| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the karakoline-3638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| AGRN | agrin |
| AJAP1 | adherens junctions associated protein 1 |
| AK2 | adenylate kinase 2 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BRD9 | bromodomain containing 9 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CD101 | CD101 molecule |
| CD7 | CD7 molecule |
| CD80 | CD80 molecule |
| CD82 | CD82 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| COL5A2 | collagen, type V, alpha 2 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSF1R | colony stimulating factor 1 receptor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DCHS1 | dachsous cadherin-related 1 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| ECE1 | endothelin converting enzyme 1 |
| EDA | ectodysplasin A |
| EFNB3 | ephrin-B3 |
| EN2 | engrailed homeobox 2 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| ESM1 | endothelial cell-specific molecule 1 |
| EXT1 | exostosin glycosyltransferase 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM171A1 | family with sequence similarity 171, member A1 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GAP43 | growth associated protein 43 |
| GDF5 | growth differentiation factor 5 |
| GNRH2 | gonadotropin-releasing hormone 2 |
| HBB | hemoglobin, beta |
| HFE | hemochromatosis |
| HIST1H2BB | histone cluster 1, H2bb |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| ING2 | inhibitor of growth family, member 2 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITGB6 | integrin, beta 6 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIAA0125 | KIAA0125 |
| KIAA0319L | KIAA0319-like |
| KRT19P2 | keratin 19 pseudogene 2 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MEF2D | myocyte enhancer factor 2D |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NELL2 | NEL-like 2 (chicken) |
| NLGN1 | neuroligin 1 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NOTCH4 | notch 4 |
| NYX | nyctalopin |
| PAX2 | paired box 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLTP | phospholipid transfer protein |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRDM12 | PR domain containing 12 |
| RAP2B | RAP2B, member of RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REEP2 | receptor accessory protein 2 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RPLP2 | ribosomal protein, large, P2 |
| S100B | S100 calcium binding protein B |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SPHK2 | sphingosine kinase 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SYN2 | synapsin II |
| TBX3 | T-box 3 |
| TEF | thyrotrophic embryonic factor |
| TFR2 | transferrin receptor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSC2 | tuberous sclerosis 2 |
| VCX2 | variable charge, X-linked 2 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF304 | zinc finger protein 304 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AIRE | autoimmune regulator |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOL6 | apolipoprotein L, 6 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C3 | complement component 3 |
| CD1A | CD1a molecule |
| CD8A | CD8a molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK18 | cyclin-dependent kinase 18 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CDO1 | cysteine dioxygenase type 1 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CNPY4 | canopy FGF signaling regulator 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSTA | cystatin A (stefin A) |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXXC4 | CXXC finger protein 4 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DLL3 | delta-like 3 (Drosophila) |
| DOK2 | docking protein 2, 56kDa |
| DOK5 | docking protein 5 |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FFAR2 | free fatty acid receptor 2 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GPX2 | glutathione peroxidase 2 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3F | histone cluster 1, H3f |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL2RB | interleukin 2 receptor, beta |
| INHBE | inhibin, beta E |
| ITM2C | integral membrane protein 2C |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LEFTY1 | left-right determination factor 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LSP1 | lymphocyte-specific protein 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MICALL2 | MICAL-like 2 |
| MMP13 | matrix metallopeptidase 13 |
| MX1 | MX dynamin-like GTPase 1 |
| MYOZ3 | myozenin 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPR3 | natriuretic peptide receptor 3 |
| NPTX1 | neuronal pentraxin I |
| NPY4R | neuropeptide Y receptor Y4 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NRN1 | neuritin 1 |
| OLAH | oleoyl-ACP hydrolase |
| ONECUT1 | one cut homeobox 1 |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PMCH | pro-melanin-concentrating hormone |
| POLM | polymerase (DNA directed), mu |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB3A | RAB3A, member RAS oncogene family |
| RNF123 | ring finger protein 123 |
| RPGRIP1L | RPGRIP1-like |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNCAIP | synuclein, alpha interacting protein |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR2B | small proline-rich protein 2B |
| STEAP4 | STEAP family member 4 |
| TAOK1 | TAO kinase 1 |
| TEX40 | testis expressed 40 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TUBA3C | tubulin, alpha 3c |
| VN1R1 | vomeronasal 1 receptor 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF76 | zinc finger protein 76 |