| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the isoniazid-5840 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACACA | acetyl-CoA carboxylase alpha |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCDC40 | coiled-coil domain containing 40 |
| CCPG1 | cell cycle progression 1 |
| CD52 | CD52 molecule |
| CDH8 | cadherin 8, type 2 |
| CDHR2 | cadherin-related family member 2 |
| COL21A1 | collagen, type XXI, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTSF | cathepsin F |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DRD2 | dopamine receptor D2 |
| DSC2 | desmocollin 2 |
| DXO | decapping exoribonuclease |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM50B | family with sequence similarity 50, member B |
| FBN2 | fibrillin 2 |
| FHL1 | four and a half LIM domains 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| GAS7 | growth arrest-specific 7 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GON4L | gon-4-like (C. elegans) |
| GSTM1 | glutathione S-transferase mu 1 |
| HCG9 | HLA complex group 9 (non-protein coding) |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| IFT74 | intraflagellar transport 74 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL2 | interleukin 2 |
| ITGB8 | integrin, beta 8 |
| JUNB | jun B proto-oncogene |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF2A | kinesin heavy chain member 2A |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MGC12488 | |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NID2 | nidogen 2 (osteonidogen) |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PALMD | palmdelphin |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCNX | pecanex homolog (Drosophila) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM5 | PDZ and LIM domain 5 |
| PHF7 | PHD finger protein 7 |
| PRDM14 | PR domain containing 14 |
| PRF1 | perforin 1 (pore forming protein) |
| PROL1 | proline rich, lacrimal 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB27B | RAB27B, member RAS oncogene family |
| RAB3B | RAB3B, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RARG | retinoic acid receptor, gamma |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPS3A | ribosomal protein S3A |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SDC2 | syndecan 2 |
| SGSM2 | small G protein signaling modulator 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STX2 | syntaxin 2 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TAGLN3 | transgelin 3 |
| TAOK1 | TAO kinase 1 |
| TFIP11 | tuftelin interacting protein 11 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TRIM25 | tripartite motif containing 25 |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YY1 | YY1 transcription factor |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALS2CL | ALS2 C-terminal like |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCORL1 | BCL6 corepressor-like 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNE1 | cyclin E1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP131 | centrosomal protein 131kDa |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLEC4E | C-type lectin domain family 4, member E |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 |
| COQ6 | coenzyme Q6 monooxygenase |
| DDN | dendrin |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DENND5A | DENN/MADD domain containing 5A |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOCK1 | dedicator of cytokinesis 1 |
| DOLPP1 | dolichyldiphosphatase 1 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ECM1 | extracellular matrix protein 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM222B | family with sequence similarity 222, member B |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| FPGS | folylpolyglutamate synthase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GLCE | glucuronic acid epimerase |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HMBOX1 | homeobox containing 1 |
| HOXA1 | homeobox A1 |
| HOXA2 | homeobox A2 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| KIAA1462 | KIAA1462 |
| KRT33A | keratin 33A, type I |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAP1S | microtubule-associated protein 1S |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MMP9 | matrix metallopeptidase 9 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTMR11 | myotubularin related protein 11 |
| MTRF1 | mitochondrial translational release factor 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYO1D | myosin ID |
| MYOZ3 | myozenin 3 |
| NARFL | nuclear prelamin A recognition factor-like |
| NOL12 | nucleolar protein 12 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRSN2 | neurensin 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PLCD1 | phospholipase C, delta 1 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAI2 | retinoic acid induced 2 |
| RANGAP1 | Ran GTPase activating protein 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RPL10L | ribosomal protein L10-like |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPAG4 | sperm associated antigen 4 |
| STAC | SH3 and cysteine rich domain |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM209 | transmembrane protein 209 |
| TMEM8B | transmembrane protein 8B |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TWISTNB | TWIST neighbor |
| URM1 | ubiquitin related modifier 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XAB2 | XPA binding protein 2 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF671 | zinc finger protein 671 |
| ZNF747 | zinc finger protein 747 |
