karakoline-2203 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the karakoline-2203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ANXA2P3 annexin A2 pseudogene 3
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BAIAP2 BAI1-associated protein 2
BMP15 bone morphogenetic protein 15
BMP7 bone morphogenetic protein 7
BTNL3 butyrophilin-like 3
C20ORF27 chromosome 20 open reading frame 27
C4BPA complement component 4 binding protein, alpha
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CEND1 cell cycle exit and neuronal differentiation 1
CHPF chondroitin polymerizing factor
CLDN7 claudin 7
CLIP2 CAP-GLY domain containing linker protein 2
CNTN1 contactin 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CRAT carnitine O-acetyltransferase
CREBZF CREB/ATF bZIP transcription factor
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPK3 death-associated protein kinase 3
DDO D-aspartate oxidase
DDR1 discoidin domain receptor tyrosine kinase 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOK5 docking protein 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPN2 epsin 2
EPS8L1 EPS8-like 1
FASLG Fas ligand (TNF superfamily, member 6)
FCAR Fc fragment of IgA receptor
FLT1 fms-related tyrosine kinase 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTPBP1 GTP binding protein 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HDAC7 histone deacetylase 7
HFE hemochromatosis
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HOXA11 homeobox A11
HOXC11 homeobox C11
IQSEC1 IQ motif and Sec7 domain 1
KRT2 keratin 2, type II
LAG3 lymphocyte-activation gene 3
LMF2 lipase maturation factor 2
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MLXIPL MLX interacting protein-like
MMP25 matrix metallopeptidase 25
MTMR3 myotubularin related protein 3
MX1 MX dynamin-like GTPase 1
NDRG2 NDRG family member 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NLRP1 NLR family, pyrin domain containing 1
NOP16 NOP16 nucleolar protein
NPR2 natriuretic peptide receptor 2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRF1 nuclear respiratory factor 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP188 nucleoporin 188kDa
OLFML2B olfactomedin-like 2B
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCLO piccolo presynaptic cytomatrix protein
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PKNOX1 PBX/knotted 1 homeobox 1
PLD3 phospholipase D family, member 3
PMEL premelanosome protein
PPAP2B phosphatidic acid phosphatase type 2B
PRY PTPN13-like, Y-linked
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RB1 retinoblastoma 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHO rhodopsin
RNF39 ring finger protein 39
RPGRIP1L RPGRIP1-like
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RTEL1 regulator of telomere elongation helicase 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLAMF7 SLAM family member 7
SLMO1 slowmo homolog 1 (Drosophila)
SORBS3 sorbin and SH3 domain containing 3
SYNE1 spectrin repeat containing, nuclear envelope 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFF2 trefoil factor 2
THAP10 THAP domain containing 10
TNIK TRAF2 and NCK interacting kinase
TPM1 tropomyosin 1 (alpha)
TRD T cell receptor delta locus
TRIM10 tripartite motif containing 10
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSPAN2 tetraspanin 2
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOL6 apolipoprotein L, 6
ARSB arylsulfatase B
ASPN asporin
C14ORF93 chromosome 14 open reading frame 93
CASZ1 castor zinc finger 1
CBY1 chibby homolog 1 (Drosophila)
CEP97 centrosomal protein 97kDa
CLCN2 chloride channel, voltage-sensitive 2
CNN2 calponin 2
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBR1 debranching RNA lariats 1
DDN dendrin
DGAT1 diacylglycerol O-acyltransferase 1
DNAL4 dynein, axonemal, light chain 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF5A2 eukaryotic translation initiation factor 5A2
EMILIN2 elastin microfibril interfacer 2
EPX eosinophil peroxidase
ERCC2 excision repair cross-complementation group 2
ERCC6L excision repair cross-complementation group 6-like
ERN2 endoplasmic reticulum to nucleus signaling 2
FOXC1 forkhead box C1
FRMD1 FERM domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GALK1 galactokinase 1
HIST1H1T histone cluster 1, H1t
HLA-DMB major histocompatibility complex, class II, DM beta
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KLK6 kallikrein-related peptidase 6
KPTN kaptin (actin binding protein)
LAMP5 lysosomal-associated membrane protein family, member 5
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRK1 leucine-rich repeat kinase 1
LTBP2 latent transforming growth factor beta binding protein 2
MCPH1 microcephalin 1
METTL8 methyltransferase like 8
MON1B MON1 secretory trafficking family member B
MUC3A mucin 3A, cell surface associated
NARFL nuclear prelamin A recognition factor-like
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDE1 nudE neurodevelopment protein 1
NINJ1 ninjurin 1
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PCDHGA10 protocadherin gamma subfamily A, 10
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PNOC prepronociceptin
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRO2964 uncharacterized protein PRO2964
PYHIN1 pyrin and HIN domain family, member 1
RCAN3 RCAN family member 3
RHBDD3 rhomboid domain containing 3
RNASE3 ribonuclease, RNase A family, 3
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNHG20 small nucleolar RNA host gene 20
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRA6 stimulated by retinoic acid 6
SULT4A1 sulfotransferase family 4A, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN transgelin
TBXAS1 thromboxane A synthase 1 (platelet)
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
TMEM2 transmembrane protein 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URM1 ubiquitin related modifier 1
USP36 ubiquitin specific peptidase 36
WDR62 WD repeat domain 62
ZBTB25 zinc finger and BTB domain containing 25
ZFHX2 zinc finger homeobox 2
ZFP37 ZFP37 zinc finger protein
ZNF528 zinc finger protein 528