| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the karakoline-2203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BAIAP2 | BAI1-associated protein 2 |
| BMP15 | bone morphogenetic protein 15 |
| BMP7 | bone morphogenetic protein 7 |
| BTNL3 | butyrophilin-like 3 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C4BPA | complement component 4 binding protein, alpha |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CHPF | chondroitin polymerizing factor |
| CLDN7 | claudin 7 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNTN1 | contactin 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPNE7 | copine VII |
| CRAT | carnitine O-acetyltransferase |
| CREBZF | CREB/ATF bZIP transcription factor |
| CYP2A7P1 | cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAPK3 | death-associated protein kinase 3 |
| DDO | D-aspartate oxidase |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DOK5 | docking protein 5 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EPN2 | epsin 2 |
| EPS8L1 | EPS8-like 1 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FCAR | Fc fragment of IgA receptor |
| FLT1 | fms-related tyrosine kinase 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTPBP1 | GTP binding protein 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HDAC7 | histone deacetylase 7 |
| HFE | hemochromatosis |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HOXA11 | homeobox A11 |
| HOXC11 | homeobox C11 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KRT2 | keratin 2, type II |
| LAG3 | lymphocyte-activation gene 3 |
| LMF2 | lipase maturation factor 2 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MLXIPL | MLX interacting protein-like |
| MMP25 | matrix metallopeptidase 25 |
| MTMR3 | myotubularin related protein 3 |
| MX1 | MX dynamin-like GTPase 1 |
| NDRG2 | NDRG family member 2 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NOP16 | NOP16 nucleolar protein |
| NPR2 | natriuretic peptide receptor 2 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRF1 | nuclear respiratory factor 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NUP188 | nucleoporin 188kDa |
| OLFML2B | olfactomedin-like 2B |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLD3 | phospholipase D family, member 3 |
| PMEL | premelanosome protein |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PRY | PTPN13-like, Y-linked |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RB1 | retinoblastoma 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHO | rhodopsin |
| RNF39 | ring finger protein 39 |
| RPGRIP1L | RPGRIP1-like |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLAMF7 | SLAM family member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TFF2 | trefoil factor 2 |
| THAP10 | THAP domain containing 10 |
| TNIK | TRAF2 and NCK interacting kinase |
| TPM1 | tropomyosin 1 (alpha) |
| TRD | T cell receptor delta locus |
| TRIM10 | tripartite motif containing 10 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSPAN2 | tetraspanin 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOL6 | apolipoprotein L, 6 |
| ARSB | arylsulfatase B |
| ASPN | asporin |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CASZ1 | castor zinc finger 1 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CEP97 | centrosomal protein 97kDa |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNN2 | calponin 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORO7 | coronin 7 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DBR1 | debranching RNA lariats 1 |
| DDN | dendrin |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FOXC1 | forkhead box C1 |
| FRMD1 | FERM domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GALK1 | galactokinase 1 |
| HIST1H1T | histone cluster 1, H1t |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IFT140 | intraflagellar transport 140 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLK6 | kallikrein-related peptidase 6 |
| KPTN | kaptin (actin binding protein) |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MCPH1 | microcephalin 1 |
| METTL8 | methyltransferase like 8 |
| MON1B | MON1 secretory trafficking family member B |
| MUC3A | mucin 3A, cell surface associated |
| NARFL | nuclear prelamin A recognition factor-like |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDE1 | nudE neurodevelopment protein 1 |
| NINJ1 | ninjurin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PNOC | prepronociceptin |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PRO2964 | uncharacterized protein PRO2964 |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RCAN3 | RCAN family member 3 |
| RHBDD3 | rhomboid domain containing 3 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RNF122 | ring finger protein 122 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNHG20 | small nucleolar RNA host gene 20 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STRA6 | stimulated by retinoic acid 6 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAGLN | transgelin |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TIGD6 | tigger transposable element derived 6 |
| TMEM120B | transmembrane protein 120B |
| TMEM2 | transmembrane protein 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA4B | tubulin, alpha 4b |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| URM1 | ubiquitin related modifier 1 |
| USP36 | ubiquitin specific peptidase 36 |
| WDR62 | WD repeat domain 62 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF528 | zinc finger protein 528 |