karakoline-3638 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the karakoline-3638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
AGRN agrin
AJAP1 adherens junctions associated protein 1
AK2 adenylate kinase 2
ARHGAP1 Rho GTPase activating protein 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BRD9 bromodomain containing 9
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C14ORF79 chromosome 14 open reading frame 79
CD101 CD101 molecule
CD7 CD7 molecule
CD80 CD80 molecule
CD82 CD82 molecule
CDON cell adhesion associated, oncogene regulated
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL5A2 collagen, type V, alpha 2
COL8A2 collagen, type VIII, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSF1R colony stimulating factor 1 receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCHS1 dachsous cadherin-related 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNAI2 dynein, axonemal, intermediate chain 2
DPY19L1P1 DPY19L1 pseudogene 1
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EFNB3 ephrin-B3
EN2 engrailed homeobox 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESM1 endothelial cell-specific molecule 1
EXT1 exostosin glycosyltransferase 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM171A1 family with sequence similarity 171, member A1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAP43 growth associated protein 43
GDF5 growth differentiation factor 5
GNRH2 gonadotropin-releasing hormone 2
HBB hemoglobin, beta
HFE hemochromatosis
HIST1H2BB histone cluster 1, H2bb
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
ING2 inhibitor of growth family, member 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB6 integrin, beta 6
KANK1 KN motif and ankyrin repeat domains 1
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KRT19P2 keratin 19 pseudogene 2
LINC00652 long intergenic non-protein coding RNA 652
MEF2D myocyte enhancer factor 2D
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MKL1 megakaryoblastic leukemia (translocation) 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NELL2 NEL-like 2 (chicken)
NLGN1 neuroligin 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH4 notch 4
NYX nyctalopin
PAX2 paired box 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLTP phospholipid transfer protein
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM12 PR domain containing 12
RAP2B RAP2B, member of RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REEP2 receptor accessory protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RPLP2 ribosomal protein, large, P2
S100B S100 calcium binding protein B
SEC14L4 SEC14-like 4 (S. cerevisiae)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPHK2 sphingosine kinase 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUN1 Sad1 and UNC84 domain containing 1
SYN2 synapsin II
TBX3 T-box 3
TEF thyrotrophic embryonic factor
TFR2 transferrin receptor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSC2 tuberous sclerosis 2
VCX2 variable charge, X-linked 2
ZFAND5 zinc finger, AN1-type domain 5
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF304 zinc finger protein 304
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AIRE autoimmune regulator
AKAP5 A kinase (PRKA) anchor protein 5
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL6 apolipoprotein L, 6
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C1ORF21 chromosome 1 open reading frame 21
C3 complement component 3
CD1A CD1a molecule
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CDO1 cysteine dioxygenase type 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNPY4 canopy FGF signaling regulator 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSTA cystatin A (stefin A)
CUZD1 CUB and zona pellucida-like domains 1
CXXC4 CXXC finger protein 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKE diacylglycerol kinase, epsilon 64kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DLL3 delta-like 3 (Drosophila)
DOK2 docking protein 2, 56kDa
DOK5 docking protein 5
EPN1 epsin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
F2RL2 coagulation factor II (thrombin) receptor-like 2
FFAR2 free fatty acid receptor 2
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H2BM histone cluster 1, H2bm
HIST1H3F histone cluster 1, H3f
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL2RB interleukin 2 receptor, beta
INHBE inhibin, beta E
ITM2C integral membrane protein 2C
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LEFTY1 left-right determination factor 1
LIME1 Lck interacting transmembrane adaptor 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LSP1 lymphocyte-specific protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MICALL2 MICAL-like 2
MMP13 matrix metallopeptidase 13
MX1 MX dynamin-like GTPase 1
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPR3 natriuretic peptide receptor 3
NPTX1 neuronal pentraxin I
NPY4R neuropeptide Y receptor Y4
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRN1 neuritin 1
OLAH oleoyl-ACP hydrolase
ONECUT1 one cut homeobox 1
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PMCH pro-melanin-concentrating hormone
POLM polymerase (DNA directed), mu
PPARG peroxisome proliferator-activated receptor gamma
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3A RAB3A, member RAS oncogene family
RNF123 ring finger protein 123
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SHANK1 SH3 and multiple ankyrin repeat domains 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC35G2 solute carrier family 35, member G2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SNCAIP synuclein, alpha interacting protein
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR2B small proline-rich protein 2B
STEAP4 STEAP family member 4
TAOK1 TAO kinase 1
TEX40 testis expressed 40
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TM4SF5 transmembrane 4 L six family member 5
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TUBA3C tubulin, alpha 3c
VN1R1 vomeronasal 1 receptor 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF76 zinc finger protein 76