | contactin associated protein 1 |
COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
CRISP2 | cysteine-rich secretory protein 2 |
CSPP1 | centrosome and spindle pole associated protein 1 |
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
DESI2 | desumoylating isopeptidase 2 |
EDA | ectodysplasin A |
EFNA3 | ephrin-A3 |
ELOVL5 | ELOVL fatty acid elongase 5 |
FGF17 | fibroblast growth factor 17 |
FHL1 | four and a half LIM domains 1 |
GALC | galactosylceramidase |
GAP43 | growth associated protein 43 |
GAS6 | growth arrest-specific 6 |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
GREM1 | gremlin 1, DAN family BMP antagonist |
GSTM5 | glutathione S-transferase mu 5 |
HDAC11 | histone deacetylase 11 |
HIPK3 | homeodomain interacting protein kinase 3 |
HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
IL16 | interleukin 16 |
INCENP | inner centromere protein antigens 135/155kDa |
INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
LAMA4 | laminin, alpha 4 |
LMF2 | lipase maturation factor 2 |
LRRN3 | leucine rich repeat neuronal 3 |
MAP2K5 | mitogen-activated protein kinase kinase 5 |
MAX | MYC associated factor X |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MSI1 | musashi RNA-binding protein 1 |
MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
NLE1 | notchless homolog 1 (Drosophila) |
NMBR | neuromedin B receptor |
NME5 | NME/NM23 family member 5 |
NRIP3 | nuclear receptor interacting protein 3 |
NRN1 | neuritin 1 |
NRP2 | neuropilin 2 |
NT5DC3 | 5'-nucleotidase domain containing 3 |
OLFM1 | olfactomedin 1 |
OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PRY | PTPN13-like, Y-linked |
PSD3 | pleckstrin and Sec7 domain containing 3 |
PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
PTPRU | protein tyrosine phosphatase, receptor type, U |
RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
RBFA | ribosome binding factor A (putative) |
RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
RPL35A | ribosomal protein L35a |
SBF1 | SET binding factor 1 |
SEC14L2 | SEC14-like 2 (S. cerevisiae) |
SIK3 | SIK family kinase 3 |
SLC17A4 | solute carrier family 17, member 4 |
SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
STX7 | syntaxin 7 |
TAL1 | T-cell acute lymphocytic leukemia 1 |
TBR1 | T-box, brain, 1 |
TLN1 | talin 1 |
TPMT | thiopurine S-methyltransferase |
VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
WIPF1 | WAS/WASL interacting protein family, member 1 |
WNT7A | wingless-type MMTV integration site family, member 7A |
WSB1 | WD repeat and SOCS box containing 1 |
XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
XYLB | xylulokinase homolog (H. influenzae) |
ZBTB48 | zinc finger and BTB domain containing 48 |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
ZMYND8 | zinc finger, MYND-type containing 8 |
ZNF277 | zinc finger protein 277 |
ZNF710 | zinc finger protein 710 |
Symbol | Name |
---|---|
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADCY7 | adenylate cyclase 7 |
AFAP1 | actin filament associated protein 1 |
APLP1 | amyloid beta (A4) precursor-like protein 1 |
ATAD5 | ATPase family, AAA domain containing 5 |
ATP11B | ATPase, class VI, type 11B |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
BCORL1 | BCL6 corepressor-like 1 |
C5AR2 | complement component 5a receptor 2 |
CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
CCDC69 | coiled-coil domain containing 69 |
CD82 | CD82 molecule |
CDH10 | cadherin 10, type 2 (T2-cadherin) |
CGA | glycoprotein hormones, alpha polypeptide |
CLCN5 | chloride channel, voltage-sensitive 5 |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CRELD1 | cysteine-rich with EGF-like domains 1 |
CRLF1 | cytokine receptor-like factor 1 |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
DDIT3 | DNA-damage-inducible transcript 3 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
EAF2 | ELL associated factor 2 |
EDAR | ectodysplasin A receptor |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FKBPL | FK506 binding protein like |
FMO4 | flavin containing monooxygenase 4 |
FOXN2 | forkhead box N2 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
GALT | galactose-1-phosphate uridylyltransferase |
GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
GPATCH3 | G patch domain containing 3 |
GPR3 | G protein-coupled receptor 3 |
GTF2I | general transcription factor IIi |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
IL17RA | interleukin 17 receptor A |
IL4R | interleukin 4 receptor |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
KIAA0754 | KIAA0754 |
KLHL25 | kelch-like family member 25 |
KLHL28 | kelch-like family member 28 |
LIME1 | Lck interacting transmembrane adaptor 1 |
LIN7B | lin-7 homolog B (C. elegans) |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
LTBP2 | latent transforming growth factor beta binding protein 2 |
LYPD1 | LY6/PLAUR domain containing 1 |
MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
MCOLN3 | mucolipin 3 |
MECR | mitochondrial trans-2-enoyl-CoA reductase |
METTL16 | methyltransferase like 16 |
MRPL2 | mitochondrial ribosomal protein L2 |
MT1HL1 | metallothionein 1H-like 1 |
MTA2 | metastasis associated 1 family, member 2 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NOL12 | nucleolar protein 12 |
NPIPB15 | nuclear pore complex interacting protein family, member B15 |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NPY5R | neuropeptide Y receptor Y5 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
PDE8B | phosphodiesterase 8B |
PDGFD | platelet derived growth factor D |
PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
PEX26 | peroxisomal biogenesis factor 26 |
PITX2 | paired-like homeodomain 2 |
RGS2 | regulator of G-protein signaling 2 |
RHBG | Rh family, B glycoprotein (gene/pseudogene) |
RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
RNF122 | ring finger protein 122 |
RPGRIP1L | RPGRIP1-like |
SAMHD1 | SAM domain and HD domain 1 |
SAV1 | salvador family WW domain containing protein 1 |
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
STK16 | serine/threonine kinase 16 |
TCHH | trichohyalin |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
TMEM120B | transmembrane protein 120B |
TMEM254 | transmembrane protein 254 |
TPST2 | tyrosylprotein sulfotransferase 2 |
TRAIP | TRAF interacting protein |
TRIM25 | tripartite motif containing 25 |
TTBK2 | tau tubulin kinase 2 |
VEZT | vezatin, adherens junctions transmembrane protein |
VPS9D1 | VPS9 domain containing 1 |
ZBTB22 | zinc finger and BTB domain containing 22 |
ZNF350 | zinc finger protein 350 |
ZNF442 | zinc finger protein 442 |
ZNF516 | zinc finger protein 516 |
ZNF750 | zinc finger protein 750 |