isoxicam-1820 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the isoxicam-1820 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADCY1 adenylate cyclase 1 (brain)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
ATP10D ATPase, class V, type 10D
BAHD1 bromo adjacent homology domain containing 1
BBS9 Bardet-Biedl syndrome 9
BCL6 B-cell CLL/lymphoma 6
CASP2 caspase 2, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CCNG2 cyclin G2
CCNT2 cyclin T2
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL1A1 collagen, type I, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEAF1 DEAF1 transcription factor
DENND4A DENN/MADD domain containing 4A
DIAPH1 diaphanous-related formin 1
DSC2 desmocollin 2
DUS1L dihydrouridine synthase 1-like (S. cerevisiae)
EGR1 early growth response 1
ELOVL5 ELOVL fatty acid elongase 5
EML2 echinoderm microtubule associated protein like 2
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
FCHSD2 FCH and double SH3 domains 2
FGF1 fibroblast growth factor 1 (acidic)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H3G histone cluster 1, H3g
HN1L hematological and neurological expressed 1-like
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1L heat shock 70kDa protein 1-like
IFI16 interferon, gamma-inducible protein 16
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL1RAP interleukin 1 receptor accessory protein
INTS9 integrator complex subunit 9
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JRK Jrk homolog (mouse)
KIAA0355 KIAA0355
KLHL2 kelch-like family member 2
KLHL9 kelch-like family member 9
LARP4B La ribonucleoprotein domain family, member 4B
LOC644450 uncharacterized LOC644450
LPPR2 lipid phosphate phosphatase-related protein type 2
MAP1B microtubule-associated protein 1B
MAX MYC associated factor X
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED22 mediator complex subunit 22
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NPAS2 neuronal PAS domain protein 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PEX10 peroxisomal biogenesis factor 10
PGAP1 post-GPI attachment to proteins 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDX2 peroxiredoxin 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRB protein tyrosine phosphatase, receptor type, B
RBBP6 retinoblastoma binding protein 6
RPL10 ribosomal protein L10
RPUSD2 RNA pseudouridylate synthase domain containing 2
SAFB2 scaffold attachment factor B2
SECISBP2 SECIS binding protein 2
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPAST spastin
SRRM2 serine/arginine repetitive matrix 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SUGP1 SURP and G patch domain containing 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAOK3 TAO kinase 3
TCF3 transcription factor 3
TICAM1 toll-like receptor adaptor molecule 1
TJAP1 tight junction associated protein 1 (peripheral)
TMCO1 transmembrane and coiled-coil domains 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS2 tensin 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TUBA3C tubulin, alpha 3c
WDR62 WD repeat domain 62
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZC3H7B zinc finger CCCH-type containing 7B
ZNF133 zinc finger protein 133
ZNF358 zinc finger protein 358
ZNF444 zinc finger protein 444
ZNF675 zinc finger protein 675

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ALPK1 alpha-kinase 1
APH1B APH1B gamma secretase subunit
BBS7 Bardet-Biedl syndrome 7
BDNF brain-derived neurotrophic factor
BIN3 bridging integrator 3
C11ORF80 chromosome 11 open reading frame 80
C1ORF115 chromosome 1 open reading frame 115
CDKN2AIP CDKN2A interacting protein
CHKB choline kinase beta
CHUK conserved helix-loop-helix ubiquitous kinase
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
COG4 component of oligomeric golgi complex 4
CPEB1 cytoplasmic polyadenylation element binding protein 1
CST4 cystatin S
CTSF cathepsin F
CXORF56 chromosome X open reading frame 56
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
EIF5A2 eukaryotic translation initiation factor 5A2
FAM155A family with sequence similarity 155, member A
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FZD8 frizzled class receptor 8
GPATCH3 G patch domain containing 3
GPR1 G protein-coupled receptor 1
HDAC7 histone deacetylase 7
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HOXA4 homeobox A4
JUNB jun B proto-oncogene
KATNBL1 katanin p80 subunit B-like 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD15 potassium channel tetramerization domain containing 15
KIFC3 kinesin family member C3
KRT8P12 keratin 8 pseudogene 12
LAMC3 laminin, gamma 3
LOC730101 uncharacterized LOC730101
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MAPK12 mitogen-activated protein kinase 12
MGC12488
MNX1 motor neuron and pancreas homeobox 1
MUTYH mutY homolog
MXRA8 matrix-remodelling associated 8
NBAS neuroblastoma amplified sequence
NKRF NFKB repressing factor
NPM3 nucleophosmin/nucleoplasmin 3
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP62CL nucleoporin 62kDa C-terminal like
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
PARM1 prostate androgen-regulated mucin-like protein 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLH polymerase (DNA directed), eta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM23 RNA binding motif protein 23
RIN1 Ras and Rab interactor 1
RPS17P5 ribosomal protein S17 pseudogene 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH2D2A SH2 domain containing 2A
SHPK sedoheptulokinase
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A8 solute carrier family 12, member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMA4 glucuronidase, beta pseudogene
SOX13 SRY (sex determining region Y)-box 13
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAGLN3 transgelin 3
TH tyrosine hydroxylase
TKFC triokinase/FMN cyclase
TMC7 transmembrane channel-like 7
TMEM177 transmembrane protein 177
TMEM242 transmembrane protein 242
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSPAN12 tetraspanin 12
URM1 ubiquitin related modifier 1
USB1 U6 snRNA biogenesis 1
VASP vasodilator-stimulated phosphoprotein
VEGFB vascular endothelial growth factor B
WNT5B wingless-type MMTV integration site family, member 5B
ZC3H12A zinc finger CCCH-type containing 12A
ZNF180 zinc finger protein 180
ZNF350 zinc finger protein 350
ZNF654 zinc finger protein 654
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZNF767P zinc finger family member 767, pseudogene
ZNF85 zinc finger protein 85
ZNF862 zinc finger protein 862
ZSCAN16 zinc finger and SCAN domain containing 16