kaempferol-5839 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the kaempferol-5839 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHI1 Abelson helper integration site 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
AMT aminomethyltransferase
APOLD1 apolipoprotein L domain containing 1
ARHGAP33 Rho GTPase activating protein 33
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BMP2K BMP2 inducible kinase
C9ORF9 chromosome 9 open reading frame 9
CA5B carbonic anhydrase VB, mitochondrial
CCDC93 coiled-coil domain containing 93
CD82 CD82 molecule
CDH8 cadherin 8, type 2
CEP164 centrosomal protein 164kDa
CLN5 ceroid-lipofuscinosis, neuronal 5
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CROCC ciliary rootlet coiled-coil, rootletin
CSRNP3 cysteine-serine-rich nuclear protein 3
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTC1 CTS telomere maintenance complex component 1
DEAF1 DEAF1 transcription factor
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DRD2 dopamine receptor D2
ELSPBP1 epididymal sperm binding protein 1
EMC3 ER membrane protein complex subunit 3
ERAP1 endoplasmic reticulum aminopeptidase 1
EREG epiregulin
FAM50B family with sequence similarity 50, member B
FCF1 FCF1 rRNA-processing protein
FGF2 fibroblast growth factor 2 (basic)
GALC galactosylceramidase
GLUL glutamate-ammonia ligase
GTPBP4 GTP binding protein 4
HIST1H3C histone cluster 1, H3c
HOXA4 homeobox A4
HOXC10 homeobox C10
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF4 interferon regulatory factor 4
JAK2 Janus kinase 2
KIF1A kinesin family member 1A
KRT75 keratin 75, type II
KRT86 keratin 86, type II
LOC647070 uncharacterized LOC647070
LRRC6 leucine rich repeat containing 6
MANBA mannosidase, beta A, lysosomal
MAP2K7 mitogen-activated protein kinase kinase 7
MARS methionyl-tRNA synthetase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED28 mediator complex subunit 28
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
N4BP2L2 NEDD4 binding protein 2-like 2
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NRTN neurturin
PANK3 pantothenate kinase 3
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PRB3 proline-rich protein BstNI subfamily 3
QKI QKI, KH domain containing, RNA binding
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOT2 ras homolog family member T2
RNASE4 ribonuclease, RNase A family, 4
SGK2 serum/glucocorticoid regulated kinase 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC25A44 solute carrier family 25, member 44
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD4 SMAD family member 4
SOX13 SRY (sex determining region Y)-box 13
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRN3 striatin, calmodulin binding protein 3
TBX10 T-box 10
TCP10 t-complex 10
TEX40 testis expressed 40
TMEM209 transmembrane protein 209
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOP3A topoisomerase (DNA) III alpha
TPST2 tyrosylprotein sulfotransferase 2
TRIM2 tripartite motif containing 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSKU tsukushi, small leucine rich proteoglycan
TTC22 tetratricopeptide repeat domain 22
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VCAN versican
YY1 YY1 transcription factor
ZBTB40 zinc finger and BTB domain containing 40
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF614 zinc finger protein 614
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ALPK1 alpha-kinase 1
ARL14 ADP-ribosylation factor-like 14
ASB8 ankyrin repeat and SOCS box containing 8
ATP13A2 ATPase type 13A2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BIRC3 baculoviral IAP repeat containing 3
C11ORF68 chromosome 11 open reading frame 68
C11ORF80 chromosome 11 open reading frame 80
CCRL2 chemokine (C-C motif) receptor-like 2
CCS copper chaperone for superoxide dismutase
CDADC1 cytidine and dCMP deaminase domain containing 1
CEP112 centrosomal protein 112kDa
CLSPN claspin
CNTNAP3B contactin associated protein-like 3B
COMMD10 COMM domain containing 10
CORT cortistatin
CTSK cathepsin K
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHF ets homologous factor
ERF Ets2 repressor factor
ERMP1 endoplasmic reticulum metallopeptidase 1
FADS2 fatty acid desaturase 2
FHOD1 formin homology 2 domain containing 1
FLCN folliculin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRPR gastrin-releasing peptide receptor
GSTT1 glutathione S-transferase theta 1
GUSBP3 glucuronidase, beta pseudogene 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H1T histone cluster 1, H1t
HIST1H2AM histone cluster 1, H2am
HIST2H2BE histone cluster 2, H2be
HYAL3 hyaluronoglucosaminidase 3
IL17RB interleukin 17 receptor B
KIAA1549L KIAA1549-like
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRRK1 leucine-rich repeat kinase 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MCMBP minichromosome maintenance complex binding protein
MCOLN1 mucolipin 1
MED24 mediator complex subunit 24
MTRF1 mitochondrial translational release factor 1
MYL5 myosin, light chain 5, regulatory
MYO9A myosin IXA
NHEJ1 nonhomologous end-joining factor 1
NLK nemo-like kinase
NOL12 nucleolar protein 12
NT5DC3 5'-nucleotidase domain containing 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHACTR4 phosphatase and actin regulator 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR15L proline rich 15-like
PRR3 proline rich 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTCD2 pentatricopeptide repeat domain 2
RAB27B RAB27B, member RAS oncogene family
RUSC2 RUN and SH3 domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35G2 solute carrier family 35, member G2
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPAG4 sperm associated antigen 4
STEAP4 STEAP family member 4
SUOX sulfite oxidase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOR4A torsin family 4, member A
TRAPPC11 trafficking protein particle complex 11
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN12 tetraspanin 12
TTC33 tetratricopeptide repeat domain 33
XAB2 XPA binding protein 2
ZNF165 zinc finger protein 165
ZNF212 zinc finger protein 212
ZNF652 zinc finger protein 652
ZSCAN31 zinc finger and SCAN domain containing 31