kanamycin-3224 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the kanamycin-3224 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ADCK2 aarF domain containing kinase 2
ALDOB aldolase B, fructose-bisphosphate
ALS2CL ALS2 C-terminal like
ARHGAP26 Rho GTPase activating protein 26
ASIC2 acid sensing (proton gated) ion channel 2
BGLAP bone gamma-carboxyglutamate (gla) protein
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CD300C CD300c molecule
CD58 CD58 molecule
CLSTN3 calsyntenin 3
CNTNAP2 contactin associated protein-like 2
COL6A1 collagen, type VI, alpha 1
CPA4 carboxypeptidase A4
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DICER1 dicer 1, ribonuclease type III
EDN3 endothelin 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FAIM2 Fas apoptotic inhibitory molecule 2
FCMR Fc fragment of IgM receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FGF2 fibroblast growth factor 2 (basic)
FLT3LG fms-related tyrosine kinase 3 ligand
FRMD4A FERM domain containing 4A
GLIPR1 GLI pathogenesis-related 1
GSTA1 glutathione S-transferase alpha 1
HDAC5 histone deacetylase 5
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H2BO histone cluster 1, H2bo
HP haptoglobin
HSPG2 heparan sulfate proteoglycan 2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL23A interleukin 23, alpha subunit p19
KIF25 kinesin family member 25
KRT83 keratin 83, type II
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP2 latent transforming growth factor beta binding protein 2
MEG3 maternally expressed 3 (non-protein coding)
METTL7A methyltransferase like 7A
MTMR3 myotubularin related protein 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOD1 nucleotide-binding oligomerization domain containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIPOX pipecolic acid oxidase
PITX1 paired-like homeodomain 1
PLAU plasminogen activator, urokinase
PRB1 proline-rich protein BstNI subfamily 1
PRDX2 peroxiredoxin 2
PTCRA pre T-cell antigen receptor alpha
PTHLH parathyroid hormone-like hormone
PTPRM protein tyrosine phosphatase, receptor type, M
PVT1 Pvt1 oncogene (non-protein coding)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RND2 Rho family GTPase 2
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL10 ribosomal protein L10
RPL23AP53 ribosomal protein L23a pseudogene 53
RSU1 Ras suppressor protein 1
SARDH sarcosine dehydrogenase
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCRN3 secernin 3
SIRPA signal-regulatory protein alpha
SIRT6 sirtuin 6
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS1 sorbin and SH3 domain containing 1
SPTB spectrin, beta, erythrocytic
SSX3 synovial sarcoma, X breakpoint 3
STXBP5L syntaxin binding protein 5-like
SYT5 synaptotagmin V
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFEB transcription factor EB
TFR2 transferrin receptor 2
TMEM53 transmembrane protein 53
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOR4A torsin family 4, member A
TRPC1 transient receptor potential cation channel, subfamily C, member 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTRN utrophin
WLS wntless Wnt ligand secretion mediator
WNT5A wingless-type MMTV integration site family, member 5A
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF280A zinc finger protein 280A
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARRB1 arrestin, beta 1
BAHCC1 BAH domain and coiled-coil containing 1
BCOR BCL6 corepressor
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C11ORF63 chromosome 11 open reading frame 63
C2ORF44 chromosome 2 open reading frame 44
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC132 coiled-coil domain containing 132
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CEMIP cell migration inducing protein, hyaluronan binding
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCN2 chloride channel, voltage-sensitive 2
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
CRABP1 cellular retinoic acid binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CRLF1 cytokine receptor-like factor 1
CRYGC crystallin, gamma C
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CXORF56 chromosome X open reading frame 56
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF5A2 eukaryotic translation initiation factor 5A2
EXD3 exonuclease 3'-5' domain containing 3
FAM169A family with sequence similarity 169, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL2 F-box and leucine-rich repeat protein 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUZ fuzzy planar cell polarity protein
GATA4 GATA binding protein 4
GLCE glucuronic acid epimerase
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H2AK histone cluster 1, H2ak
HIST1H2BJ histone cluster 1, H2bj
HIST1H4F histone cluster 1, H4f
HOXC5 homeobox C5
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL12 kelch-like family member 12
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYZ lysozyme
LZTS3 leucine zipper, putative tumor suppressor family member 3
MRPS18C mitochondrial ribosomal protein S18C
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
NBEAL2 neurobeachin-like 2
NLGN1 neuroligin 1
OTUD3 OTU deubiquitinase 3
PCBP4 poly(rC) binding protein 4
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PGPEP1 pyroglutamyl-peptidase I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PSKH1 protein serine kinase H1
PYCRL pyrroline-5-carboxylate reductase-like
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS20 regulator of G-protein signaling 20
ROM1 retinal outer segment membrane protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SRD5A3 steroid 5 alpha-reductase 3
TCTA T-cell leukemia translocation altered
TDRD1 tudor domain containing 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TNS2 tensin 2
TRIM5 tripartite motif containing 5
TSPAN15 tetraspanin 15
TSPAN5 tetraspanin 5
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFC vascular endothelial growth factor C
WDR91 WD repeat domain 91
ZBTB22 zinc finger and BTB domain containing 22
ZNF428 zinc finger protein 428
ZNF510 zinc finger protein 510
ZNF552 zinc finger protein 552
ZNF8 zinc finger protein 8