| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the ivermectin-5853 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALX4 | ALX homeobox 4 |
| APOC4 | apolipoprotein C-IV |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDC14B | cell division cycle 14B |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CTSF | cathepsin F |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDO | D-aspartate oxidase |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DST | dystonin |
| DTNA | dystrobrevin, alpha |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPHB2 | EPH receptor B2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FBXO40 | F-box protein 40 |
| GAN | gigaxonin |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GSTA3 | glutathione S-transferase alpha 3 |
| HDAC5 | histone deacetylase 5 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGHM | immunoglobulin heavy constant mu |
| IL11 | interleukin 11 |
| INADL | InaD-like (Drosophila) |
| KYNU | kynureninase |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAK | male germ cell-associated kinase |
| MANBA | mannosidase, beta A, lysosomal |
| METTL7A | methyltransferase like 7A |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MXD4 | MAX dimerization protein 4 |
| MYRF | myelin regulatory factor |
| NDRG1 | N-myc downstream regulated 1 |
| NF2 | neurofibromin 2 (merlin) |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NOTCH2 | notch 2 |
| NOTCH4 | notch 4 |
| NOX1 | NADPH oxidase 1 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OSMR | oncostatin M receptor |
| PASK | PAS domain containing serine/threonine kinase |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE10A | phosphodiesterase 10A |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHF1 | PHD finger protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRAMEF11 | PRAME family member 11 |
| PROSER1 | proline and serine rich 1 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAB29 | RAB29, member RAS oncogene family |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RASA2 | RAS p21 protein activator 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPL10 | ribosomal protein L10 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STAC | SH3 and cysteine rich domain |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SYMPK | symplekin |
| SYNJ2 | synaptojanin 2 |
| TAZ | tafazzin |
| TENM1 | teneurin transmembrane protein 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| UTRN | utrophin |
| WEE1 | WEE1 G2 checkpoint kinase |
| WIZ | widely interspaced zinc finger motifs |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF227 | zinc finger protein 227 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| AXIN1 | axin 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C5 | complement component 5 |
| CAPN15 | calpain 15 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDCA3 | cell division cycle associated 3 |
| CDON | cell adhesion associated, oncogene regulated |
| CENPT | centromere protein T |
| CEP85 | centrosomal protein 85kDa |
| CNTNAP3B | contactin associated protein-like 3B |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTSK | cathepsin K |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EVPL | envoplakin |
| FANCE | Fanconi anemia, complementation group E |
| FOXK2 | forkhead box K2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH3 | G patch domain containing 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HAMP | hepcidin antimicrobial peptide |
| HIRA | histone cell cycle regulator |
| HIST1H3G | histone cluster 1, H3g |
| HLX | H2.0-like homeobox |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFNA14 | interferon, alpha 14 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| KIAA1549L | KIAA1549-like |
| KLHL3 | kelch-like family member 3 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRRC6 | leucine rich repeat containing 6 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| NAG18 | NAG18 mRNA |
| NARFL | nuclear prelamin A recognition factor-like |
| NID2 | nidogen 2 (osteonidogen) |
| NUBP2 | nucleotide binding protein 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PALMD | palmdelphin |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PKN1 | protein kinase N1 |
| PLAC8 | placenta-specific 8 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLM | polymerase (DNA directed), mu |
| PRPH | peripherin |
| PRSS22 | protease, serine, 22 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RANBP17 | RAN binding protein 17 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RNF121 | ring finger protein 121 |
| RPL10L | ribosomal protein L10-like |
| SCRN3 | secernin 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHPK | sedoheptulokinase |
| SHROOM2 | shroom family member 2 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SMYD3 | SET and MYND domain containing 3 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPEG | SPEG complex locus |
| SRBD1 | S1 RNA binding domain 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TLN1 | talin 1 |
| TMEM184C | transmembrane protein 184C |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP18 | ubiquitin specific peptidase 18 |
| USP6NL | USP6 N-terminal like |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF276 | zinc finger protein 276 |
| ZNF551 | zinc finger protein 551 |
| ZNF592 | zinc finger protein 592 |
| ZNF671 | zinc finger protein 671 |
| ZNF816 | zinc finger protein 816 |
