isradipine-3129 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the isradipine-3129 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADAM28 ADAM metallopeptidase domain 28
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDOB aldolase B, fructose-bisphosphate
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOM apolipoprotein M
BCL2L1 BCL2-like 1
BMP7 bone morphogenetic protein 7
BTN2A2 butyrophilin, subfamily 2, member A2
C11ORF16 chromosome 11 open reading frame 16
C19ORF73 chromosome 19 open reading frame 73
C1ORF61 chromosome 1 open reading frame 61
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMKV CaM kinase-like vesicle-associated
CCDC33 coiled-coil domain containing 33
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL7A1 collagen, type VII, alpha 1
DCAF15 DDB1 and CUL4 associated factor 15
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK3 docking protein 3
ENDOD1 endonuclease domain containing 1
ESR1 estrogen receptor 1
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM120C family with sequence similarity 120C
FLJ11710 uncharacterized protein FLJ11710
FN1 fibronectin 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAS6 growth arrest-specific 6
GP2 glycoprotein 2 (zymogen granule membrane)
GPATCH4 G patch domain containing 4
GRB7 growth factor receptor-bound protein 7
HES1 hes family bHLH transcription factor 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMG20B high mobility group 20B
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
IFT27 intraflagellar transport 27
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL1A interleukin 1, alpha
IL7R interleukin 7 receptor
INO80B INO80 complex subunit B
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IZUMO4 IZUMO family member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0319L KIAA0319-like
KSR1 kinase suppressor of ras 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAP1A microtubule-associated protein 1A
MAP4 microtubule-associated protein 4
MBP myelin basic protein
MT1M metallothionein 1M
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTL5 metallothionein-like 5, testis-specific (tesmin)
NTNG1 netrin G1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PBX2 pre-B-cell leukemia homeobox 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RBPMS RNA binding protein with multiple splicing
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RECQL5 RecQ protein-like 5
RGS14 regulator of G-protein signaling 14
RIBC2 RIB43A domain with coiled-coils 2
RIMS3 regulating synaptic membrane exocytosis 3
RNASE4 ribonuclease, RNase A family, 4
RXRB retinoid X receptor, beta
SCAND2P SCAN domain containing 2 pseudogene
SH2D4A SH2 domain containing 4A
SOX13 SRY (sex determining region Y)-box 13
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRR serine racemase
TBX2 T-box 2
TESK1 testis-specific kinase 1
THBS1 thrombospondin 1
TLDC1 TBC/LysM-associated domain containing 1
TMEM51 transmembrane protein 51
TNK1 tyrosine kinase, non-receptor, 1
TNP2 transition protein 2 (during histone to protamine replacement)
TPMT thiopurine S-methyltransferase
UTS2 urotensin 2
YLPM1 YLP motif containing 1
YPEL1 yippee-like 1 (Drosophila)
ZIC3 Zic family member 3
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ALG3 ALG3, alpha-1,3- mannosyltransferase
ARL15 ADP-ribosylation factor-like 15
ATAD5 ATPase family, AAA domain containing 5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C12ORF43 chromosome 12 open reading frame 43
C1ORF216 chromosome 1 open reading frame 216
C1RL complement component 1, r subcomponent-like
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN15 calpain 15
CD180 CD180 molecule
CLTCL1 clathrin, heavy chain-like 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYSLTR1 cysteinyl leukotriene receptor 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPDC5 DEP domain containing 5
EGR2 early growth response 2
ENAH enabled homolog (Drosophila)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXN2 forkhead box N2
GAMT guanidinoacetate N-methyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GSTA4 glutathione S-transferase alpha 4
GSTM2 glutathione S-transferase mu 2 (muscle)
HCAR3 hydroxycarboxylic acid receptor 3
HDAC9 histone deacetylase 9
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
KIF13B kinesin family member 13B
KLF13 Kruppel-like factor 13
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LATS1 large tumor suppressor kinase 1
LINC00115 long intergenic non-protein coding RNA 115
MBIP MAP3K12 binding inhibitory protein 1
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
METTL2B methyltransferase like 2B
MKRN3 makorin ring finger protein 3
MOGS mannosyl-oligosaccharide glucosidase
MRPL44 mitochondrial ribosomal protein L44
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYBPH myosin binding protein H
MYO1E myosin IE
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NDE1 nudE neurodevelopment protein 1
NFE2L3 nuclear factor, erythroid 2-like 3
NKRF NFKB repressing factor
NLK nemo-like kinase
NMB neuromedin B
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAQR4 progestin and adipoQ receptor family member IV
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PITX2 paired-like homeodomain 2
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PNMA1 paraneoplastic Ma antigen 1
PRR3 proline rich 3
PWAR5 Prader Willi/Angelman region RNA 5
RHOBTB2 Rho-related BTB domain containing 2
RPA4 replication protein A4, 30kDa
SALL2 spalt-like transcription factor 2
SCD5 stearoyl-CoA desaturase 5
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMR3A submaxillary gland androgen regulated protein 3A
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAR steroidogenic acute regulatory protein
TERT telomerase reverse transcriptase
THBS4 thrombospondin 4
TMEM159 transmembrane protein 159
TMEM53 transmembrane protein 53
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TWSG1 twisted gastrulation BMP signaling modulator 1
VSIG10 V-set and immunoglobulin domain containing 10
VSIG4 V-set and immunoglobulin domain containing 4
VWA9 von Willebrand factor A domain containing 9
ZBTB10 zinc finger and BTB domain containing 10
ZBTB6 zinc finger and BTB domain containing 6
ZNF426 zinc finger protein 426
ZNF480 zinc finger protein 480
ZNF787 zinc finger protein 787
ZSCAN31 zinc finger and SCAN domain containing 31