itk Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	IL2-inducible T-cell kinase\|This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3702)
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Genes

16 genes co-occuring with the biological term itk in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
BTK	Bruton agammaglobulinemia tyrosine kinase
CXCL12	chemokine (C-X-C motif) ligand 12
CXCR4	chemokine (C-X-C motif) receptor 4
DEF6	differentially expressed in FDCP 6 homolog (mouse)
FOXP3	forkhead box P3
GNA13	guanine nucleotide binding protein (G protein), alpha 13
ITK	IL2-inducible T-cell kinase
LAT	linker for activation of T cells
LCK	LCK proto-oncogene, Src family tyrosine kinase
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SH2D2A	SH2 domain containing 2A
SRF	serum response factor (c-fos serum response element-binding transcription factor)
TEC	tec protein tyrosine kinase
TXK	TXK tyrosine kinase
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa