isoxicam-1862 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the isoxicam-1862 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AHI1 Abelson helper integration site 1
AKAP9 A kinase (PRKA) anchor protein 9
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAX BCL2-associated X protein
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CDC14A cell division cycle 14A
CDK13 cyclin-dependent kinase 13
CLEC4E C-type lectin domain family 4, member E
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLSPN claspin
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DDR1 discoidin domain receptor tyrosine kinase 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM102A family with sequence similarity 102, member A
FMOD fibromodulin
FRZB frizzled-related protein
FSCN3 fascin actin-bundling protein 3, testicular
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GK glycerol kinase
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HOXA1 homeobox A1
ICAM1 intercellular adhesion molecule 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
JADE3 jade family PHD finger 3
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM6B lysine (K)-specific demethylase 6B
KRIT1 KRIT1, ankyrin repeat containing
KRT8P12 keratin 8 pseudogene 12
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRC41 leucine rich repeat containing 41
LRRK1 leucine-rich repeat kinase 1
LTBP3 latent transforming growth factor beta binding protein 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MGMT O-6-methylguanine-DNA methyltransferase
MIIP migration and invasion inhibitory protein
MPZ myelin protein zero
MZF1 myeloid zinc finger 1
NCOA1 nuclear receptor coactivator 1
NF1 neurofibromin 1
NIPAL2 NIPA-like domain containing 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRP1 neuropilin 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PIDD1 p53-induced death domain protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G15 phospholipase A2, group XV
PLK4 polo-like kinase 4
PMFBP1 polyamine modulated factor 1 binding protein 1
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
QTRT1 queuine tRNA-ribosyltransferase 1
RANBP1 RAN binding protein 1
RBM5 RNA binding motif protein 5
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REST RE1-silencing transcription factor
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF25 ring finger protein 25
RNFT1 ring finger protein, transmembrane 1
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SETD2 SET domain containing 2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNX29P2 sorting nexin 29 pseudogene 2
SOX4 SRY (sex determining region Y)-box 4
SPN sialophorin
SSH3 slingshot protein phosphatase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRADD TNFRSF1A-associated via death domain
TUBGCP2 tubulin, gamma complex associated protein 2
UBAP2L ubiquitin associated protein 2-like
UBE2H ubiquitin-conjugating enzyme E2H
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZNF324 zinc finger protein 324
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD17B abhydrolase domain containing 17B
ABHD4 abhydrolase domain containing 4
ACYP2 acylphosphatase 2, muscle type
AGO4 argonaute RISC catalytic component 4
ANKRD40 ankyrin repeat domain 40
ANKRD55 ankyrin repeat domain 55
APOLD1 apolipoprotein L domain containing 1
C19ORF66 chromosome 19 open reading frame 66
C3 complement component 3
CCDC25 coiled-coil domain containing 25
CENPB centromere protein B, 80kDa
CEP97 centrosomal protein 97kDa
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FHIT fragile histidine triad
FMO4 flavin containing monooxygenase 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP2 ganglioside induced differentiation associated protein 2
GIPC1 GIPC PDZ domain containing family, member 1
GPKOW G patch domain and KOW motifs
GPR65 G protein-coupled receptor 65
HIST1H2BI histone cluster 1, H2bi
HIST1H2BJ histone cluster 1, H2bj
HIST1H4J histone cluster 1, H4j
HP haptoglobin
IFI44L interferon-induced protein 44-like
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL24 interleukin 24
IMPAD1 inositol monophosphatase domain containing 1
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITPKC inositol-trisphosphate 3-kinase C
KATNBL1 katanin p80 subunit B-like 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0319L KIAA0319-like
KIAA0586 KIAA0586
KIF13B kinesin family member 13B
KIF18A kinesin family member 18A
LAX1 lymphocyte transmembrane adaptor 1
LXN latexin
LY6E lymphocyte antigen 6 complex, locus E
MCOLN1 mucolipin 1
MDM4 MDM4, p53 regulator
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKL2 MKL/myocardin-like 2
MOB3B MOB kinase activator 3B
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYBBP1A MYB binding protein (P160) 1a
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
MYO9A myosin IXA
NKG7 natural killer cell granule protein 7
NOL6 nucleolar protein 6 (RNA-associated)
NSD1 nuclear receptor binding SET domain protein 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARPBP PARP1 binding protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PEMT phosphatidylethanolamine N-methyltransferase
PIEZO1 piezo-type mechanosensitive ion channel component 1
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POMZP3 POM121 and ZP3 fusion
PRR3 proline rich 3
PRR7 proline rich 7 (synaptic)
PRRC1 proline-rich coiled-coil 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RARS arginyl-tRNA synthetase
RETN resistin
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF167 ring finger protein 167
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S1PR4 sphingosine-1-phosphate receptor 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHPK sedoheptulokinase
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLITRK5 SLIT and NTRK-like family, member 5
STAP1 signal transducing adaptor family member 1
TAOK1 TAO kinase 1
TEC tec protein tyrosine kinase
TMEM53 transmembrane protein 53
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
USP19 ubiquitin specific peptidase 19
XAB2 XPA binding protein 2
ZBTB6 zinc finger and BTB domain containing 6
ZNF175 zinc finger protein 175