| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the isoxsuprine-4789 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMACR | alpha-methylacyl-CoA racemase |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APOC1 | apolipoprotein C-I |
| APOE | apolipoprotein E |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| B9D1 | B9 protein domain 1 |
| BCL2A1 | BCL2-related protein A1 |
| BEST2 | bestrophin 2 |
| BTNL3 | butyrophilin-like 3 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD47 | CD47 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEL | carboxyl ester lipase |
| CFP | complement factor properdin |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLTC | clathrin, heavy chain (Hc) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COMMD4 | COMM domain containing 4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA3 | ephrin-A3 |
| EPN1 | epsin 1 |
| ESR1 | estrogen receptor 1 |
| FGF13 | fibroblast growth factor 13 |
| FLOT1 | flotillin 1 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPC1 | glypican 1 |
| GPR182 | G protein-coupled receptor 182 |
| HIC2 | hypermethylated in cancer 2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL22 | interleukin 22 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLHL20 | kelch-like family member 20 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT24 | keratin 24, type I |
| KRT9 | keratin 9, type I |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYT1 | myelin transcription factor 1 |
| NEK1 | NIMA-related kinase 1 |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| NRSN2 | neurensin 2 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALM | paralemmin |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLXNA2 | plexin A2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PVRL3 | poliovirus receptor-related 3 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RAD51 | RAD51 recombinase |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| S100A8 | S100 calcium binding protein A8 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIRT5 | sirtuin 5 |
| SIX1 | SIX homeobox 1 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPON2 | spondin 2, extracellular matrix protein |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBKBP1 | TBK1 binding protein 1 |
| TBL1X | transducin (beta)-like 1X-linked |
| TPP1 | tripeptidyl peptidase I |
| TRIM66 | tripartite motif containing 66 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UPK3B | uroplakin 3B |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF701 | zinc finger protein 701 |
| Symbol | Name |
|---|---|
| ACVR2A | activin A receptor, type IIA |
| AKTIP | AKT interacting protein |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX4 | chromobox homolog 4 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC9 | coiled-coil domain containing 9 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDKN2AIP | CDKN2A interacting protein |
| CFD | complement factor D (adipsin) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COMMD10 | COMM domain containing 10 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DEAF1 | DEAF1 transcription factor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYSF | dysferlin |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM186A | family with sequence similarity 186, member A |
| FAM188A | family with sequence similarity 188, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO22 | F-box protein 22 |
| FOXA1 | forkhead box A1 |
| FUZ | fuzzy planar cell polarity protein |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GOLGA8B | golgin A8 family, member B |
| HIST1H2BC | histone cluster 1, H2bc |
| HMOX1 | heme oxygenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IFT54 | intraflagellar transport 54 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF13A | kinesin family member 13A |
| KIFAP3 | kinesin-associated protein 3 |
| KRT31 | keratin 31, type I |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MICALL2 | MICAL-like 2 |
| MITF | microphthalmia-associated transcription factor |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLD3 | phospholipase D family, member 3 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QPCT | glutaminyl-peptide cyclotransferase |
| RGS2 | regulator of G-protein signaling 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMIM14 | small integral membrane protein 14 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TGDS | TDP-glucose 4,6-dehydratase |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM115 | transmembrane protein 115 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| VWA9 | von Willebrand factor A domain containing 9 |
| WDR4 | WD repeat domain 4 |
| WDR76 | WD repeat domain 76 |
| YIPF5 | Yip1 domain family, member 5 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF571 | zinc finger protein 571 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |
| ZNF778 | zinc finger protein 778 |
| ZNF816 | zinc finger protein 816 |
