kaempferol-6157 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the kaempferol-6157 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADRB3 adrenoceptor beta 3
AICDA activation-induced cytidine deaminase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AREG amphiregulin
ARMCX4 armadillo repeat containing, X-linked 4
ATP9B ATPase, class II, type 9B
AVIL advillin
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D1 B9 protein domain 1
B9D2 B9 protein domain 2
BCAR3 breast cancer anti-estrogen resistance 3
BMP3 bone morphogenetic protein 3
C21ORF2 chromosome 21 open reading frame 2
C2ORF27A chromosome 2 open reading frame 27A
CCNK cyclin K
CDCP1 CUB domain containing protein 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKL3 cyclin-dependent kinase-like 3
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CEP250 centrosomal protein 250kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CIITA class II, major histocompatibility complex, transactivator
CXCL2 chemokine (C-X-C motif) ligand 2
CXXC4 CXXC finger protein 4
DMXL2 Dmx-like 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP4 dual specificity phosphatase 4
EFNA4 ephrin-A4
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHB2 EPH receptor B2
EPS8L3 EPS8-like 3
FGFR2 fibroblast growth factor receptor 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAB1 GRB2-associated binding protein 1
GAN gigaxonin
GLRA1 glycine receptor, alpha 1
GPC1 glypican 1
GPR137 G protein-coupled receptor 137
GPR3 G protein-coupled receptor 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GUK1 guanylate kinase 1
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IL11 interleukin 11
IL16 interleukin 16
ING4 inhibitor of growth family, member 4
IQCG IQ motif containing G
IRF4 interferon regulatory factor 4
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
KYNU kynureninase
LAMB2 laminin, beta 2 (laminin S)
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LMF1 lipase maturation factor 1
LRP1 low density lipoprotein receptor-related protein 1
LRP12 low density lipoprotein receptor-related protein 12
MED25 mediator complex subunit 25
MXD4 MAX dimerization protein 4
MXRA8 matrix-remodelling associated 8
MYL10 myosin, light chain 10, regulatory
NF2 neurofibromin 2 (merlin)
NMT2 N-myristoyltransferase 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
NXPH4 neurexophilin 4
PPAP2B phosphatidic acid phosphatase type 2B
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RNF25 ring finger protein 25
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAA4 serum amyloid A4, constitutive
SCIN scinderin
SEC24D SEC24 family member D
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SFTPB surfactant protein B
SH3YL1 SH3 and SYLF domain containing 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRR serine racemase
ST20 suppressor of tumorigenicity 20
ST7L suppression of tumorigenicity 7 like
SULF1 sulfatase 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TK2 thymidine kinase 2, mitochondrial
TLN2 talin 2
TMEM2 transmembrane protein 2
TPST1 tyrosylprotein sulfotransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP64 ZFP64 zinc finger protein
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADORA3 adenosine A3 receptor
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARRB1 arrestin, beta 1
BBC3 BCL2 binding component 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSPRY B-box and SPRY domain containing
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
CAMKMT calmodulin-lysine N-methyltransferase
CCDC106 coiled-coil domain containing 106
CD101 CD101 molecule
CD1C CD1c molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CDK6 cyclin-dependent kinase 6
CHML choroideremia-like (Rab escort protein 2)
CHMP6 charged multivesicular body protein 6
CISH cytokine inducible SH2-containing protein
CNR2 cannabinoid receptor 2 (macrophage)
CRABP2 cellular retinoic acid binding protein 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DOK3 docking protein 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FAM86C1 family with sequence similarity 86, member C1
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLT3 fms-related tyrosine kinase 3
FUCA1 fucosidase, alpha-L- 1, tissue
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GEMIN8 gem (nuclear organelle) associated protein 8
GLCE glucuronic acid epimerase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR183 G protein-coupled receptor 183
GPX2 glutathione peroxidase 2
GSPT2 G1 to S phase transition 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1T histone cluster 1, H1t
HSPA4L heat shock 70kDa protein 4-like
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
IRF8 interferon regulatory factor 8
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCTD7 potassium channel tetramerization domain containing 7
KIF17 kinesin family member 17
KLF13 Kruppel-like factor 13
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL3 muscleblind-like splicing regulator 3
MTMR12 myotubularin related protein 12
MVP major vault protein
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NBEAL2 neurobeachin-like 2
NCF1C neutrophil cytosolic factor 1C pseudogene
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2 nuclear factor, erythroid 2
NLK nemo-like kinase
NPFFR1 neuropeptide FF receptor 1
NT5DC3 5'-nucleotidase domain containing 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE12 phosphodiesterase 12
PIAS3 protein inhibitor of activated STAT, 3
PID1 phosphotyrosine interaction domain containing 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RIN2 Ras and Rab interactor 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGCE sarcoglycan, epsilon
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SURF2 surfeit 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS4 thrombospondin 4
TRIM58 tripartite motif containing 58
VILL villin-like
XYLT1 xylosyltransferase I
ZBTB38 zinc finger and BTB domain containing 38
ZHX2 zinc fingers and homeoboxes 2
ZNF428 zinc finger protein 428