kanamycin Gene Set
Genes
30 genes differentially expressed following the kanamycin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EPHB2
|
EPH receptor B2
|
5.1931
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.71674
|
|
SIK1
|
salt-inducible kinase 1
|
3.8323
|
|
MAP7
|
microtubule-associated protein 7
|
3.54113
|
|
TLX1
|
T-cell leukemia homeobox 1
|
3.47189
|
|
TICAM1
|
toll-like receptor adaptor molecule 1
|
3.43795
|
|
TNFSF9
|
tumor necrosis factor (ligand) superfamily, member 9
|
3.41735
|
|
TMEM164
|
transmembrane protein 164
|
3.24508
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
3.12103
|
|
RASA1
|
RAS p21 protein activator (GTPase activating protein) 1
|
3.10993
|
|
MISP
|
mitotic spindle positioning
|
3.0952
|
|
VRTN
|
vertebrae development associated
|
3.09277
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.031
|
|
ZPBP
|
zona pellucida binding protein
|
3.02593
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GLI2
|
GLI family zinc finger 2
|
-4.26072
|
|
SLC2A11
|
solute carrier family 2 (facilitated glucose transporter), member 11
|
-3.94232
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-3.80872
|
|
NCK1
|
NCK adaptor protein 1
|
-3.69277
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-3.66777
|
|
CD81
|
CD81 molecule
|
-3.54965
|
|
PACRG
|
PARK2 co-regulated
|
-3.50716
|
|
LTB
|
lymphotoxin beta (TNF superfamily, member 3)
|
-3.4633
|
|
KMO
|
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
|
-3.38246
|
|
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
|
-3.26329
|
|
CCR6
|
chemokine (C-C motif) receptor 6
|
-3.22094
|
|
BHMT2
|
betaine--homocysteine S-methyltransferase 2
|
-3.18294
|
|
MRAP
|
melanocortin 2 receptor accessory protein
|
-3.17993
|
|
ATP6V0E2
|
ATPase, H+ transporting V0 subunit e2
|
-3.06182
|
|
HNMT
|
histamine N-methyltransferase
|
-3.03527
|
|
ALOX15
|
arachidonate 15-lipoxygenase
|
-3.03245
|
