| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the josamycin-1950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ARSJ | arylsulfatase family, member J |
| BIN1 | bridging integrator 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CALCR | calcitonin receptor |
| CD53 | CD53 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLIC5 | chloride intracellular channel 5 |
| CLTA | clathrin, light chain A |
| COPS7B | COP9 signalosome subunit 7B |
| CRY2 | cryptochrome circadian clock 2 |
| CSN2 | casein beta |
| CTH | cystathionine gamma-lyase |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DAZAP2 | DAZ associated protein 2 |
| DENND2A | DENN/MADD domain containing 2A |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DRD2 | dopamine receptor D2 |
| FBLN1 | fibulin 1 |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FGA | fibrinogen alpha chain |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GRK5 | G protein-coupled receptor kinase 5 |
| GUK1 | guanylate kinase 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HMOX2 | heme oxygenase 2 |
| HOXD9 | homeobox D9 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL16 | interleukin 16 |
| INO80D | INO80 complex subunit D |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| KLF6 | Kruppel-like factor 6 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LOC81691 | exonuclease NEF-sp |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MECP2 | methyl CpG binding protein 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP27 | matrix metallopeptidase 27 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MYO1C | myosin IC |
| MYO9B | myosin IXB |
| NELL2 | NEL-like 2 (chicken) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NKX3-1 | NK3 homeobox 1 |
| NPTXR | neuronal pentraxin receptor |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUP205 | nucleoporin 205kDa |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RANBP10 | RAN binding protein 10 |
| RHAG | Rh-associated glycoprotein |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RNASEH2B | ribonuclease H2, subunit B |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SAFB | scaffold attachment factor B |
| SALL2 | spalt-like transcription factor 2 |
| SH2D1A | SH2 domain containing 1A |
| SH2D2A | SH2 domain containing 2A |
| SIRT6 | sirtuin 6 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SLN | sarcolipin |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TDRKH | tudor and KH domain containing |
| TEAD3 | TEA domain family member 3 |
| TMEM97 | transmembrane protein 97 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRAF3IP2 | TRAF3 interacting protein 2 |
| TTR | transthyretin |
| USP24 | ubiquitin specific peptidase 24 |
| ZNF117 | zinc finger protein 117 |
| ZNF669 | zinc finger protein 669 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CCNA1 | cyclin A1 |
| CEP85 | centrosomal protein 85kDa |
| COBL | cordon-bleu WH2 repeat protein |
| CPTP | ceramide-1-phosphate transfer protein |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTSF | cathepsin F |
| CYTH2 | cytohesin 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNM1 | dynamin 1 |
| EPS8L2 | EPS8-like 2 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAM188A | family with sequence similarity 188, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| GALR3 | galanin receptor 3 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMPPB | GDP-mannose pyrophosphorylase B |
| HEBP1 | heme binding protein 1 |
| HIRIP3 | HIRA interacting protein 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF9 | interferon regulatory factor 9 |
| JAM3 | junctional adhesion molecule 3 |
| JRKL | JRK-like |
| JUP | junction plakoglobin |
| KLHL26 | kelch-like family member 26 |
| KRT34 | keratin 34, type I |
| LETMD1 | LETM1 domain containing 1 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP1S | microtubule-associated protein 1S |
| MAP6D1 | MAP6 domain containing 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICALL2 | MICAL-like 2 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MRPS15 | mitochondrial ribosomal protein S15 |
| MRPS27 | mitochondrial ribosomal protein S27 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NUP93 | nucleoporin 93kDa |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK1IP1 | PAK1 interacting protein 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYGB | phosphorylase, glycogen; brain |
| RBBP5 | retinoblastoma binding protein 5 |
| RIC8A | RIC8 guanine nucleotide exchange factor A |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS21 | ribosomal protein S21 |
| SAP30L | SAP30-like |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35E3 | solute carrier family 35, member E3 |
| SNX17 | sorting nexin 17 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STRN4 | striatin, calmodulin binding protein 4 |
| STX10 | syntaxin 10 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCTN2 | tectonic family member 2 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THAP11 | THAP domain containing 11 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM104 | transmembrane protein 104 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRIM8 | tripartite motif containing 8 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| WDR13 | WD repeat domain 13 |
| WRN | Werner syndrome, RecQ helicase-like |
| WWC2 | WW and C2 domain containing 2 |
| ZFP36 | ZFP36 ring finger protein |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF14 | zinc finger protein 14 |
| ZNF358 | zinc finger protein 358 |
| ZNF532 | zinc finger protein 532 |