| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the ivermectin-7206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACE | angiotensin I converting enzyme |
| ALOX12 | arachidonate 12-lipoxygenase |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP9A | ATPase, class II, type 9A |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C1RL | complement component 1, r subcomponent-like |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DIO2 | deiodinase, iodothyronine, type II |
| DLC1 | DLC1 Rho GTPase activating protein |
| DPYS | dihydropyrimidinase |
| EGR3 | early growth response 3 |
| EMID1 | EMI domain containing 1 |
| ETV7 | ets variant 7 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FHL2 | four and a half LIM domains 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTPBP2 | GTP binding protein 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXC8 | homeobox C8 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL24 | interleukin 24 |
| INHBE | inhibin, beta E |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDM4C | lysine (K)-specific demethylase 4C |
| KRT6B | keratin 6B, type II |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIF | leukemia inhibitory factor |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPFF | neuropeptide FF-amide peptide precursor |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUP188 | nucleoporin 188kDa |
| NUP54 | nucleoporin 54kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OCM2 | oncomodulin 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PODNL1 | podocan-like 1 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF170 | ring finger protein 170 |
| RPL7 | ribosomal protein L7 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMC1A | structural maintenance of chromosomes 1A |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNPO | synaptopodin |
| TAT | tyrosine aminotransferase |
| TDRD3 | tudor domain containing 3 |
| THBS1 | thrombospondin 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TLR2 | toll-like receptor 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARSB | arylsulfatase B |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BMP4 | bone morphogenetic protein 4 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CAPN15 | calpain 15 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHMP7 | charged multivesicular body protein 7 |
| CIT | citron rho-interacting serine/threonine kinase |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRBN | cereblon |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTSK | cathepsin K |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DENND4A | DENN/MADD domain containing 4A |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| EDC4 | enhancer of mRNA decapping 4 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EVPL | envoplakin |
| FAAH | fatty acid amide hydrolase |
| FAM111A | family with sequence similarity 111, member A |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM189B | family with sequence similarity 189, member B |
| GHR | growth hormone receptor |
| GLTP | glycolipid transfer protein |
| GPATCH1 | G patch domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC13 | homeobox C13 |
| HSPA2 | heat shock 70kDa protein 2 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| ITPKC | inositol-trisphosphate 3-kinase C |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRRC42 | leucine rich repeat containing 42 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED20 | mediator complex subunit 20 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MISP | mitotic spindle positioning |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MON1B | MON1 secretory trafficking family member B |
| MSX1 | msh homeobox 1 |
| MXD3 | MAX dimerization protein 3 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G10 | phospholipase A2, group X |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLH | polymerase (DNA directed), eta |
| PP14571 | uncharacterized LOC100130449 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RASA2 | RAS p21 protein activator 2 |
| RECQL4 | RecQ protein-like 4 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| S100A4 | S100 calcium binding protein A4 |
| SCAI | suppressor of cancer cell invasion |
| SDF2 | stromal cell-derived factor 2 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SNHG3 | small nucleolar RNA host gene 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TESK2 | testis-specific kinase 2 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM62 | transmembrane protein 62 |
| TMSB15A | thymosin beta 15a |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| UNKL | unkempt family zinc finger-like |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF205 | zinc finger protein 205 |
| ZNF668 | zinc finger protein 668 |
