| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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192 genes differentially expressed following the josamycin-4631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ANKRD6 | ankyrin repeat domain 6 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ARTN | artemin |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG10 | autophagy related 10 |
| BNC1 | basonuclin 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C2CD2L | C2CD2-like |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CDC14A | cell division cycle 14A |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLDN11 | claudin 11 |
| COL3A1 | collagen, type III, alpha 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DRP2 | dystrophin related protein 2 |
| DTNA | dystrobrevin, alpha |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ETV1 | ets variant 1 |
| EXO5 | exonuclease 5 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FAM63A | family with sequence similarity 63, member A |
| FGF18 | fibroblast growth factor 18 |
| FMO3 | flavin containing monooxygenase 3 |
| FRK | fyn-related Src family tyrosine kinase |
| FUZ | fuzzy planar cell polarity protein |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR27 | G protein-coupled receptor 27 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
| GRK4 | G protein-coupled receptor kinase 4 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NFRKB | nuclear factor related to kappaB binding protein |
| NOL10 | nucleolar protein 10 |
| NRAP | nebulin-related anchoring protein |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUP210 | nucleoporin 210kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PACRG | PARK2 co-regulated |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRO2964 | uncharacterized protein PRO2964 |
| RBM12B | RNA binding motif protein 12B |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RIN3 | Ras and Rab interactor 3 |
| RNF122 | ring finger protein 122 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SETD1A | SET domain containing 1A |
| SFTPC | surfactant protein C |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SP100 | SP100 nuclear antigen |
| SRRT | serrate, RNA effector molecule |
| STC1 | stanniocalcin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TRIM29 | tripartite motif containing 29 |
| TRIM48 | tripartite motif containing 48 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN9 | tetraspanin 9 |
| UST | uronyl-2-sulfotransferase |
| WDR62 | WD repeat domain 62 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACOXL | acyl-CoA oxidase-like |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1S | complement component 1, s subcomponent |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASS4 | Cas scaffolding protein family member 4 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHMP6 | charged multivesicular body protein 6 |
| CISH | cytokine inducible SH2-containing protein |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CSF1R | colony stimulating factor 1 receptor |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DUOX2 | dual oxidase 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGF6 | fibroblast growth factor 6 |
| FILIP1L | filamin A interacting protein 1-like |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GAS8 | growth arrest-specific 8 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2AL | histone cluster 1, H2al |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA7 | homeobox A7 |
| ICOS | inducible T-cell co-stimulator |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0319L | KIAA0319-like |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC157562 | uncharacterized LOC157562 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCPH1 | microcephalin 1 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTSS1L | metastasis suppressor 1-like |
| MYO1F | myosin IF |
| NEUROD1 | neuronal differentiation 1 |
| NNAT | neuronatin |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NTF3 | neurotrophin 3 |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARPBP | PARP1 binding protein |
| PDE8B | phosphodiesterase 8B |
| PDZK1 | PDZ domain containing 1 |
| PER3 | period circadian clock 3 |
| PLVAP | plasmalemma vesicle associated protein |
| PRM2 | protamine 2 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGR | retinal G protein coupled receptor |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPEG | SPEG complex locus |
| SSBP3 | single stranded DNA binding protein 3 |
| STAB2 | stabilin 2 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| WDR91 | WD repeat domain 91 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF208 | zinc finger protein 208 |
| ZNF442 | zinc finger protein 442 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF84 | zinc finger protein 84 |