| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the karakoline-6059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AMACR | alpha-methylacyl-CoA racemase |
| ANGPT4 | angiopoietin 4 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ATF6B | activating transcription factor 6 beta |
| ATP10B | ATPase, class V, type 10B |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCO1 | beta-carotene oxygenase 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CA6 | carbonic anhydrase VI |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CARF | calcium responsive transcription factor |
| CCDC28B | coiled-coil domain containing 28B |
| CDX1 | caudal type homeobox 1 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTSZ | cathepsin Z |
| CUL7 | cullin 7 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPP4 | dipeptidyl-peptidase 4 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| ECE1 | endothelin converting enzyme 1 |
| EDA | ectodysplasin A |
| EGFL7 | EGF-like-domain, multiple 7 |
| EMP1 | epithelial membrane protein 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| EXPH5 | exophilin 5 |
| FAM212B | family with sequence similarity 212, member B |
| FGF9 | fibroblast growth factor 9 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FN1 | fibronectin 1 |
| FOXE1 | forkhead box E1 |
| GCGR | glucagon receptor |
| GFER | growth factor, augmenter of liver regeneration |
| GPX5 | glutathione peroxidase 5 |
| GSN | gelsolin |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H3F | histone cluster 1, H3f |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KLHL25 | kelch-like family member 25 |
| KRT83 | keratin 83, type II |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MED16 | mediator complex subunit 16 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MVB12B | multivesicular body subunit 12B |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| NAG18 | NAG18 mRNA |
| NTM | neurotrimin |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHF8 | PHD finger protein 8 |
| POU6F1 | POU class 6 homeobox 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRAMEF11 | PRAME family member 11 |
| PRKCB | protein kinase C, beta |
| PSCA | prostate stem cell antigen |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| RAB6B | RAB6B, member RAS oncogene family |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAFB2 | scaffold attachment factor B2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SDC2 | syndecan 2 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| STK24 | serine/threonine kinase 24 |
| SYNPO2L | synaptopodin 2-like |
| SYT12 | synaptotagmin XII |
| TAAR5 | trace amine associated receptor 5 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TRD | T cell receptor delta locus |
| TSC22D2 | TSC22 domain family, member 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VCX2 | variable charge, X-linked 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF3 | zinc finger protein 3 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANKRD40 | ankyrin repeat domain 40 |
| ARMC4 | armadillo repeat containing 4 |
| ARRB1 | arrestin, beta 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AUTS2 | autism susceptibility candidate 2 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BMP4 | bone morphogenetic protein 4 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBX8 | chromobox homolog 8 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CDON | cell adhesion associated, oncogene regulated |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COCH | cochlin |
| CPB1 | carboxypeptidase B1 (tissue) |
| CTSF | cathepsin F |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSPP | dentin sialophosphoprotein |
| EFNA3 | ephrin-A3 |
| EXO5 | exonuclease 5 |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H4F | histone cluster 1, H4f |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL22 | interleukin 22 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LMX1B | LIM homeobox transcription factor 1, beta |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCOLN1 | mucolipin 1 |
| MITF | microphthalmia-associated transcription factor |
| MMP3 | matrix metallopeptidase 3 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ONECUT2 | one cut homeobox 2 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PORCN | porcupine homolog (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFX7 | regulatory factor X, 7 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD2A | RWD domain containing 2A |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLN | sarcolipin |
| SPAG4 | sperm associated antigen 4 |
| SPRYD7 | SPRY domain containing 7 |
| SRPX | sushi-repeat containing protein, X-linked |
| TBC1D19 | TBC1 domain family, member 19 |
| TLR5 | toll-like receptor 5 |
| TMEM183A | transmembrane protein 183A |
| TRIM5 | tripartite motif containing 5 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWISTNB | TWIST neighbor |
| UBQLN4 | ubiquilin 4 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WLS | wntless Wnt ligand secretion mediator |
| YY2 | YY2 transcription factor |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF10 | zinc finger protein 10 |
| ZNF136 | zinc finger protein 136 |
| ZNF141 | zinc finger protein 141 |
| ZNF212 | zinc finger protein 212 |
| ZNF532 | zinc finger protein 532 |
| ZNF862 | zinc finger protein 862 |
