itga2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)|This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 3673)
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Genes

20 genes co-occuring with the biological term itga2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CDKN2A cyclin-dependent kinase inhibitor 2A
CREBBP CREB binding protein
GATA3 GATA binding protein 3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
IL5RA interleukin 5 receptor, alpha
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LPL lipoprotein lipase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PELO pelota homolog (Drosophila)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
TGM4 transglutaminase 4