jak2 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Janus kinase 2|This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3717)
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Genes

66 proteins co-occuring with the biological term jak2 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACP1 acid phosphatase 1, soluble
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATF2 activating transcription factor 2
BAD BCL2-associated agonist of cell death
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR2 chemokine (C-C motif) receptor 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCR4 chemokine (C-X-C motif) receptor 4
ELK1 ELK1, member of ETS oncogene family
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ETV6 ets variant 6
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
GAB2 GRB2-associated binding protein 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GHR growth hormone receptor
GTF2I general transcription factor IIi
HIST1H3A histone cluster 1, H3a
HLTF helicase-like transcription factor
IFNGR1 interferon gamma receptor 1
INSR insulin receptor
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
LEPR leptin receptor
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
OSBP oxysterol binding protein
OSMR oncostatin M receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRLR prolactin receptor
PRMT5 protein arginine methyltransferase 5
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RHOA ras homolog family member A
RPS6 ribosomal protein S6
SH2B1 SH2B adaptor protein 1
SIRPA signal-regulatory protein alpha
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SOCS3 suppressor of cytokine signaling 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAP2 signal transducing adaptor family member 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced