| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the karakoline-3741 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY2 | adenylate cyclase 2 (brain) |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| ANXA10 | annexin A10 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC9 | armadillo repeat containing 9 |
| ARSE | arylsulfatase E (chondrodysplasia punctata 1) |
| ATF5 | activating transcription factor 5 |
| ATF6B | activating transcription factor 6 beta |
| ATG10 | autophagy related 10 |
| ATP10B | ATPase, class V, type 10B |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CARF | calcium responsive transcription factor |
| CCDC134 | coiled-coil domain containing 134 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| CLDN8 | claudin 8 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| DKFZP434C153 | DKFZP434C153 protein |
| DUSP2 | dual specificity phosphatase 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGR1 | early growth response 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGF22 | fibroblast growth factor 22 |
| FHL3 | four and a half LIM domains 3 |
| GLYAT | glycine-N-acyltransferase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H3F | histone cluster 1, H3f |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL1RN | interleukin 1 receptor antagonist |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLK10 | kallikrein-related peptidase 10 |
| KRT17 | keratin 17, type I |
| MAPK11 | mitogen-activated protein kinase 11 |
| MEGF8 | multiple EGF-like-domains 8 |
| MMP10 | matrix metallopeptidase 10 |
| MPZ | myelin protein zero |
| MRC2 | mannose receptor, C type 2 |
| MST1 | macrophage stimulating 1 |
| NAV3 | neuron navigator 3 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NTF3 | neurotrophin 3 |
| NUP214 | nucleoporin 214kDa |
| PAX8 | paired box 8 |
| PDE12 | phosphodiesterase 12 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLK4 | polo-like kinase 4 |
| PLXND1 | plexin D1 |
| POU2F2 | POU class 2 homeobox 2 |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAD51 | RAD51 recombinase |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASL11B | RAS-like, family 11, member B |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RECQL5 | RecQ protein-like 5 |
| RNF17 | ring finger protein 17 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SKIL | SKI-like proto-oncogene |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STAB2 | stabilin 2 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBX6 | T-box 6 |
| TJP3 | tight junction protein 3 |
| TNS1 | tensin 1 |
| TNXB | tenascin XB |
| TSPAN9 | tetraspanin 9 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF345 | zinc finger protein 345 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AK5 | adenylate kinase 5 |
| AMN | amnion associated transmembrane protein |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BDKRB1 | bradykinin receptor B1 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCDC7 | coiled-coil domain containing 7 |
| CDH19 | cadherin 19, type 2 |
| CEP41 | centrosomal protein 41kDa |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CLDN1 | claudin 1 |
| CORT | cortistatin |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM120C | family with sequence similarity 120C |
| FAM46C | family with sequence similarity 46, member C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GMPR | guanosine monophosphate reductase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4F | histone cluster 1, H4f |
| HOMER2 | homer scaffolding protein 2 |
| HOXA4 | homeobox A4 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFNA17 | interferon, alpha 17 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCC | IQ motif containing C |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| LMTK2 | lemur tyrosine kinase 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRAS | muscle RAS oncogene homolog |
| MYOZ3 | myozenin 3 |
| NARFL | nuclear prelamin A recognition factor-like |
| NELL2 | NEL-like 2 (chicken) |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PC | pyruvate carboxylase |
| PER3 | period circadian clock 3 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PODNL1 | podocan-like 1 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RLN1 | relaxin 1 |
| RPL10L | ribosomal protein L10-like |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCP10 | t-complex 10 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX15 | testis expressed 15 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM74B | transmembrane protein 74B |
| TRAC | T cell receptor alpha constant |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VGF | VGF nerve growth factor inducible |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZNF528 | zinc finger protein 528 |
| ZNF573 | zinc finger protein 573 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
