junctional zone Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The murine placenta consists of two main fetally derived compartments: the labyrinthine zone and the junctional zone. (BRENDA Tissue and Enzyme Source Ontology, BTO_0005401)
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Genes

263 proteins co-occuring with the tissue junctional zone in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ASCL2 achaete-scute family bHLH transcription factor 2 2.31075
PCDH12 protocadherin 12 1.5765
GJA1 gap junction protein, alpha 1, 43kDa 1.57209
JAM3 junctional adhesion molecule 3 1.55406
GJB3 gap junction protein, beta 3, 31kDa 1.4888
ESRRB estrogen-related receptor beta 1.37179
GCM1 glial cells missing homolog 1 (Drosophila) 1.33184
JAM2 junctional adhesion molecule 2 1.30658
TJP1 tight junction protein 1 1.20334
GJB5 gap junction protein, beta 5, 31.1kDa 1.17136
PRL prolactin 1.11376
F11R F11 receptor 1.10491
ESX1 ESX homeobox 1 1.07883
GJA5 gap junction protein, alpha 5, 40kDa 1.07221
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 1.05853
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.05017
CSH2 chorionic somatomammotropin hormone 2 1.03171
WDFY1 WD repeat and FYVE domain containing 1 1.02513
TFEB transcription factor EB 0.998908
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.942215
OCLN occludin 0.925907
FGF4 fibroblast growth factor 4 0.918633
CDX2 caudal type homeobox 2 0.885862
EOMES eomesodermin 0.885438
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.870217
IGHJ6 immunoglobulin heavy joining 6 0.859679
PLET1 placenta expressed transcript 1 0.854629
PLAC1 placenta-specific 1 0.846644
TJP2 tight junction protein 2 0.839091
HAND1 heart and neural crest derivatives expressed 1 0.825686
CGN cingulin 0.825268
IRF6 interferon regulatory factor 6 0.816068
JUP junction plakoglobin 0.808134
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.786468
JPH3 junctophilin 3 0.783972
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.778155
GJB2 gap junction protein, beta 2, 26kDa 0.77193
FLT1 fms-related tyrosine kinase 1 0.77027
HLA-E major histocompatibility complex, class I, E 0.765296
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.75247
IGF2 insulin-like growth factor 2 0.749579
CASQ2 calsequestrin 2 (cardiac muscle) 0.749166
TMEM43 transmembrane protein 43 0.743801
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.740915
HK3 hexokinase 3 (white cell) 0.73803
LAMB3 laminin, beta 3 0.734735
GJC1 gap junction protein, gamma 1, 45kDa 0.733912
STOX1 storkhead box 1 0.716651
GJB1 gap junction protein, beta 1, 32kDa 0.71501
IGSF5 immunoglobulin superfamily, member 5 0.7105
TLE2 transducin-like enhancer of split 2 0.705993
FBXW8 F-box and WD repeat domain containing 8 0.705583
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.702308
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.697399
LAMC2 laminin, gamma 2 0.694946
SLMAP sarcolemma associated protein 0.690042
CDH5 cadherin 5, type 2 (vascular endothelium) 0.664775
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.658272
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.656648
SLC38A2 solute carrier family 38, member 2 0.622639
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.621024
SYMPK symplekin 0.615377
CUL7 cullin 7 0.612152
PEG10 paternally expressed 10 0.610943
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.608527
PREP prolyl endopeptidase 0.606514
PSG9 pregnancy specific beta-1-glycoprotein 9 0.597263
SOCS3 suppressor of cytokine signaling 3 0.592444
MSTO1 misato 1, mitochondrial distribution and morphology regulator 0.589234
MIP major intrinsic protein of lens fiber 0.588431
FMO1 flavin containing monooxygenase 1 0.585224
UNK unkempt family zinc finger 0.572418
CNTN5 contactin 5 0.571219
PITPNB phosphatidylinositol transfer protein, beta 0.568424
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.564833
NCOA6 nuclear receptor coactivator 6 0.558856
BIRC6 baculoviral IAP repeat containing 6 0.551695
CLDN1 claudin 1 0.550901
PARD6A par-6 family cell polarity regulator alpha 0.550106
TLE3 transducin-like enhancer of split 3 0.546136
CLDN7 claudin 7 0.544152
PLIN4 perilipin 4 0.537416
CLDN4 claudin 4 0.536229
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.533065
NID1 nidogen 1 0.531089
CLDN10 claudin 10 0.509027
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.508242
SOX13 SRY (sex determining region Y)-box 13 0.507849
AKR1C1 aldo-keto reductase family 1, member C1 0.503141
MPDZ multiple PDZ domain protein 0.502357
GJC3 gap junction protein, gamma 3, 30.2kDa 0.500398
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.492963
CDX4 caudal type homeobox 4 0.476589
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 0.475812
RAB13 RAB13, member RAS oncogene family 0.4634
COL17A1 collagen, type XVII, alpha 1 0.451428
DGKZ diacylglycerol kinase, zeta 0.450271
RBM15 RNA binding motif protein 15 0.449886
USP18 ubiquitin specific peptidase 18 0.449501
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.435289
MCM7 minichromosome maintenance complex component 7 0.433757
GYS1 glycogen synthase 1 (muscle) 0.431077
INHBB inhibin, beta B 0.430695
ERVW-1 endogenous retrovirus group W, member 1 0.425344
STK3 serine/threonine kinase 3 0.421148
IGFBP1 insulin-like growth factor binding protein 1 0.412771
DGKA diacylglycerol kinase, alpha 80kDa 0.411631
DPP6 dipeptidyl-peptidase 6 0.408592
DNTT DNA nucleotidylexotransferase 0.400628
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.3976
MTNR1A melatonin receptor 1A 0.397222
CPD carboxypeptidase D 0.397222
LGALS13 lectin, galactoside-binding, soluble, 13 0.394953
EMILIN1 elastin microfibril interfacer 1 0.394576
HES3 hes family bHLH transcription factor 3 0.393819
YBX3 Y box binding protein 3 0.387404
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.377621
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.375368
PKP2 plakophilin 2 0.372743
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.37087
STK26 serine/threonine protein kinase 26 0.367129
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.366381
HLA-G major histocompatibility complex, class I, G 0.36302
ACP1 acid phosphatase 1, soluble 0.361527
MARVELD2 MARVEL domain containing 2 0.360782
ELF5 E74-like factor 5 (ets domain transcription factor) 0.360409
COL5A1 collagen, type V, alpha 1 0.354455
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.350372
HMX2 H6 family homeobox 2 0.348519
PYGB phosphorylase, glycogen; brain 0.341863
PYGL phosphorylase, glycogen, liver 0.340757
FST follistatin 0.33965
PTPRB protein tyrosine phosphatase, receptor type, B 0.33965
NOTCH2NL notch 2 N-terminal like 0.33965
NOTCH2 notch 2 0.337072
PYGM phosphorylase, glycogen, muscle 0.335968
RYR1 ryanodine receptor 1 (skeletal) 0.333396
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.332661
IGLV7-43 immunoglobulin lambda variable 7-43 0.325701
INHBA inhibin, beta A 0.324605
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.324239
ENO2 enolase 2 (gamma, neuronal) 0.323874
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.319863
FOSL1 FOS-like antigen 1 0.31877
BCL6 B-cell CLL/lymphoma 6 0.316951
TRDN triadin 0.312232
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.311145
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.307889
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.306805
IGF2R insulin-like growth factor 2 receptor 0.306805
ECM1 extracellular matrix protein 1 0.306083
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.305722
DNAH8 dynein, axonemal, heavy chain 8 0.305722
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.302118
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.301758
CA2 carbonic anhydrase II 0.30032
PALLD palladin, cytoskeletal associated protein 0.297447
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.297089
HOPX HOP homeobox 0.294939
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.289582
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.282483
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.280717
GRB10 growth factor receptor-bound protein 10 0.278955
LSR lipolysis stimulated lipoprotein receptor 0.276495
CD1A CD1a molecule 0.276495
RAPSN receptor-associated protein of the synapse 0.275094
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.272997
FBLN1 fibulin 1 0.268482
POU1F1 POU class 1 homeobox 1 0.266757
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.265725
EGLN3 egl-9 family hypoxia-inducible factor 3 0.257907
COL4A1 collagen, type IV, alpha 1 0.257572
SPHK2 sphingosine kinase 2 0.256568
DSG2 desmoglein 2 0.2559
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.255567
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.254902
CDC73 cell division cycle 73 0.251279
ADRA2B adrenoceptor alpha 2B 0.250953
PDHX pyruvate dehydrogenase complex, component X 0.249653
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.241746
TARP TCR gamma alternate reading frame protein 0.240826
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.240216
SCN1A sodium channel, voltage gated, type I alpha subunit 0.237216
PRDM1 PR domain containing 1, with ZNF domain 0.233162
TIMP3 TIMP metallopeptidase inhibitor 3 0.232599
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.23011
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.229568
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.228234
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.226155
TYR tyrosinase 0.2259
KRT17 keratin 17, type I 0.225395
VIM vimentin 0.224645
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.224398
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.224398
IGFBP6 insulin-like growth factor binding protein 6 0.221833
TRIM21 tripartite motif containing 21 0.221291
AHR aryl hydrocarbon receptor 0.221061
ITGAV integrin, alpha V 0.220303
TIMP2 TIMP metallopeptidase inhibitor 2 0.217974
UGP2 UDP-glucose pyrophosphorylase 2 0.216933
AMHR2 anti-Mullerian hormone receptor, type II 0.21573
TNC tenascin C 0.212761
S100A6 S100 calcium binding protein A6 0.194695
TNS1 tensin 1 0.194161
CPE carboxypeptidase E 0.192674
XDH xanthine dehydrogenase 0.191694
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.191648
H3F3B H3 histone, family 3B (H3.3B) 0.191509
H3F3A H3 histone, family 3A 0.191509
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.190696
KDR kinase insert domain receptor 0.190658
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.190297
IGFBP3 insulin-like growth factor binding protein 3 0.190258
PGF placental growth factor 0.190232
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.190099
PCSK6 proprotein convertase subtilisin/kexin type 6 0.189801
JUNB jun B proto-oncogene 0.189746
FGF5 fibroblast growth factor 5 0.189732
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.189705
PRLH prolactin releasing hormone 0.189663
ACVRL1 activin A receptor type II-like 1 0.189195
KLF5 Kruppel-like factor 5 (intestinal) 0.189151
IL16 interleukin 16 0.188931
CDX1 caudal type homeobox 1 0.188856
ESRRA estrogen-related receptor alpha 0.188841
CUL1 cullin 1 0.188584
VEGFA vascular endothelial growth factor A 0.188476
WDR20 WD repeat domain 20 0.18832
ISG15 ISG15 ubiquitin-like modifier 0.188099
TBX3 T-box 3 0.18797
HGFAC HGF activator 0.18784
ARNT aryl hydrocarbon receptor nuclear translocator 0.187741
PCSK7 proprotein convertase subtilisin/kexin type 7 0.187658
PTEN phosphatase and tensin homolog 0.187575
GADD45B growth arrest and DNA-damage-inducible, beta 0.187558
FEN1 flap structure-specific endonuclease 1 0.187303
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.186776
GPR162 G protein-coupled receptor 162 0.18643
UBE3A ubiquitin protein ligase E3A 0.186393
NUMB numb homolog (Drosophila) 0.186318
FOXO1 forkhead box O1 0.186262
AHCY adenosylhomocysteinase 0.185802
LIFR leukemia inhibitory factor receptor alpha 0.185465
MCAM melanoma cell adhesion molecule 0.185323
POU5F1B POU class 5 homeobox 1B 0.185323
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.184781
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.184369
CD24 CD24 molecule 0.184011
SOD3 superoxide dismutase 3, extracellular 0.183618
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.183548
GSK3B glycogen synthase kinase 3 beta 0.183018
EGFR epidermal growth factor receptor 0.18282
FGF1 fibroblast growth factor 1 (acidic) 0.1821
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.181994
PLIN2 perilipin 2 0.181967
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.181697
GFER growth factor, augmenter of liver regeneration 0.181616
UMOD uromodulin 0.18114
DCN decorin 0.180852
POU5F1 POU class 5 homeobox 1 0.180706
CDC25A cell division cycle 25A 0.180527
HLA-B major histocompatibility complex, class I, B 0.180195
GLB1 galactosidase, beta 1 0.179823