| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the ivermectin-2213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADRA1B | adrenoceptor alpha 1B |
| AREG | amphiregulin |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BAIAP3 | BAI1-associated protein 3 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CD70 | CD70 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFB | complement factor B |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLIC2 | chloride intracellular channel 2 |
| COL1A1 | collagen, type I, alpha 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DRD1 | dopamine receptor D1 |
| EFNB3 | ephrin-B3 |
| EPHB6 | EPH receptor B6 |
| FCAR | Fc fragment of IgA receptor |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GMPR | guanosine monophosphate reductase |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4H | histone cluster 1, H4h |
| HOXC5 | homeobox C5 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IL2RG | interleukin 2 receptor, gamma |
| INHBE | inhibin, beta E |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LAMC2 | laminin, gamma 2 |
| LIF | leukemia inhibitory factor |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC157562 | uncharacterized LOC157562 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAOA | monoamine oxidase A |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MEF2D | myocyte enhancer factor 2D |
| MRC2 | mannose receptor, C type 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYT1 | myelin transcription factor 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NF2 | neurofibromin 2 (merlin) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NNAT | neuronatin |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OPRK1 | opioid receptor, kappa 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PSPH | phosphoserine phosphatase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RND1 | Rho family GTPase 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SERHL2 | serine hydrolase-like 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| THRB | thyroid hormone receptor, beta |
| TLR2 | toll-like receptor 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNF | tumor necrosis factor |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TPP1 | tripeptidyl peptidase I |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TXNIP | thioredoxin interacting protein |
| UPK1B | uroplakin 1B |
| VEGFA | vascular endothelial growth factor A |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD3 | abhydrolase domain containing 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADCY7 | adenylate cyclase 7 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARSB | arylsulfatase B |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP13A2 | ATPase type 13A2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C5AR2 | complement component 5a receptor 2 |
| CA2 | carbonic anhydrase II |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBX8 | chromobox homolog 8 |
| CDK18 | cyclin-dependent kinase 18 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CORO7 | coronin 7 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXI1 | forkhead box I1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GATA4 | GATA binding protein 4 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BF | histone cluster 1, H2bf |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFT140 | intraflagellar transport 140 |
| IL17RA | interleukin 17 receptor A |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KLHL25 | kelch-like family member 25 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL8 | methyltransferase like 8 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NEK11 | NIMA-related kinase 11 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARD6A | par-6 family cell polarity regulator alpha |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMP22 | peripheral myelin protein 22 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR4 | proline rich 4 (lacrimal) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB30 | RAB30, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RNF2 | ring finger protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SYNC | syncoilin, intermediate filament protein |
| TDRD1 | tudor domain containing 1 |
| TMEM164 | transmembrane protein 164 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| XK | X-linked Kx blood group |
| ZIC3 | Zic family member 3 |
| ZNF611 | zinc finger protein 611 |
| ZNF675 | zinc finger protein 675 |
