kaempferol-3579 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the kaempferol-3579 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C1 aldo-keto reductase family 1, member C1
AMACR alpha-methylacyl-CoA racemase
AMT aminomethyltransferase
ANGPT1 angiopoietin 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
AREG amphiregulin
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B9D2 B9 protein domain 2
BDKRB2 bradykinin receptor B2
BMP10 bone morphogenetic protein 10
C2 complement component 2
C8ORF44 chromosome 8 open reading frame 44
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCPG1 cell cycle progression 1
CD1A CD1a molecule
CD58 CD58 molecule
CD6 CD6 molecule
CEP295 centrosomal protein 295kDa
CTSF cathepsin F
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DRD2 dopamine receptor D2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EGR1 early growth response 1
EGR3 early growth response 3
EML3 echinoderm microtubule associated protein like 3
ETV5 ets variant 5
FOXI1 forkhead box I1
FOXN3 forkhead box N3
GTPBP1 GTP binding protein 1
HIP1 huntingtin interacting protein 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOMER3 homer scaffolding protein 3
HOXA10 homeobox A10
IDUA iduronidase, alpha-L-
INHBE inhibin, beta E
IPO5 importin 5
IRF4 interferon regulatory factor 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0125 KIAA0125
KLHL22 kelch-like family member 22
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK11 mitogen-activated protein kinase 11
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOF myoferlin
NAV2 neuron navigator 2
NEUROD1 neuronal differentiation 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PALM paralemmin
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM7 PDZ and LIM domain 7 (enigma)
PITX1 paired-like homeodomain 1
PLAC4 placenta-specific 4
PTHLH parathyroid hormone-like hormone
PURA purine-rich element binding protein A
RECQL5 RecQ protein-like 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RELN reelin
RFTN1 raftlin, lipid raft linker 1
RNF19B ring finger protein 19B
RPH3A rabphilin 3A
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAFB scaffold attachment factor B
SBNO1 strawberry notch homolog 1 (Drosophila)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SMAD3 SMAD family member 3
SPARCL1 SPARC-like 1 (hevin)
SPRY4 sprouty homolog 4 (Drosophila)
STK11 serine/threonine kinase 11
SYNJ2 synaptojanin 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAS Wiskott-Aldrich syndrome
WDR59 WD repeat domain 59
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABI3BP ABI family, member 3 (NESH) binding protein
ADAP2 ArfGAP with dual PH domains 2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB1 arrestin, beta 1
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF73 chromosome 19 open reading frame 73
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CDK3 cyclin-dependent kinase 3
CFAP45 cilia and flagella associated protein 45
CLDN9 claudin 9
CLIC3 chloride intracellular channel 3
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOC2A double C2-like domains, alpha
EFNA1 ephrin-A1
ENO2 enolase 2 (gamma, neuronal)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM186A family with sequence similarity 186, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FLJ11710 uncharacterized protein FLJ11710
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLRA1 glycine receptor, alpha 1
GPR157 G protein-coupled receptor 157
GPR176 G protein-coupled receptor 176
H1F0 H1 histone family, member 0
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1D histone cluster 1, H1d
HIST1H3B histone cluster 1, H3b
HIST1H4C histone cluster 1, H4c
HIST1H4F histone cluster 1, H4f
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KLF2 Kruppel-like factor 2
KRT8P12 keratin 8 pseudogene 12
LRRC49 leucine rich repeat containing 49
LYPD1 LY6/PLAUR domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MMP2 matrix metallopeptidase 2
NDE1 nudE neurodevelopment protein 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NLGN1 neuroligin 1
OSMR oncostatin M receptor
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGA10 protocadherin gamma subfamily A, 10
PDE12 phosphodiesterase 12
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PNPLA6 patatin-like phospholipase domain containing 6
PP14571 uncharacterized LOC100130449
PRB3 proline-rich protein BstNI subfamily 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTDSS2 phosphatidylserine synthase 2
RFPL1S RFPL1 antisense RNA 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
RUNDC3B RUN domain containing 3B
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SERGEF secretion regulating guanine nucleotide exchange factor
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMR3A submaxillary gland androgen regulated protein 3A
ST5 suppression of tumorigenicity 5
SULT4A1 sulfotransferase family 4A, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TLR5 toll-like receptor 5
TMEM209 transmembrane protein 209
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TUBA3C tubulin, alpha 3c
URM1 ubiquitin related modifier 1
VAV3 vav 3 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR76 WD repeat domain 76
ZBTB44 zinc finger and BTB domain containing 44
ZFHX2 zinc finger homeobox 2
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324