| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the isotretinoin-7438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AIM1L | absent in melanoma 1-like |
| AK2 | adenylate kinase 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALCAM | activated leukocyte cell adhesion molecule |
| BDKRB2 | bradykinin receptor B2 |
| BIN1 | bridging integrator 1 |
| BTG2 | BTG family, member 2 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA12 | carbonic anhydrase XII |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD53 | CD53 molecule |
| CEP164 | centrosomal protein 164kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLMN | calmin (calponin-like, transmembrane) |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP4 | dual specificity phosphatase 4 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPAS1 | endothelial PAS domain protein 1 |
| FAM174B | family with sequence similarity 174, member B |
| FANCA | Fanconi anemia, complementation group A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GDF11 | growth differentiation factor 11 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPX2 | glutathione peroxidase 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HHEX | hematopoietically expressed homeobox |
| HK2 | hexokinase 2 |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HOXA5 | homeobox A5 |
| HOXC13 | homeobox C13 |
| IFT140 | intraflagellar transport 140 |
| IL15RA | interleukin 15 receptor, alpha |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA0125 | KIAA0125 |
| LOC157562 | uncharacterized LOC157562 |
| MBP | myelin basic protein |
| MGC12488 | |
| MTMR2 | myotubularin related protein 2 |
| MVB12B | multivesicular body subunit 12B |
| NF2 | neurofibromin 2 (merlin) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCM1 | pericentriolar material 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G10 | phospholipase A2, group X |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLK4 | polo-like kinase 4 |
| POU4F1 | POU class 4 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGES | prostaglandin E synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PVR | poliovirus receptor |
| RAP1GAP | RAP1 GTPase activating protein |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPL35A | ribosomal protein L35a |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SH3BP2 | SH3-domain binding protein 2 |
| SIK2 | salt-inducible kinase 2 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYBU | syntabulin (syntaxin-interacting) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRIM2 | tripartite motif containing 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBG2 | tubulin, gamma 2 |
| TXNRD1 | thioredoxin reductase 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UTRN | utrophin |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ANXA1 | annexin A1 |
| ARF5 | ADP-ribosylation factor 5 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BCL9 | B-cell CLL/lymphoma 9 |
| BEX4 | brain expressed, X-linked 4 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CADM1 | cell adhesion molecule 1 |
| CAPN5 | calpain 5 |
| CBR4 | carbonyl reductase 4 |
| CCNT1 | cyclin T1 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CKB | creatine kinase, brain |
| CLSPN | claspin |
| COL9A2 | collagen, type IX, alpha 2 |
| CTSV | cathepsin V |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNM1 | dynamin 1 |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPPK1 | epiplakin 1 |
| EVPL | envoplakin |
| FAM53B | family with sequence similarity 53, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXO2 | F-box protein 2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FZD4 | frizzled class receptor 4 |
| GHR | growth hormone receptor |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH3 | G patch domain containing 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IRF7 | interferon regulatory factor 7 |
| IRX4 | iroquois homeobox 4 |
| LAMA5 | laminin, alpha 5 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRRC49 | leucine rich repeat containing 49 |
| MANBA | mannosidase, beta A, lysosomal |
| MBD5 | methyl-CpG binding domain protein 5 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN1 | mucolipin 1 |
| MICALL2 | MICAL-like 2 |
| MXD3 | MAX dimerization protein 3 |
| MXRA7 | matrix-remodelling associated 7 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXN | nucleoredoxin |
| ONECUT2 | one cut homeobox 2 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PGP | phosphoglycolate phosphatase |
| PLA2G15 | phospholipase A2, group XV |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PODXL | podocalyxin-like |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRAF2 | PRA1 domain family, member 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| SAV1 | salvador family WW domain containing protein 1 |
| SFT2D2 | SFT2 domain containing 2 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SULF1 | sulfatase 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VASH2 | vasohibin 2 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF286A | zinc finger protein 286A |
| ZNF365 | zinc finger protein 365 |
| ZNF480 | zinc finger protein 480 |
