kaempferol-7196 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the kaempferol-7196 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAGAB alpha- and gamma-adaptin binding protein
AK2 adenylate kinase 2
AKAP4 A kinase (PRKA) anchor protein 4
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ASB1 ankyrin repeat and SOCS box containing 1
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C21ORF2 chromosome 21 open reading frame 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CENPO centromere protein O
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CHST10 carbohydrate sulfotransferase 10
CIDEB cell death-inducing DFFA-like effector b
COL4A1 collagen, type IV, alpha 1
COPA coatomer protein complex, subunit alpha
COPS8 COP9 signalosome subunit 8
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CUL7 cullin 7
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DCAKD dephospho-CoA kinase domain containing
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
ECE1 endothelin converting enzyme 1
EGR3 early growth response 3
ESR1 estrogen receptor 1
FAS Fas cell surface death receptor
FILIP1L filamin A interacting protein 1-like
FLJ21369 uncharacterized protein FLJ21369
FRMD4B FERM domain containing 4B
GJA4 gap junction protein, alpha 4, 37kDa
GPC1 glypican 1
GPR68 G protein-coupled receptor 68
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HLA-G major histocompatibility complex, class I, G
HNMT histamine N-methyltransferase
HOXC8 homeobox C8
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFT22 intraflagellar transport 22
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS4 insulin receptor substrate 4
KIAA0368 KIAA0368
LMAN1 lectin, mannose-binding, 1
LOC257152 uncharacterized LOC257152
LZTR1 leucine-zipper-like transcription regulator 1
MERTK MER proto-oncogene, tyrosine kinase
MFSD11 major facilitator superfamily domain containing 11
NCOA2 nuclear receptor coactivator 2
NF2 neurofibromin 2 (merlin)
NFIB nuclear factor I/B
NPFFR1 neuropeptide FF receptor 1
ORAI2 ORAI calcium release-activated calcium modulator 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDLIM7 PDZ and LIM domain 7 (enigma)
PLK4 polo-like kinase 4
PRB1 proline-rich protein BstNI subfamily 1
PRDM9 PR domain containing 9
PRKCH protein kinase C, eta
PSG9 pregnancy specific beta-1-glycoprotein 9
PTBP3 polypyrimidine tract binding protein 3
RAD51 RAD51 recombinase
RASL11B RAS-like, family 11, member B
RBM3 RNA binding motif (RNP1, RRM) protein 3
RPL7 ribosomal protein L7
S100A13 S100 calcium binding protein A13
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIRT3 sirtuin 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMG7-AS1 SMG7 antisense RNA 1
SNX13 sorting nexin 13
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRED2 sprouty-related, EVH1 domain containing 2
SRI sorcin
SVIL supervillin
TIMP3 TIMP metallopeptidase inhibitor 3
TLE4 transducin-like enhancer of split 4
TMEM120B transmembrane protein 120B
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TTC33 tetratricopeptide repeat domain 33
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZMAT5 zinc finger, matrin-type 5
ZNF235 zinc finger protein 235
ZNF440 zinc finger protein 440
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR2B activin A receptor, type IIB
ADRA2C adrenoceptor alpha 2C
AGO3 argonaute RISC catalytic component 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMDHD2 amidohydrolase domain containing 2
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD3A ATPase family, AAA domain containing 3A
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF95 chromosome 11 open reading frame 95
C19ORF40 chromosome 19 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CBR4 carbonyl reductase 4
CCS copper chaperone for superoxide dismutase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPC centromere protein C
COL9A2 collagen, type IX, alpha 2
COMMD9 COMM domain containing 9
CRIPT cysteine-rich PDZ-binding protein
CTSK cathepsin K
DEAF1 DEAF1 transcription factor
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
EFCAB2 EF-hand calcium binding domain 2
EVPL envoplakin
FCHO1 FCH domain only 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD2 frizzled class receptor 2
GAA glucosidase, alpha; acid
GALT galactose-1-phosphate uridylyltransferase
GNL1 guanine nucleotide binding protein-like 1
GUSBP3 glucuronidase, beta pseudogene 3
H1FX H1 histone family, member X
HIST1H2AI histone cluster 1, H2ai
INSIG2 insulin induced gene 2
LAMA3 laminin, alpha 3
LOC100272216 uncharacterized LOC100272216
LRP3 low density lipoprotein receptor-related protein 3
LRRC8E leucine rich repeat containing 8 family, member E
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEF1 melanoma antigen family F1
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP7D1 MAP7 domain containing 1
MBD5 methyl-CpG binding domain protein 5
MBIP MAP3K12 binding inhibitory protein 1
MEIS1 Meis homeobox 1
MFSD12 major facilitator superfamily domain containing 12
MUM1 melanoma associated antigen (mutated) 1
NABP2 nucleic acid binding protein 2
NES nestin
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUPL2 nucleoporin like 2
PAQR3 progestin and adipoQ receptor family member III
PCDHB3 protocadherin beta 3
PCNXL4 pecanex-like 4 (Drosophila)
PGPEP1 pyroglutamyl-peptidase I
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRR15L proline rich 15-like
RAB33B RAB33B, member RAS oncogene family
RGS17 regulator of G-protein signaling 17
RIPPLY3 ripply transcriptional repressor 3
RLN2 relaxin 2
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RWDD2A RWD domain containing 2A
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SIL1 SIL1 nucleotide exchange factor
SIRT1 sirtuin 1
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMA4 glucuronidase, beta pseudogene
SP140L SP140 nuclear body protein-like
SSBP2 single-stranded DNA binding protein 2
STAG3 stromal antigen 3
TBX19 T-box 19
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBS3 thrombospondin 3
TMEM132A transmembrane protein 132A
TNS2 tensin 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPST1 tyrosylprotein sulfotransferase 1
TPST2 tyrosylprotein sulfotransferase 2
TRAF5 TNF receptor-associated factor 5
TRAPPC2 trafficking protein particle complex 2
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC30A tetratricopeptide repeat domain 30A
UNKL unkempt family zinc finger-like
USP18 ubiquitin specific peptidase 18
VAV1 vav 1 guanine nucleotide exchange factor
WDR47 WD repeat domain 47
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF219 zinc finger protein 219
ZNF248 zinc finger protein 248
ZNF273 zinc finger protein 273