| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the isotretinoin-6017 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APCS | amyloid P component, serum |
| ARMC4 | armadillo repeat containing 4 |
| BDKRB2 | bradykinin receptor B2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTG2 | BTG family, member 2 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAV2 | caveolin 2 |
| CCDC121 | coiled-coil domain containing 121 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CDHR2 | cadherin-related family member 2 |
| CEMP1 | cementum protein 1 |
| CLUL1 | clusterin-like 1 (retinal) |
| CSTA | cystatin A (stefin A) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDO | D-aspartate oxidase |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DOCK3 | dedicator of cytokinesis 3 |
| DRD2 | dopamine receptor D2 |
| DUSP4 | dual specificity phosphatase 4 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHB2 | EPH receptor B2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EZR | ezrin |
| FAM174B | family with sequence similarity 174, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FZD7 | frizzled class receptor 7 |
| GPR15 | G protein-coupled receptor 15 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| HAS2 | hyaluronan synthase 2 |
| HMOX1 | heme oxygenase 1 |
| HOXA5 | homeobox A5 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL33R | interleukin 33 receptor |
| ING2 | inhibitor of growth family, member 2 |
| ING4 | inhibitor of growth family, member 4 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0125 | KIAA0125 |
| KLHL20 | kelch-like family member 20 |
| KRT17 | keratin 17, type I |
| LEPR | leptin receptor |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAG | myelin associated glycoprotein |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MR1 | major histocompatibility complex, class I-related |
| MST1 | macrophage stimulating 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLA2G10 | phospholipase A2, group X |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAP1GAP | RAP1 GTPase activating protein |
| RGS16 | regulator of G-protein signaling 16 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK24 | serine/threonine kinase 24 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMOD1 | tropomodulin 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM16 | tripartite motif containing 16 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VCX2 | variable charge, X-linked 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZNF419 | zinc finger protein 419 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAG4 | BCL2-associated athanogene 4 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DUSP8 | dual specificity phosphatase 8 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAAH | fatty acid amide hydrolase |
| FAM131A | family with sequence similarity 131, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBRS | fibrosin |
| FLT4 | fms-related tyrosine kinase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GALK1 | galactokinase 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GHR | growth hormone receptor |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HECA | headcase homolog (Drosophila) |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT81 | intraflagellar transport 81 |
| IRX4 | iroquois homeobox 4 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0894 | KIAA0894 protein |
| KLHL2 | kelch-like family member 2 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MYL5 | myosin, light chain 5, regulatory |
| NAG18 | NAG18 mRNA |
| NES | nestin |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| ONECUT2 | one cut homeobox 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCDHB3 | protocadherin beta 3 |
| PGBD5 | piggyBac transposable element derived 5 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G3 | phospholipase A2, group III |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRPH | peripherin |
| PTDSS2 | phosphatidylserine synthase 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RHOB | ras homolog family member B |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SSBP3 | single stranded DNA binding protein 3 |
| STX5 | syntaxin 5 |
| SYNGR3 | synaptogyrin 3 |
| TCTN1 | tectonic family member 1 |
| ULBP2 | UL16 binding protein 2 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR4 | WD repeat domain 4 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF16 | zinc finger protein 16 |
| ZNF329 | zinc finger protein 329 |
| ZNF408 | zinc finger protein 408 |
| ZNF430 | zinc finger protein 430 |
| ZNF492 | zinc finger protein 492 |
