| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the isotretinoin-7315 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| AK1 | adenylate kinase 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| APC | adenomatous polyposis coli |
| APOC1 | apolipoprotein C-I |
| APOE | apolipoprotein E |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C1S | complement component 1, s subcomponent |
| C3 | complement component 3 |
| C7 | complement component 7 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD52 | CD52 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD82 | CD82 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 |
| CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP21A2 | cytochrome P450, family 21, subfamily A, polypeptide 2 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DCN | decorin |
| DENND3 | DENN/MADD domain containing 3 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DSPP | dentin sialophosphoprotein |
| FAM174B | family with sequence similarity 174, member B |
| FAM63B | family with sequence similarity 63, member B |
| FDX1 | ferredoxin 1 |
| FLJ11292 | |
| GAS7 | growth arrest-specific 7 |
| GOLGA2 | golgin A2 |
| GPX3 | glutathione peroxidase 3 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLHL20 | kelch-like family member 20 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MFAP3 | microfibrillar-associated protein 3 |
| MGP | matrix Gla protein |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MXD4 | MAX dimerization protein 4 |
| NOTCH3 | notch 3 |
| PALM | paralemmin |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PEG3 | paternally expressed 3 |
| PGP | phosphoglycolate phosphatase |
| PRMT2IP | PRMT2 interacting protein |
| PRSS16 | protease, serine, 16 (thymus) |
| PTGES | prostaglandin E synthase |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF122 | ring finger protein 122 |
| RPGRIP1L | RPGRIP1-like |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STAR | steroidogenic acute regulatory protein |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TMEM63A | transmembrane protein 63A |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TXLNG | taxilin gamma |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WDR25 | WD repeat domain 25 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZNF253 | zinc finger protein 253 |
| ZNF44 | zinc finger protein 44 |
| ZNF440 | zinc finger protein 440 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ACOT8 | acyl-CoA thioesterase 8 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AFAP1 | actin filament associated protein 1 |
| AKTIP | AKT interacting protein |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAG4 | BCL2-associated athanogene 4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BDNF | brain-derived neurotrophic factor |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCP110 | centriolar coiled coil protein 110kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CST4 | cystatin S |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GID4 | GID complex subunit 4 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| IL17RA | interleukin 17 receptor A |
| IL33 | interleukin 33 |
| IPP | intracisternal A particle-promoted polypeptide |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IREB2 | iron-responsive element binding protein 2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAP1S | microtubule-associated protein 1S |
| MLYCD | malonyl-CoA decarboxylase |
| MMP13 | matrix metallopeptidase 13 |
| MXRA8 | matrix-remodelling associated 8 |
| MYH15 | myosin, heavy chain 15 |
| NABP2 | nucleic acid binding protein 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PAX9 | paired box 9 |
| PDE12 | phosphodiesterase 12 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POLM | polymerase (DNA directed), mu |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB23 | RAB23, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNDC3B | RUN domain containing 3B |
| RWDD2A | RWD domain containing 2A |
| S100A3 | S100 calcium binding protein A3 |
| SCARA3 | scavenger receptor class A, member 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SSBP3 | single stranded DNA binding protein 3 |
| SSFA2 | sperm specific antigen 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SYNPO | synaptopodin |
| TAGLN3 | transgelin 3 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEP1 | telomerase-associated protein 1 |
| TH | tyrosine hydroxylase |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBG2 | tubulin, gamma 2 |
| USP18 | ubiquitin specific peptidase 18 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF267 | zinc finger protein 267 |
| ZNF273 | zinc finger protein 273 |
| ZNF350 | zinc finger protein 350 |
| ZNF358 | zinc finger protein 358 |
| ZNF701 | zinc finger protein 701 |
| ZNF711 | zinc finger protein 711 |
| ZNF767P | zinc finger family member 767, pseudogene |
