| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the josamycin-2034 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| API5 | apoptosis inhibitor 5 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| BAIAP2 | BAI1-associated protein 2 |
| BAX | BCL2-associated X protein |
| BCL7A | B-cell CLL/lymphoma 7A |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C6ORF106 | chromosome 6 open reading frame 106 |
| CALCR | calcitonin receptor |
| CD24 | CD24 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDHR2 | cadherin-related family member 2 |
| CDV3 | CDV3 homolog (mouse) |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COG5 | component of oligomeric golgi complex 5 |
| COL4A2 | collagen, type IV, alpha 2 |
| COPA | coatomer protein complex, subunit alpha |
| CREM | cAMP responsive element modulator |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYB561 | cytochrome b561 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| ELMO2 | engulfment and cell motility 2 |
| ENG | endoglin |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| ERLIN1 | ER lipid raft associated 1 |
| FAM13A | family with sequence similarity 13, member A |
| FAM162A | family with sequence similarity 162, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLE1 | GLE1 RNA export mediator |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HBB | hemoglobin, beta |
| HIRA | histone cell cycle regulator |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIFC1 | kinesin family member C1 |
| KLF12 | Kruppel-like factor 12 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MAGEB2 | melanoma antigen family B2 |
| MCC | mutated in colorectal cancers |
| MCL1 | myeloid cell leukemia 1 |
| METAP2 | methionyl aminopeptidase 2 |
| MLH3 | mutL homolog 3 |
| MOB3B | MOB kinase activator 3B |
| MPZL1 | myelin protein zero-like 1 |
| MSH3 | mutS homolog 3 |
| MYO9B | myosin IXB |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NELL2 | NEL-like 2 (chicken) |
| NMT2 | N-myristoyltransferase 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 |
| NUP214 | nucleoporin 214kDa |
| OCRL | oculocerebrorenal syndrome of Lowe |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCM1 | pericentriolar material 1 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PQLC2 | PQ loop repeat containing 2 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RPL10 | ribosomal protein L10 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC38A7 | solute carrier family 38, member 7 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TM6SF2 | transmembrane 6 superfamily member 2 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| Symbol | Name |
|---|---|
| AHCTF1 | AT hook containing transcription factor 1 |
| ALPK1 | alpha-kinase 1 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKRD46 | ankyrin repeat domain 46 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATXN2 | ataxin 2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCORL1 | BCL6 corepressor-like 1 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CHKA | choline kinase alpha |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSD | cathepsin D |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM1 | dynamin 1 |
| DPYD | dihydropyrimidine dehydrogenase |
| DYM | dymeclin |
| ECT2 | epithelial cell transforming 2 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FAM192A | family with sequence similarity 192, member A |
| FAM53B | family with sequence similarity 53, member B |
| FANCF | Fanconi anemia, complementation group F |
| FBXO5 | F-box protein 5 |
| FMNL1 | formin-like 1 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPATCH1 | G patch domain containing 1 |
| H1FX | H1 histone family, member X |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') |
| HOMER1 | homer scaffolding protein 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0753 | KIAA0753 |
| KIF18A | kinesin family member 18A |
| KIFAP3 | kinesin-associated protein 3 |
| KIN | Kin17 DNA and RNA binding protein |
| KLHL21 | kelch-like family member 21 |
| LOC100272216 | uncharacterized LOC100272216 |
| LOC642236 | FSHD region gene 1 pseudogene |
| MAP1S | microtubule-associated protein 1S |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MMP2 | matrix metallopeptidase 2 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NPPA | natriuretic peptide A |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RECQL4 | RecQ protein-like 4 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| SFXN1 | sideroflexin 1 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SKI | SKI proto-oncogene |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD7 | SMAD family member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNX15 | sorting nexin 15 |
| SPIN1 | spindlin 1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STRN4 | striatin, calmodulin binding protein 4 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 |
| SYNGR2 | synaptogyrin 2 |
| TBL3 | transducin (beta)-like 3 |
| TCTN2 | tectonic family member 2 |
| TMEM127 | transmembrane protein 127 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRIB1 | tribbles pseudokinase 1 |
| TSPAN32 | tetraspanin 32 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TWIST1 | twist family bHLH transcription factor 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| UNKL | unkempt family zinc finger-like |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF175 | zinc finger protein 175 |
| ZNF189 | zinc finger protein 189 |
| ZNF33B | zinc finger protein 33B |
| ZNF443 | zinc finger protein 443 |
| ZNF529 | zinc finger protein 529 |
| ZNF669 | zinc finger protein 669 |
| ZNF804A | zinc finger protein 804A |