| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the isoniazid-1399 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ANKRD12 | ankyrin repeat domain 12 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATRN | attractin |
| BCLAF1 | BCL2-associated transcription factor 1 |
| CCPG1 | cell cycle progression 1 |
| CD101 | CD101 molecule |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTSS | cathepsin S |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EIF4E | eukaryotic translation initiation factor 4E |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GRK6 | G protein-coupled receptor kinase 6 |
| H2AFY | H2A histone family, member Y |
| HIST1H4C | histone cluster 1, H4c |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| IMPACT | impact RWD domain protein |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITM2B | integral membrane protein 2B |
| IVD | isovaleryl-CoA dehydrogenase |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) |
| KTN1 | kinectin 1 (kinesin receptor) |
| LIN7C | lin-7 homolog C (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LY75 | lymphocyte antigen 75 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MARS | methionyl-tRNA synthetase |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MED13L | mediator complex subunit 13-like |
| METTL7A | methyltransferase like 7A |
| MEX3C | mex-3 RNA binding family member C |
| MFN1 | mitofusin 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTM1 | myotubularin 1 |
| MYO1C | myosin IC |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NDRG2 | NDRG family member 2 |
| NELL2 | NEL-like 2 (chicken) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NIPBL | Nipped-B homolog (Drosophila) |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PHF2 | PHD finger protein 2 |
| PLCD1 | phospholipase C, delta 1 |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRPF4B | pre-mRNA processing factor 4B |
| PRRC2C | proline-rich coiled-coil 2C |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PTX3 | pentraxin 3, long |
| RARS | arginyl-tRNA synthetase |
| RECQL4 | RecQ protein-like 4 |
| RHOD | ras homolog family member D |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF10 | ring finger protein 10 |
| RPL38 | ribosomal protein L38 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SMC5 | structural maintenance of chromosomes 5 |
| SP3 | Sp3 transcription factor |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TBC1D5 | TBC1 domain family, member 5 |
| TMEM127 | transmembrane protein 127 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPMT | thiopurine S-methyltransferase |
| TPR | translocated promoter region, nuclear basket protein |
| TPT1 | tumor protein, translationally-controlled 1 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| VEZF1 | vascular endothelial zinc finger 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
| YIPF6 | Yip1 domain family, member 6 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF468 | zinc finger protein 468 |
| ZNF552 | zinc finger protein 552 |
| ZNF609 | zinc finger protein 609 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ACVR2A | activin A receptor, type IIA |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADRB2 | adrenoceptor beta 2, surface |
| ADTRP | androgen-dependent TFPI-regulating protein |
| APOD | apolipoprotein D |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AXIN1 | axin 1 |
| B3GNT1 | |
| BOLA1 | bolA family member 1 |
| BTNL3 | butyrophilin-like 3 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| CCDC53 | coiled-coil domain containing 53 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CDK7 | cyclin-dependent kinase 7 |
| CEP70 | centrosomal protein 70kDa |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CETN1 | centrin, EF-hand protein, 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COMMD10 | COMM domain containing 10 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRIPT | cysteine-rich PDZ-binding protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOK3 | docking protein 3 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| ECM1 | extracellular matrix protein 1 |
| ERCC8 | excision repair cross-complementation group 8 |
| FANCC | Fanconi anemia, complementation group C |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GDF9 | growth differentiation factor 9 |
| GPR27 | G protein-coupled receptor 27 |
| HIST3H2A | histone cluster 3, H2a |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| IL2RB | interleukin 2 receptor, beta |
| INO80D | INO80 complex subunit D |
| IRF7 | interferon regulatory factor 7 |
| JMJD4 | jumonji domain containing 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIFC1 | kinesin family member C1 |
| KIZ | kizuna centrosomal protein |
| LMTK1 | lemur tail kinase 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MED9 | mediator complex subunit 9 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NRBP1 | nuclear receptor binding protein 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUBP2 | nucleotide binding protein 2 |
| NXPH3 | neurexophilin 3 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| ORC3 | origin recognition complex, subunit 3 |
| OSGEP | O-sialoglycoprotein endopeptidase |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIGR | polymeric immunoglobulin receptor |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| TESK2 | testis-specific kinase 2 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| URGCP | upregulator of cell proliferation |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XDH | xanthine dehydrogenase |
| ZDHHC4 | zinc finger, DHHC-type containing 4 |
| ZNF140 | zinc finger protein 140 |
| ZNF189 | zinc finger protein 189 |
| ZNF274 | zinc finger protein 274 |
