| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the isradipine-5447 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADRA1A | adrenoceptor alpha 1A |
| ALOX5 | arachidonate 5-lipoxygenase |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| B9D1 | B9 protein domain 1 |
| BIN1 | bridging integrator 1 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCDC57 | coiled-coil domain containing 57 |
| CCKBR | cholecystokinin B receptor |
| CLEC4A | C-type lectin domain family 4, member A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DICER1 | dicer 1, ribonuclease type III |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNM3 | dynamin 3 |
| DRD1 | dopamine receptor D1 |
| EDA | ectodysplasin A |
| FOXG1 | forkhead box G1 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR15 | G protein-coupled receptor 15 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTA1 | glutathione S-transferase alpha 1 |
| HOXD1 | homeobox D1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL1B | interleukin 1, beta |
| IL2 | interleukin 2 |
| IL4R | interleukin 4 receptor |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| JMJD6 | jumonji domain containing 6 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIF13B | kinesin family member 13B |
| KRT31 | keratin 31, type I |
| KRT83 | keratin 83, type II |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIMK1 | LIM domain kinase 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRP1B | low density lipoprotein receptor-related protein 1B |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAP4 | microtubule-associated protein 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MEF2D | myocyte enhancer factor 2D |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MGC2889 | uncharacterized protein MGC2889 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYO15A | myosin XVA |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCLN | nicalin |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NOTCH3 | notch 3 |
| NOX1 | NADPH oxidase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OLAH | oleoyl-ACP hydrolase |
| PASK | PAS domain containing serine/threonine kinase |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PMEL | premelanosome protein |
| POU2F3 | POU class 2 homeobox 3 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS12 | regulator of G-protein signaling 12 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOCS3 | suppressor of cytokine signaling 3 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TAOK2 | TAO kinase 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMPRSS2 | transmembrane protease, serine 2 |
| TSPAN32 | tetraspanin 32 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TUBA3C | tubulin, alpha 3c |
| UPK3B | uroplakin 3B |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| WSCD1 | WSC domain containing 1 |
| ZNF215 | zinc finger protein 215 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ATP10D | ATPase, class V, type 10D |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BFSP1 | beaded filament structural protein 1, filensin |
| CEP97 | centrosomal protein 97kDa |
| CFD | complement factor D (adipsin) |
| CTAGE9 | CTAGE family, member 9 |
| CTSF | cathepsin F |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DMTN | dematin actin binding protein |
| DSCAM | Down syndrome cell adhesion molecule |
| EMID1 | EMI domain containing 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM169A | family with sequence similarity 169, member A |
| FAM212B | family with sequence similarity 212, member B |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GMPR | guanosine monophosphate reductase |
| GPR143 | G protein-coupled receptor 143 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H4A | histone cluster 1, H4a |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0754 | KIAA0754 |
| KLC2 | kinesin light chain 2 |
| KLF2 | Kruppel-like factor 2 |
| KLHL28 | kelch-like family member 28 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LAMA3 | laminin, alpha 3 |
| LHX6 | LIM homeobox 6 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEFV | Mediterranean fever |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTCL1 | microtubule crosslinking factor 1 |
| N4BP3 | NEDD4 binding protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOL10 | nucleolar protein 10 |
| NOL12 | nucleolar protein 12 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PC | pyruvate carboxylase |
| PCDHA9 | protocadherin alpha 9 |
| PCDHB3 | protocadherin beta 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS22 | protease, serine, 22 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RGS2 | regulator of G-protein signaling 2 |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SKI | SKI proto-oncogene |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STRA6 | stimulated by retinoic acid 6 |
| TAZ | tafazzin |
| TEP1 | telomerase-associated protein 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TH | tyrosine hydroxylase |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM2 | transmembrane protein 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM5 | tripartite motif containing 5 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBG2 | tubulin, gamma 2 |
| VGF | VGF nerve growth factor inducible |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YEATS2 | YEATS domain containing 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF408 | zinc finger protein 408 |
| ZNF573 | zinc finger protein 573 |
| ZNF747 | zinc finger protein 747 |
