josamycin-5692 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the josamycin-5692 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AIRE autoimmune regulator
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
ANGPTL2 angiopoietin-like 2
AQP3 aquaporin 3 (Gill blood group)
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BLZF1 basic leucine zipper nuclear factor 1
C2CD2L C2CD2-like
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CADM3 cell adhesion molecule 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CC2D1A coiled-coil and C2 domain containing 1A
CCL8 chemokine (C-C motif) ligand 8
CD58 CD58 molecule
CD80 CD80 molecule
CDK13 cyclin-dependent kinase 13
CNTN5 contactin 5
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CUL7 cullin 7
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCTN2 dynactin 2 (p50)
DNASE1L2 deoxyribonuclease I-like 2
DTX2 deltex 2, E3 ubiquitin ligase
EDRF1 erythroid differentiation regulatory factor 1
ELOVL2 ELOVL fatty acid elongase 2
ELSPBP1 epididymal sperm binding protein 1
EMC3 ER membrane protein complex subunit 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EXTL1 exostosin-like glycosyltransferase 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK3P glycerol kinase 3 pseudogene
GLRA1 glycine receptor, alpha 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HIPK2 homeodomain interacting protein kinase 2
HRASLS2 HRAS-like suppressor 2
IGHA1 immunoglobulin heavy constant alpha 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBC inhibin, beta C
KDM8 lysine (K)-specific demethylase 8
KRT37 keratin 37, type I
LGALS9 lectin, galactoside-binding, soluble, 9
LINC01587 long intergenic non-protein coding RNA 1587
LOC647070 uncharacterized LOC647070
LPIN1 lipin 1
LRP12 low density lipoprotein receptor-related protein 12
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBD3 methyl-CpG binding domain protein 3
MDFI MyoD family inhibitor
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MR1 major histocompatibility complex, class I-related
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OSGIN1 oxidative stress induced growth inhibitor 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRAMEF12 PRAME family member 12
PRKCA protein kinase C, alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
RAP2B RAP2B, member of RAS oncogene family
RBMXL2 RNA binding motif protein, X-linked-like 2
RFPL2 ret finger protein-like 2
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SLIT2 slit homolog 2 (Drosophila)
SMYD2 SET and MYND domain containing 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPON1 spondin 1, extracellular matrix protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX7 synovial sarcoma, X breakpoint 7
SYNE1 spectrin repeat containing, nuclear envelope 1
TBX5 T-box 5
TDRKH tudor and KH domain containing
THY1 Thy-1 cell surface antigen
TJAP1 tight junction associated protein 1 (peripheral)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM242 transmembrane protein 242
TMOD2 tropomodulin 2 (neuronal)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM3 tripartite motif containing 3
TSSK2 testis-specific serine kinase 2
TXNRD3 thioredoxin reductase 3
VIPR1 vasoactive intestinal peptide receptor 1
ZNF407 zinc finger protein 407
ZNF484 zinc finger protein 484
ZNF76 zinc finger protein 76
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACTL8 actin-like 8
AGMAT agmatine ureohydrolase (agmatinase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP15 bone morphogenetic protein 15
BTD biotinidase
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CASS4 Cas scaffolding protein family member 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC121 coiled-coil domain containing 121
CD70 CD70 molecule
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCF1 cardiotrophin-like cytokine factor 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRIP1 cysteine-rich protein 1 (intestinal)
CUEDC1 CUE domain containing 1
DOCK1 dedicator of cytokinesis 1
ELP6 elongator acetyltransferase complex subunit 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC6B exocyst complex component 6B
FAM186A family with sequence similarity 186, member A
FAM198B family with sequence similarity 198, member B
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GMIP GEM interacting protein
GSTA4 glutathione S-transferase alpha 4
HIST1H2AK histone cluster 1, H2ak
HOXA4 homeobox A4
HOXD11 homeobox D11
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP1 inositol polyphosphate-1-phosphatase
IQCG IQ motif containing G
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
LARP6 La ribonucleoprotein domain family, member 6
LPXN leupaxin
LTBP2 latent transforming growth factor beta binding protein 2
LYPLA2P1 lysophospholipase II pseudogene 1
MATK megakaryocyte-associated tyrosine kinase
MMP2 matrix metallopeptidase 2
MXD3 MAX dimerization protein 3
NES nestin
NFE2L3 nuclear factor, erythroid 2-like 3
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCA2 oculocutaneous albinism II
ODF2 outer dense fiber of sperm tails 2
OTUD3 OTU deubiquitinase 3
PAQR6 progestin and adipoQ receptor family member VI
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGR progesterone receptor
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
RUSC2 RUN and SH3 domain containing 2
SHARPIN SHANK-associated RH domain interactor
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SND1-IT1 SND1 intronic transcript 1
STIM1 stromal interaction molecule 1
TBR1 T-box, brain, 1
TCTN2 tectonic family member 2
TDRD12 tudor domain containing 12
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPST2 tyrosylprotein sulfotransferase 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBXN6 UBX domain protein 6
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR25 WD repeat domain 25
WDR33 WD repeat domain 33
ZBTB39 zinc finger and BTB domain containing 39
ZFP69B ZFP69 zinc finger protein B
ZNF350 zinc finger protein 350
ZNF750 zinc finger protein 750
ZNF862 zinc finger protein 862