josamycin-1950 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the josamycin-1950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALPPL2 alkaline phosphatase, placental-like 2
ARSJ arylsulfatase family, member J
BIN1 bridging integrator 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C19ORF57 chromosome 19 open reading frame 57
C1ORF159 chromosome 1 open reading frame 159
CALCR calcitonin receptor
CD53 CD53 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHD3 chromodomain helicase DNA binding protein 3
CHRM4 cholinergic receptor, muscarinic 4
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CIZ1 CDKN1A interacting zinc finger protein 1
CLIC5 chloride intracellular channel 5
CLTA clathrin, light chain A
COPS7B COP9 signalosome subunit 7B
CRY2 cryptochrome circadian clock 2
CSN2 casein beta
CTH cystathionine gamma-lyase
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAZAP2 DAZ associated protein 2
DENND2A DENN/MADD domain containing 2A
DLK2 delta-like 2 homolog (Drosophila)
DRD2 dopamine receptor D2
FBLN1 fibulin 1
FBXW4 F-box and WD repeat domain containing 4
FGA fibrinogen alpha chain
FGFR1 fibroblast growth factor receptor 1
FUBP1 far upstream element (FUSE) binding protein 1
GHRHR growth hormone releasing hormone receptor
GP2 glycoprotein 2 (zymogen granule membrane)
GRK5 G protein-coupled receptor kinase 5
GUK1 guanylate kinase 1
H2AFY2 H2A histone family, member Y2
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HMOX2 heme oxygenase 2
HOXD9 homeobox D9
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL16 interleukin 16
INO80D INO80 complex subunit D
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
KLF6 Kruppel-like factor 6
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC81691 exonuclease NEF-sp
MAP2K5 mitogen-activated protein kinase kinase 5
MECP2 methyl CpG binding protein 2
MFSD11 major facilitator superfamily domain containing 11
MMP27 matrix metallopeptidase 27
MTERF4 mitochondrial transcription termination factor 4
MUC2 mucin 2, oligomeric mucus/gel-forming
MYO1C myosin IC
MYO9B myosin IXB
NELL2 NEL-like 2 (chicken)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKX3-1 NK3 homeobox 1
NPTXR neuronal pentraxin receptor
NSD1 nuclear receptor binding SET domain protein 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP205 nucleoporin 205kDa
NXT2 nuclear transport factor 2-like export factor 2
PBX1 pre-B-cell leukemia homeobox 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRKG2 protein kinase, cGMP-dependent, type II
PTGDS prostaglandin D2 synthase 21kDa (brain)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RANBP10 RAN binding protein 10
RHAG Rh-associated glycoprotein
RIPK2 receptor-interacting serine-threonine kinase 2
RNASEH2B ribonuclease H2, subunit B
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAFB scaffold attachment factor B
SALL2 spalt-like transcription factor 2
SH2D1A SH2 domain containing 1A
SH2D2A SH2 domain containing 2A
SIRT6 sirtuin 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SLN sarcolipin
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TDRKH tudor and KH domain containing
TEAD3 TEA domain family member 3
TMEM97 transmembrane protein 97
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP2 TRAF3 interacting protein 2
TTR transthyretin
USP24 ubiquitin specific peptidase 24
ZNF117 zinc finger protein 117
ZNF669 zinc finger protein 669

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
APLP1 amyloid beta (A4) precursor-like protein 1
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C12ORF43 chromosome 12 open reading frame 43
C2CD5 C2 calcium-dependent domain containing 5
CCNA1 cyclin A1
CEP85 centrosomal protein 85kDa
COBL cordon-bleu WH2 repeat protein
CPTP ceramide-1-phosphate transfer protein
CTDNEP1 CTD nuclear envelope phosphatase 1
CTSF cathepsin F
CYTH2 cytohesin 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNM1 dynamin 1
EPS8L2 EPS8-like 2
ERMP1 endoplasmic reticulum metallopeptidase 1
FAM188A family with sequence similarity 188, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGD6 FYVE, RhoGEF and PH domain containing 6
GALR3 galanin receptor 3
GBAP1 glucosidase, beta, acid pseudogene 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPPB GDP-mannose pyrophosphorylase B
HEBP1 heme binding protein 1
HIRIP3 HIRA interacting protein 3
HMGB3P1 high mobility group box 3 pseudogene 1
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
JAM3 junctional adhesion molecule 3
JRKL JRK-like
JUP junction plakoglobin
KLHL26 kelch-like family member 26
KRT34 keratin 34, type I
LETMD1 LETM1 domain containing 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MAGOHB mago-nashi homolog B (Drosophila)
MAP1S microtubule-associated protein 1S
MAP6D1 MAP6 domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MICALL2 MICAL-like 2
MPV17 MpV17 mitochondrial inner membrane protein
MRPS15 mitochondrial ribosomal protein S15
MRPS27 mitochondrial ribosomal protein S27
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NHEJ1 nonhomologous end-joining factor 1
NPDC1 neural proliferation, differentiation and control, 1
NUP93 nucleoporin 93kDa
PAAF1 proteasomal ATPase-associated factor 1
PADI1 peptidyl arginine deiminase, type I
PAK1IP1 PAK1 interacting protein 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PKD2 polycystic kidney disease 2 (autosomal dominant)
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYGB phosphorylase, glycogen; brain
RBBP5 retinoblastoma binding protein 5
RIC8A RIC8 guanine nucleotide exchange factor A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPP25 ribonuclease P/MRP 25kDa subunit
RPS21 ribosomal protein S21
SAP30L SAP30-like
SERTAD3 SERTA domain containing 3
SETD8 SET domain containing (lysine methyltransferase) 8
SH3GL1 SH3-domain GRB2-like 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35E3 solute carrier family 35, member E3
SNX17 sorting nexin 17
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRN4 striatin, calmodulin binding protein 4
STX10 syntaxin 10
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCTN2 tectonic family member 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THAP11 THAP domain containing 11
TIMP2 TIMP metallopeptidase inhibitor 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM104 transmembrane protein 104
TNNT1 troponin T type 1 (skeletal, slow)
TRIM8 tripartite motif containing 8
TWSG1 twisted gastrulation BMP signaling modulator 1
UBIAD1 UbiA prenyltransferase domain containing 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
WDR13 WD repeat domain 13
WRN Werner syndrome, RecQ helicase-like
WWC2 WW and C2 domain containing 2
ZFP36 ZFP36 ring finger protein
ZIM2 zinc finger, imprinted 2
ZNF14 zinc finger protein 14
ZNF358 zinc finger protein 358
ZNF532 zinc finger protein 532